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Network neighborhood for query Sequence : NFIA_MOUSE

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NFIA_MOUSE
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NFIA_HUMAN
θ value	0 (rank : 1)	NC score	0.998850 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	65	Shared Neighborhood Hits	60
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_HUMAN
θ value	5.18743e-173 (rank : 3)	NC score	0.987054 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q14938, O60413, Q12859, Q13050, Q13052, Q9UPH1, Q9Y6R8	Gene names	NFIX
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_MOUSE
θ value	1.78703e-165 (rank : 4)	NC score	0.986787 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	P70257, O08519, P70258, Q64192, Q99L78, Q9R1G2	Gene names	Nfix
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_MOUSE
θ value	5.59392e-143 (rank : 5)	NC score	0.974751 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIC_HUMAN
θ value	1.37783e-141 (rank : 6)	NC score	0.977487 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIC_MOUSE
θ value	1.99421e-132 (rank : 7)	NC score	0.974472 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P70255, O09072, P70256, Q3U2I9, Q99MA3, Q99MA4, Q99MA5, Q99MA6, Q99MA7, Q99MA8, Q9R1G3	Gene names	Nfic
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_HUMAN
θ value	9.26343e-130 (rank : 8)	NC score	0.977337 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

CJ108_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.124195 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

K1543_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.067003 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LATS1_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.008530 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	1057	Shared Neighborhood Hits	16
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

ZIMP7_MOUSE
θ value	0.125558 (rank : 12)	NC score	0.034437 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BAI2_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.030361 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.027944 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CIC_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.036575 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	992	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PZRN3_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.019047 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TAB2_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.038765 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

PCLO_MOUSE
θ value	0.47712 (rank : 18)	NC score	0.027300 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SSBP4_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.024249 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	753	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CT075_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.012856 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

SOX13_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.024745 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	464	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

GCP6_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.029894 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

ITSN1_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.010324 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	1669	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ULK1_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.005051 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	1214	Shared Neighborhood Hits	16
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ANR11_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.018552 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BCL9_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.037028 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	1008	Shared Neighborhood Hits	32
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CNTRB_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.010807 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	1029	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

IF4B_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.031913 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	368	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

NACAM_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.030374 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	1866	Shared Neighborhood Hits	40
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.033858 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	1202	Shared Neighborhood Hits	36
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PTN23_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.016711 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	726	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BSN_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.039612 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	2057	Shared Neighborhood Hits	44
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CRTC1_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.037112 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	319	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

E41LB_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.010116 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

K0310_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.035577 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LR37A_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.015410 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

GGA2_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.019328 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

PSL1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.020063 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

REN3A_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.031138 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	248	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

SRC8_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.016702 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

DPOLB_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.035969 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K409, Q3UAB6, Q922Z7	Gene names	Polb
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

BAZ2A_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.016429 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	744	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CIC_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.028684 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	742	Shared Neighborhood Hits	31
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DDX23_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.006401 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	486	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

JIP2_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.022312 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TP53B_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.019922 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	644	Shared Neighborhood Hits	17
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DDX55_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.006966 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DPOLB_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.022276 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P06746, Q6FI34	Gene names	POLB
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

MDC1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.017305 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

OTP_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.005146 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

SASH1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.016891 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	15
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SRRM1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.022815 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	966	Shared Neighborhood Hits	30
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ASPP2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.006363 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	1156	Shared Neighborhood Hits	18
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

EPN3_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.013468 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

NCF4_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.012435 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

P3C2A_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.007269 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PDZD2_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.018390 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ACAD8_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.004210 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7B6, Q8BK36, Q8BKQ8, Q8CFY9, Q9D2L8	Gene names	Acad8
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 8, mitochondrial precursor (EC 1.3.99.-) (ACAD-8) (Isobutyryl-CoA dehydrogenase).

AF10_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.005104 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

IF3A_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.007591 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	875	Shared Neighborhood Hits	10
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.007639 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	871	Shared Neighborhood Hits	11
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF4B_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.018327 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MSX2_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.002684 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	345	Shared Neighborhood Hits	5
SwissProt Accessions	Q03358, Q63856	Gene names	Msx2, Hox-8.1, Msx-2
Domain Architecture
Description	Homeobox protein MSX-2 (Hox-8.1).

MYO15_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.003976 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NHS_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.013816 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NUMBL_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.010363 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

SOX30_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.016671 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	305	Shared Neighborhood Hits	17
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX7_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.010681 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

TM1L1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.011817 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

Hits sorted by NC score

NFIA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIA_HUMAN
NC score	0.998850 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	65	Shared Neighborhood Hits	60
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_HUMAN
NC score	0.987054 (rank : 3)	θ value	5.18743e-173 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q14938, O60413, Q12859, Q13050, Q13052, Q9UPH1, Q9Y6R8	Gene names	NFIX
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_MOUSE
NC score	0.986787 (rank : 4)	θ value	1.78703e-165 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	P70257, O08519, P70258, Q64192, Q99L78, Q9R1G2	Gene names	Nfix
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIC_HUMAN
NC score	0.977487 (rank : 5)	θ value	1.37783e-141 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_HUMAN
NC score	0.977337 (rank : 6)	θ value	9.26343e-130 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	14
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIB_MOUSE
NC score	0.974751 (rank : 7)	θ value	5.59392e-143 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIC_MOUSE
NC score	0.974472 (rank : 8)	θ value	1.99421e-132 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P70255, O09072, P70256, Q3U2I9, Q99MA3, Q99MA4, Q99MA5, Q99MA6, Q99MA7, Q99MA8, Q9R1G3	Gene names	Nfic
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

CJ108_HUMAN
NC score	0.124195 (rank : 9)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

