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Network neighborhood for query Sequence : NPM_MOUSE

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NPM_MOUSE
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NPM_MOUSE
θ value	2.51683e-135 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

NPM_HUMAN
θ value	1.5801e-129 (rank : 2)	NC score	0.969446 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

NPM3_HUMAN
θ value	1.02238e-19 (rank : 3)	NC score	0.778300 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O75607, Q9UNY6	Gene names	NPM3
Domain Architecture
Description	Nucleoplasmin-3.

NPM3_MOUSE
θ value	3.28887e-18 (rank : 4)	NC score	0.772442 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CPP0, Q3UJ58	Gene names	Npm3
Domain Architecture
Description	Nucleoplasmin-3.

NPM2_MOUSE
θ value	1.58096e-12 (rank : 5)	NC score	0.677524 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

NPM2_HUMAN
θ value	3.89403e-11 (rank : 6)	NC score	0.659379 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SE8	Gene names	NPM2
Domain Architecture
Description	Nucleoplasmin-2.

LEO1_MOUSE
θ value	0.0113563 (rank : 7)	NC score	0.083353 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TRDN_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.090618 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

DPOD3_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.074446 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

HUWE1_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.039361 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

AKA12_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.072682 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

H15_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.074720 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

TCAL5_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.056288 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	806	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CC47_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.052614 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

OXR1_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.048844 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	516	Shared Neighborhood Hits	17
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

ATBF1_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.019051 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BLNK_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.038282 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

MAP9_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.036690 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	518	Shared Neighborhood Hits	14
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NFH_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.028933 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	1242	Shared Neighborhood Hits	34
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SMRC1_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.054441 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

VPS72_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.089416 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

DRD1_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.006344 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	P21728, Q4QRJ0	Gene names	DRD1
Domain Architecture
Description	D(1A) dopamine receptor.

NOL8_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.051106 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	297	Shared Neighborhood Hits	17
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

RBM25_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.034270 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	682	Shared Neighborhood Hits	16
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

LEO1_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.079248 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAP2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.041469 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

TOP2A_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.033547 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TXND2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.062381 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	793	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VPS72_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.082808 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

LYAR_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.052700 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

MYST4_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.033234 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RL1D1_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.055450 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SMRC1_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.050552 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TGM5_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.015896 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

CKAP2_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.035667 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

DZIP1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.027012 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	675	Shared Neighborhood Hits	8
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

PHF2_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.022019 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

POT15_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.017504 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	893	Shared Neighborhood Hits	17
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

H14_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.061302 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

SRRM2_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.032644 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ARHG3_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.013759 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

BRDT_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.020456 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

OXRP_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.027751 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	544	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RBM19_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.023455 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RECQ5_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.023065 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

AHI1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.009816 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	537	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

B3A3_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.019205 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CYLC1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.061104 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	24
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

H14_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.050015 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	P43274	Gene names	Hist1h1e, H1f4
Domain Architecture
Description	Histone H1.4 (H1 VAR.2) (H1e).

PARG_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.036720 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

RYR1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.019497 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

THOC2_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.049377 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	337	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

AFF4_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.039807 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

B3A3_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.017595 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

MAP1B_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.038345 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	977	Shared Neighborhood Hits	30
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PB1_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.016257 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

RBBP6_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.053777 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ZN592_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.005942 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	768	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

AFF4_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.045488 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	581	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANR21_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.012917 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	864	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

FANCM_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.013620 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

H10_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.055618 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

LYAR_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.036584 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

MSPD2_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.018495 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHP6, Q8N3H2, Q8NA83	Gene names	MOSPD2
Domain Architecture	No domain graphic available
Description	Motile sperm domain-containing protein 2.

P80C_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.023977 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

RFC1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.022899 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	352	Shared Neighborhood Hits	19
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SETD2_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.018509 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	412	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SYNG_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.013669 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TXND2_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.064685 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

IWS1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.055541 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.051490 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	1258	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

Hits sorted by NC score

NPM_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.51683e-135 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

NPM_HUMAN
NC score	0.969446 (rank : 2)	θ value	1.5801e-129 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

NPM3_HUMAN
NC score	0.778300 (rank : 3)	θ value	1.02238e-19 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O75607, Q9UNY6	Gene names	NPM3
Domain Architecture
Description	Nucleoplasmin-3.

NPM3_MOUSE
NC score	0.772442 (rank : 4)	θ value	3.28887e-18 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CPP0, Q3UJ58	Gene names	Npm3
Domain Architecture
Description	Nucleoplasmin-3.

NPM2_MOUSE
NC score	0.677524 (rank : 5)	θ value	1.58096e-12 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

NPM2_HUMAN
NC score	0.659379 (rank : 6)	θ value	3.89403e-11 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SE8	Gene names	NPM2
Domain Architecture
Description	Nucleoplasmin-2.

