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Network neighborhood for query Sequence : ORAI3_HUMAN

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ORAI3_HUMAN
SwissProt Accessions	Q9BRQ5, Q96BI8	Gene names	TMEM142C, ORAI3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ORAI3_MOUSE
θ value	5.59392e-143 (rank : 1)	NC score	0.996732 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

ORAI3_HUMAN
θ value	2.87295e-139 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BRQ5, Q96BI8	Gene names	TMEM142C, ORAI3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

CRCM1_HUMAN
θ value	2.73302e-81 (rank : 3)	NC score	0.986619 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

CRCM1_MOUSE
θ value	1.35638e-80 (rank : 4)	NC score	0.986622 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWG9, Q8BUD4, Q8R586	Gene names	Tmem142a, Cracm1, Orai1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

ORAI2_MOUSE
θ value	4.82422e-78 (rank : 5)	NC score	0.984010 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH10, Q8C953	Gene names	Tmem142b, Orai2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B).

ORAI2_HUMAN
θ value	6.52014e-75 (rank : 6)	NC score	0.983795 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SN7	Gene names	TMEM142B, C7orf19, CBCIP2, ORAI2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B) (CAP-binding protein complex-interacting protein 2).

MK07_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.002983 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1087	Shared Neighborhood Hits	3
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

CX022_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.053052 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

SPHK1_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.027095 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

VWF_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.005766 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

Hits sorted by NC score

ORAI3_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.87295e-139 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BRQ5, Q96BI8	Gene names	TMEM142C, ORAI3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

ORAI3_MOUSE
NC score	0.996732 (rank : 2)	θ value	5.59392e-143 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

CRCM1_MOUSE
NC score	0.986622 (rank : 3)	θ value	1.35638e-80 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWG9, Q8BUD4, Q8R586	Gene names	Tmem142a, Cracm1, Orai1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

CRCM1_HUMAN
NC score	0.986619 (rank : 4)	θ value	2.73302e-81 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

ORAI2_MOUSE
NC score	0.984010 (rank : 5)	θ value	4.82422e-78 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH10, Q8C953	Gene names	Tmem142b, Orai2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B).

ORAI2_HUMAN
NC score	0.983795 (rank : 6)	θ value	6.52014e-75 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SN7	Gene names	TMEM142B, C7orf19, CBCIP2, ORAI2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B) (CAP-binding protein complex-interacting protein 2).

CX022_HUMAN
NC score	0.053052 (rank : 7)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

SPHK1_HUMAN
NC score	0.027095 (rank : 8)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

VWF_HUMAN
NC score	0.005766 (rank : 9)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MK07_HUMAN
NC score	0.002983 (rank : 10)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1087	Shared Neighborhood Hits	3
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).