K1543_HUMAN
NC score	0.067003 (rank : 10)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BSN_MOUSE
NC score	0.039612 (rank : 11)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	2057	Shared Neighborhood Hits	44
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

TAB2_MOUSE
NC score	0.038765 (rank : 12)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

CRTC1_HUMAN
NC score	0.037112 (rank : 13)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	319	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

BCL9_HUMAN
NC score	0.037028 (rank : 14)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	1008	Shared Neighborhood Hits	32
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CIC_HUMAN
NC score	0.036575 (rank : 15)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	992	Shared Neighborhood Hits	33
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DPOLB_MOUSE
NC score	0.035969 (rank : 16)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K409, Q3UAB6, Q922Z7	Gene names	Polb
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

K0310_HUMAN
NC score	0.035577 (rank : 17)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

ZIMP7_MOUSE
NC score	0.034437 (rank : 18)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

NCOA6_HUMAN
NC score	0.033858 (rank : 19)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	1202	Shared Neighborhood Hits	36
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

IF4B_MOUSE
NC score	0.031913 (rank : 20)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	368	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

REN3A_HUMAN
NC score	0.031138 (rank : 21)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	248	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

NACAM_MOUSE
NC score	0.030374 (rank : 22)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	1866	Shared Neighborhood Hits	40
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BAI2_HUMAN
NC score	0.030361 (rank : 23)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

GCP6_HUMAN
NC score	0.029894 (rank : 24)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

CIC_MOUSE
NC score	0.028684 (rank : 25)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	742	Shared Neighborhood Hits	31
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BAI2_MOUSE
NC score	0.027944 (rank : 26)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

PCLO_MOUSE
NC score	0.027300 (rank : 27)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SOX13_HUMAN
NC score	0.024745 (rank : 28)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	464	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SSBP4_HUMAN
NC score	0.024249 (rank : 29)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	753	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SRRM1_MOUSE
NC score	0.022815 (rank : 30)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	966	Shared Neighborhood Hits	30
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

JIP2_HUMAN
NC score	0.022312 (rank : 31)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

DPOLB_HUMAN
NC score	0.022276 (rank : 32)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P06746, Q6FI34	Gene names	POLB
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

PSL1_HUMAN
NC score	0.020063 (rank : 33)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TP53B_MOUSE
NC score	0.019922 (rank : 34)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	644	Shared Neighborhood Hits	17
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GGA2_HUMAN
NC score	0.019328 (rank : 35)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

PZRN3_HUMAN
NC score	0.019047 (rank : 36)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ANR11_HUMAN
NC score	0.018552 (rank : 37)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PDZD2_HUMAN
NC score	0.018390 (rank : 38)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

IF4B_HUMAN
NC score	0.018327 (rank : 39)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MDC1_MOUSE
NC score	0.017305 (rank : 40)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SASH1_HUMAN
NC score	0.016891 (rank : 41)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	15
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

PTN23_MOUSE
NC score	0.016711 (rank : 42)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	726	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SRC8_MOUSE
NC score	0.016702 (rank : 43)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SOX30_HUMAN
NC score	0.016671 (rank : 44)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	305	Shared Neighborhood Hits	17
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

BAZ2A_MOUSE
NC score	0.016429 (rank : 45)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	744	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

LR37A_HUMAN
NC score	0.015410 (rank : 46)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NHS_HUMAN
NC score	0.013816 (rank : 47)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

EPN3_MOUSE
NC score	0.013468 (rank : 48)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CT075_MOUSE
NC score	0.012856 (rank : 49)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

NCF4_MOUSE
NC score	0.012435 (rank : 50)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

TM1L1_MOUSE
NC score	0.011817 (rank : 51)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

CNTRB_MOUSE
NC score	0.010807 (rank : 52)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	1029	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

SOX7_MOUSE
NC score	0.010681 (rank : 53)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

NUMBL_HUMAN
NC score	0.010363 (rank : 54)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

ITSN1_MOUSE
NC score	0.010324 (rank : 55)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	1669	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

E41LB_HUMAN
NC score	0.010116 (rank : 56)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

LATS1_HUMAN
NC score	0.008530 (rank : 57)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	1057	Shared Neighborhood Hits	16
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

IF3A_MOUSE
NC score	0.007639 (rank : 58)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	871	Shared Neighborhood Hits	11
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF3A_HUMAN
NC score	0.007591 (rank : 59)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	875	Shared Neighborhood Hits	10
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

P3C2A_MOUSE
NC score	0.007269 (rank : 60)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

DDX55_HUMAN
NC score	0.006966 (rank : 61)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX23_HUMAN
NC score	0.006401 (rank : 62)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	486	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

ASPP2_HUMAN
NC score	0.006363 (rank : 63)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	1156	Shared Neighborhood Hits	18
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

OTP_MOUSE
NC score	0.005146 (rank : 64)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

AF10_HUMAN
NC score	0.005104 (rank : 65)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

ULK1_MOUSE
NC score	0.005051 (rank : 66)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	1214	Shared Neighborhood Hits	16
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ACAD8_MOUSE
NC score	0.004210 (rank : 67)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7B6, Q8BK36, Q8BKQ8, Q8CFY9, Q9D2L8	Gene names	Acad8
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 8, mitochondrial precursor (EC 1.3.99.-) (ACAD-8) (Isobutyryl-CoA dehydrogenase).

MYO15_HUMAN
NC score	0.003976 (rank : 68)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MSX2_MOUSE
NC score	0.002684 (rank : 69)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	345	Shared Neighborhood Hits	5
SwissProt Accessions	Q03358, Q63856	Gene names	Msx2, Hox-8.1, Msx-2
Domain Architecture
Description	Homeobox protein MSX-2 (Hox-8.1).