TRDN_HUMAN
NC score	0.090618 (rank : 7)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

VPS72_MOUSE
NC score	0.089416 (rank : 8)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

LEO1_MOUSE
NC score	0.083353 (rank : 9)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

VPS72_HUMAN
NC score	0.082808 (rank : 10)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

LEO1_HUMAN
NC score	0.079248 (rank : 11)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

H15_HUMAN
NC score	0.074720 (rank : 12)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

DPOD3_HUMAN
NC score	0.074446 (rank : 13)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

AKA12_HUMAN
NC score	0.072682 (rank : 14)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TXND2_MOUSE
NC score	0.064685 (rank : 15)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TXND2_HUMAN
NC score	0.062381 (rank : 16)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	793	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

H14_HUMAN
NC score	0.061302 (rank : 17)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

CYLC1_HUMAN
NC score	0.061104 (rank : 18)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	24
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TCAL5_HUMAN
NC score	0.056288 (rank : 19)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	806	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

H10_HUMAN
NC score	0.055618 (rank : 20)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

IWS1_HUMAN
NC score	0.055541 (rank : 21)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RL1D1_HUMAN
NC score	0.055450 (rank : 22)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SMRC1_HUMAN
NC score	0.054441 (rank : 23)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	18
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

RBBP6_HUMAN
NC score	0.053777 (rank : 24)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

LYAR_MOUSE
NC score	0.052700 (rank : 25)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CC47_MOUSE
NC score	0.052614 (rank : 26)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

IWS1_MOUSE
NC score	0.051490 (rank : 27)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	1258	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NOL8_HUMAN
NC score	0.051106 (rank : 28)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	297	Shared Neighborhood Hits	17
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

SMRC1_MOUSE
NC score	0.050552 (rank : 29)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

H14_MOUSE
NC score	0.050015 (rank : 30)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	P43274	Gene names	Hist1h1e, H1f4
Domain Architecture
Description	Histone H1.4 (H1 VAR.2) (H1e).

THOC2_HUMAN
NC score	0.049377 (rank : 31)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	337	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

OXR1_MOUSE
NC score	0.048844 (rank : 32)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	516	Shared Neighborhood Hits	17
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

AFF4_MOUSE
NC score	0.045488 (rank : 33)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	581	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MAP2_HUMAN
NC score	0.041469 (rank : 34)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

AFF4_HUMAN
NC score	0.039807 (rank : 35)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

HUWE1_HUMAN
NC score	0.039361 (rank : 36)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

MAP1B_MOUSE
NC score	0.038345 (rank : 37)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	977	Shared Neighborhood Hits	30
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BLNK_MOUSE
NC score	0.038282 (rank : 38)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

PARG_HUMAN
NC score	0.036720 (rank : 39)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

MAP9_HUMAN
NC score	0.036690 (rank : 40)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	518	Shared Neighborhood Hits	14
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

LYAR_HUMAN
NC score	0.036584 (rank : 41)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CKAP2_MOUSE
NC score	0.035667 (rank : 42)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

RBM25_HUMAN
NC score	0.034270 (rank : 43)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	682	Shared Neighborhood Hits	16
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TOP2A_MOUSE
NC score	0.033547 (rank : 44)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

MYST4_MOUSE
NC score	0.033234 (rank : 45)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	416	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SRRM2_MOUSE
NC score	0.032644 (rank : 46)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_HUMAN
NC score	0.028933 (rank : 47)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	1242	Shared Neighborhood Hits	34
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OXRP_HUMAN
NC score	0.027751 (rank : 48)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	544	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

DZIP1_HUMAN
NC score	0.027012 (rank : 49)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	675	Shared Neighborhood Hits	8
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

P80C_HUMAN
NC score	0.023977 (rank : 50)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

RBM19_MOUSE
NC score	0.023455 (rank : 51)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RECQ5_HUMAN
NC score	0.023065 (rank : 52)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RFC1_HUMAN
NC score	0.022899 (rank : 53)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	352	Shared Neighborhood Hits	19
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

PHF2_MOUSE
NC score	0.022019 (rank : 54)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

BRDT_HUMAN
NC score	0.020456 (rank : 55)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

RYR1_HUMAN
NC score	0.019497 (rank : 56)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

B3A3_HUMAN
NC score	0.019205 (rank : 57)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

ATBF1_MOUSE
NC score	0.019051 (rank : 58)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SETD2_HUMAN
NC score	0.018509 (rank : 59)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	412	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

MSPD2_HUMAN
NC score	0.018495 (rank : 60)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHP6, Q8N3H2, Q8NA83	Gene names	MOSPD2
Domain Architecture	No domain graphic available
Description	Motile sperm domain-containing protein 2.

B3A3_MOUSE
NC score	0.017595 (rank : 61)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

POT15_HUMAN
NC score	0.017504 (rank : 62)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	893	Shared Neighborhood Hits	17
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PB1_HUMAN
NC score	0.016257 (rank : 63)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TGM5_HUMAN
NC score	0.015896 (rank : 64)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

ARHG3_MOUSE
NC score	0.013759 (rank : 65)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

SYNG_MOUSE
NC score	0.013669 (rank : 66)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

FANCM_MOUSE
NC score	0.013620 (rank : 67)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

ANR21_HUMAN
NC score	0.012917 (rank : 68)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	864	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

AHI1_HUMAN
NC score	0.009816 (rank : 69)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	537	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

DRD1_HUMAN
NC score	0.006344 (rank : 70)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	P21728, Q4QRJ0	Gene names	DRD1
Domain Architecture
Description	D(1A) dopamine receptor.

ZN592_MOUSE
NC score	0.005942 (rank : 71)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	768	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).