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Network neighborhood for query Sequence : CRCM1_HUMAN

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CRCM1_HUMAN
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CRCM1_HUMAN
θ value	8.63019e-144 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

CRCM1_MOUSE
θ value	2.69525e-129 (rank : 2)	NC score	0.998419 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWG9, Q8BUD4, Q8R586	Gene names	Tmem142a, Cracm1, Orai1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

ORAI2_MOUSE
θ value	3.44927e-84 (rank : 3)	NC score	0.987826 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH10, Q8C953	Gene names	Tmem142b, Orai2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B).

ORAI3_MOUSE
θ value	2.23575e-83 (rank : 4)	NC score	0.982305 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

ORAI2_HUMAN
θ value	3.81361e-83 (rank : 5)	NC score	0.987877 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SN7	Gene names	TMEM142B, C7orf19, CBCIP2, ORAI2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B) (CAP-binding protein complex-interacting protein 2).

ORAI3_HUMAN
θ value	2.73302e-81 (rank : 6)	NC score	0.986619 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRQ5, Q96BI8	Gene names	TMEM142C, ORAI3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

CX022_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.071042 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

SIAH2_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.014276 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

JIP3_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.008546 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TMPSD_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.001889 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

VEGFB_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.012366 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P49765, Q16528	Gene names	VEGFB, VRF
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

WDR46_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.011223 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ATX2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.007170 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	445	Shared Neighborhood Hits	2
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

PER1_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.006281 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

Hits sorted by NC score

CRCM1_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.63019e-144 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

CRCM1_MOUSE
NC score	0.998419 (rank : 2)	θ value	2.69525e-129 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWG9, Q8BUD4, Q8R586	Gene names	Tmem142a, Cracm1, Orai1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

ORAI2_HUMAN
NC score	0.987877 (rank : 3)	θ value	3.81361e-83 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SN7	Gene names	TMEM142B, C7orf19, CBCIP2, ORAI2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B) (CAP-binding protein complex-interacting protein 2).

ORAI2_MOUSE
NC score	0.987826 (rank : 4)	θ value	3.44927e-84 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH10, Q8C953	Gene names	Tmem142b, Orai2
Domain Architecture	No domain graphic available
Description	Protein orai-2 (Transmembrane protein 142B).

ORAI3_HUMAN
NC score	0.986619 (rank : 5)	θ value	2.73302e-81 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRQ5, Q96BI8	Gene names	TMEM142C, ORAI3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

ORAI3_MOUSE
NC score	0.982305 (rank : 6)	θ value	2.23575e-83 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8G8	Gene names	Tmem142c, Orai3
Domain Architecture	No domain graphic available
Description	Protein orai-3 (Transmembrane protein 142C).

CX022_HUMAN
NC score	0.071042 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

SIAH2_HUMAN
NC score	0.014276 (rank : 8)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

VEGFB_HUMAN
NC score	0.012366 (rank : 9)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P49765, Q16528	Gene names	VEGFB, VRF
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

WDR46_MOUSE
NC score	0.011223 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

JIP3_HUMAN
NC score	0.008546 (rank : 11)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

ATX2_MOUSE
NC score	0.007170 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	445	Shared Neighborhood Hits	2
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

PER1_MOUSE
NC score	0.006281 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

TMPSD_HUMAN
NC score	0.001889 (rank : 14)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).