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Network neighborhood for query Sequence : LAX1_HUMAN

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LAX1_HUMAN
SwissProt Accessions	Q8IWV1, Q6NSZ6, Q9NXB4	Gene names	LAX1, LAX
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LAX1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWV1, Q6NSZ6, Q9NXB4	Gene names	LAX1, LAX
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

LAX1_MOUSE
θ value	3.22093e-90 (rank : 2)	NC score	0.946630 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

APC_MOUSE
θ value	0.21417 (rank : 3)	NC score	0.055089 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

RBM13_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.077722 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY0, Q5U5T1, Q86UC4, Q96SY6	Gene names	RBM13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13) (NNP78).

SDCG1_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.053825 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

PGCA_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.013137 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CUTL2_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.017457 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DSPP_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.016657 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	645	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RERE_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.023822 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	785	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

E2AK4_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.005230 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1012	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

HPS3_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.036725 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

SOX6_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.012185 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

CCD16_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.021520 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CD86_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.029766 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

HPS3_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.034848 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

RERE_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.022166 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SET1A_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.014944 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	690	Shared Neighborhood Hits	7
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TAU_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.022169 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.025596 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

AT10B_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.007265 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

JIP2_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.014054 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TAF1C_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.020096 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

Hits sorted by NC score

LAX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWV1, Q6NSZ6, Q9NXB4	Gene names	LAX1, LAX
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

LAX1_MOUSE
NC score	0.946630 (rank : 2)	θ value	3.22093e-90 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB3, Q8BS18, Q8CGV1	Gene names	Lax1, Lax
Domain Architecture	No domain graphic available
Description	Lymphocyte transmembrane adapter 1 (Membrane-associated adapter protein LAX) (Linker for activation of X cells).

RBM13_HUMAN
NC score	0.077722 (rank : 3)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY0, Q5U5T1, Q86UC4, Q96SY6	Gene names	RBM13
Domain Architecture	No domain graphic available
Description	MAK16-like protein RBM13 (RNA-binding motif protein 13) (NNP78).

APC_MOUSE
NC score	0.055089 (rank : 4)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SDCG1_HUMAN
NC score	0.053825 (rank : 5)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

HPS3_MOUSE
NC score	0.036725 (rank : 6)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VB4, Q8VDX2, Q8VHT1	Gene names	Hps3, Coa
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein homolog (Cocoa protein).

HPS3_HUMAN
NC score	0.034848 (rank : 7)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

CD86_HUMAN
NC score	0.029766 (rank : 8)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

TAU_MOUSE
NC score	0.025596 (rank : 9)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RERE_MOUSE
NC score	0.023822 (rank : 10)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	785	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TAU_HUMAN
NC score	0.022169 (rank : 11)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RERE_HUMAN
NC score	0.022166 (rank : 12)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CCD16_HUMAN
NC score	0.021520 (rank : 13)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

TAF1C_HUMAN
NC score	0.020096 (rank : 14)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

CUTL2_HUMAN
NC score	0.017457 (rank : 15)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DSPP_HUMAN
NC score	0.016657 (rank : 16)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	645	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SET1A_HUMAN
NC score	0.014944 (rank : 17)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	690	Shared Neighborhood Hits	7
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

JIP2_MOUSE
NC score	0.014054 (rank : 18)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PGCA_HUMAN
NC score	0.013137 (rank : 19)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SOX6_HUMAN
NC score	0.012185 (rank : 20)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

AT10B_HUMAN
NC score	0.007265 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

E2AK4_HUMAN
NC score	0.005230 (rank : 22)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	1012	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).