Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : INP5E_MOUSE

For an explanation of this page, click here

INP5E_MOUSE
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

INP5E_HUMAN
θ value	0 (rank : 1)	NC score	0.949204 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

INP5E_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

SYNJ2_HUMAN
θ value	2.67802e-36 (rank : 3)	NC score	0.764516 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ2_MOUSE
θ value	5.0505e-35 (rank : 4)	NC score	0.768794 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ1_HUMAN
θ value	8.06329e-33 (rank : 5)	NC score	0.698419 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	1.79631e-32 (rank : 6)	NC score	0.698932 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

I5P2_HUMAN
θ value	5.22648e-32 (rank : 7)	NC score	0.737969 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	5.59698e-26 (rank : 8)	NC score	0.734694 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

PI5PA_HUMAN
θ value	1.5242e-23 (rank : 9)	NC score	0.641646 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	749	Shared Neighborhood Hits	32
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_MOUSE
θ value	1.6852e-22 (rank : 10)	NC score	0.704840 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SKIP_HUMAN
θ value	1.5773e-20 (rank : 11)	NC score	0.761935 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BT40, Q15733, Q9NPJ5, Q9P2R5	Gene names	SKIP, PPS
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

SKIP_MOUSE
θ value	3.51386e-20 (rank : 12)	NC score	0.758814 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5L6, O09040	Gene names	Skip, Pps
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

BCL9_HUMAN
θ value	0.00228821 (rank : 13)	NC score	0.110288 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	0.00298849 (rank : 14)	NC score	0.108554 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	770	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MKL1_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.055457 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	667	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PO121_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.059007 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

FOXQ1_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.019025 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

CBP_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.055700 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	941	Shared Neighborhood Hits	25
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.066948 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	1051	Shared Neighborhood Hits	32
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GTSE1_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.048951 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

I5P1_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.206197 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q14642, Q14640	Gene names	INPP5A
Domain Architecture
Description	Type I inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.56) (5PTase).

SYN2_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.031383 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TAU_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.031198 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	448	Shared Neighborhood Hits	13
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BAT2_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.059464 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NFIC_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.018125 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

CHD1_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.009773 (rank : 70)
Query Neighborhood Hits	59	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

PRDM2_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.015401 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PYGO2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.036105 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

BAG3_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.031776 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	513	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BANK1_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.023975 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

CJ047_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.033082 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

FA47A_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.054598 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	451	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NCOA3_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.013545 (rank : 64)
Query Neighborhood Hits	59	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

PME17_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.026389 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

M3K12_HUMAN
θ value	3.0926 (rank : 35)	NC score	-0.000264 (rank : 75)
Query Neighborhood Hits	59	Target Neighborhood Hits	940	Shared Neighborhood Hits	3
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

YLPM1_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.034559 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	670	Shared Neighborhood Hits	20
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

NRG2_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.014845 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PHLB1_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.017157 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	678	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRB3_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.033730 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RAPH1_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.029724 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	593	Shared Neighborhood Hits	20
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SEM6B_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.011353 (rank : 69)
Query Neighborhood Hits	59	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

AMELX_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.029549 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

CIC_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.032413 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	992	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

NRG2_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.013404 (rank : 65)
Query Neighborhood Hits	59	Target Neighborhood Hits	392	Shared Neighborhood Hits	3
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

RB_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.012919 (rank : 68)
Query Neighborhood Hits	59	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

RTN2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.013288 (rank : 66)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

SRRM2_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.041186 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	1470	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CI066_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.022153 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

K1802_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.026279 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	1378	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL2_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.024957 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	1788	Shared Neighborhood Hits	29
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHLPP_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.005018 (rank : 72)
Query Neighborhood Hits	59	Target Neighborhood Hits	604	Shared Neighborhood Hits	9
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PO6F1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.003998 (rank : 74)
Query Neighborhood Hits	59	Target Neighborhood Hits	370	Shared Neighborhood Hits	3
SwissProt Accessions	Q14863	Gene names	POU6F1, BRN5, MPOU, TCFB1
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (mPOU homeobox protein) (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5 protein).

SON_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.026168 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	957	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR2F_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.022586 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

AN13B_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.004134 (rank : 73)
Query Neighborhood Hits	59	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CAC1A_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.006103 (rank : 71)
Query Neighborhood Hits	59	Target Neighborhood Hits	387	Shared Neighborhood Hits	12
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

PME17_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.020412 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

PRG4_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.017345 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	624	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TRI66_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.013272 (rank : 67)
Query Neighborhood Hits	59	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAT2_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.056162 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CF155_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.062606 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

CK024_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.065983 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO039_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.072030 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MDC1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.065736 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	1446	Shared Neighborhood Hits	36
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.071526 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	998	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.060329 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	975	Shared Neighborhood Hits	30
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NACAM_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.074213 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	1866	Shared Neighborhood Hits	37
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.060141 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRP2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.056081 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052477 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	460	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRRT3_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.079200 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.055964 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	1621	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SAC3_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.203257 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q92562, Q53H49, Q5TCS6	Gene names	SAC3, KIAA0274
Domain Architecture
Description	SAC domain-containing protein 3.

SAC3_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.204676 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

SON_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.052109 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

Hits sorted by NC score

INP5E_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

INP5E_HUMAN
NC score	0.949204 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

SYNJ2_MOUSE
NC score	0.768794 (rank : 3)	θ value	5.0505e-35 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SYNJ2_HUMAN
NC score	0.764516 (rank : 4)	θ value	2.67802e-36 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SKIP_HUMAN
NC score	0.761935 (rank : 5)	θ value	1.5773e-20 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BT40, Q15733, Q9NPJ5, Q9P2R5	Gene names	SKIP, PPS
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

SKIP_MOUSE
NC score	0.758814 (rank : 6)	θ value	3.51386e-20 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5L6, O09040	Gene names	Skip, Pps
Domain Architecture
Description	Skeletal muscle and kidney-enriched inositol phosphatase (EC 3.1.3.56).

I5P2_HUMAN
NC score	0.737969 (rank : 7)	θ value	5.22648e-32 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.734694 (rank : 8)	θ value	5.59698e-26 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

PI5PA_MOUSE
NC score	0.704840 (rank : 9)	θ value	1.6852e-22 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SYNJ1_MOUSE
NC score	0.698932 (rank : 10)	θ value	1.79631e-32 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_HUMAN
NC score	0.698419 (rank : 11)	θ value	8.06329e-33 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PI5PA_HUMAN
NC score	0.641646 (rank : 12)	θ value	1.5242e-23 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	749	Shared Neighborhood Hits	32
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

I5P1_HUMAN
NC score	0.206197 (rank : 13)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q14642, Q14640	Gene names	INPP5A
Domain Architecture
Description	Type I inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.56) (5PTase).

SAC3_MOUSE
NC score	0.204676 (rank : 14)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	59	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

SAC3_HUMAN
NC score	0.203257 (rank : 15)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	59	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q92562, Q53H49, Q5TCS6	Gene names	SAC3, KIAA0274
Domain Architecture
Description	SAC domain-containing protein 3.

BCL9_HUMAN
NC score	0.110288 (rank : 16)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
NC score	0.108554 (rank : 17)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	770	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PRRT3_HUMAN
NC score	0.079200 (rank : 18)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	59	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

NACAM_MOUSE
NC score	0.074213 (rank : 19)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	59	Target Neighborhood Hits	1866	Shared Neighborhood Hits	37
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CO039_MOUSE
NC score	0.072030 (rank : 20)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MDC1_MOUSE
NC score	0.071526 (rank : 21)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	59	Target Neighborhood Hits	998	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CBP_MOUSE
NC score	0.066948 (rank : 22)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	1051	Shared Neighborhood Hits	32
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CK024_HUMAN
NC score	0.065983 (rank : 23)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MDC1_HUMAN
NC score	0.065736 (rank : 24)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	59	Target Neighborhood Hits	1446	Shared Neighborhood Hits	36
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CF155_HUMAN
NC score	0.062606 (rank : 25)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

MUC1_HUMAN
NC score	0.060329 (rank : 26)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	59	Target Neighborhood Hits	975	Shared Neighborhood Hits	30
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OGFR_HUMAN
NC score	0.060141 (rank : 27)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	59	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BAT2_HUMAN
NC score	0.059464 (rank : 28)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PO121_HUMAN
NC score	0.059007 (rank : 29)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

BAT2_MOUSE
NC score	0.056162 (rank : 30)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRP2_MOUSE
NC score	0.056081 (rank : 31)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	59	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RGS3_MOUSE
NC score	0.055964 (rank : 32)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	59	Target Neighborhood Hits	1621	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CBP_HUMAN
NC score	0.055700 (rank : 33)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	941	Shared Neighborhood Hits	25
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MKL1_MOUSE
NC score	0.055457 (rank : 34)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	667	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

FA47A_HUMAN
NC score	0.054598 (rank : 35)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	451	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PRR12_HUMAN
NC score	0.052477 (rank : 36)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	59	Target Neighborhood Hits	460	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SON_HUMAN
NC score	0.052109 (rank : 37)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	59	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GTSE1_MOUSE
NC score	0.048951 (rank : 38)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SRRM2_MOUSE
NC score	0.041186 (rank : 39)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	1470	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PYGO2_HUMAN
NC score	0.036105 (rank : 40)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

YLPM1_HUMAN
NC score	0.034559 (rank : 41)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	670	Shared Neighborhood Hits	20
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PRB3_HUMAN
NC score	0.033730 (rank : 42)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CJ047_MOUSE
NC score	0.033082 (rank : 43)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

CIC_HUMAN
NC score	0.032413 (rank : 44)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	992	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BAG3_MOUSE
NC score	0.031776 (rank : 45)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	513	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SYN2_HUMAN
NC score	0.031383 (rank : 46)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TAU_HUMAN
NC score	0.031198 (rank : 47)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	448	Shared Neighborhood Hits	13
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RAPH1_HUMAN
NC score	0.029724 (rank : 48)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	593	Shared Neighborhood Hits	20
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AMELX_HUMAN
NC score	0.029549 (rank : 49)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

PME17_HUMAN
NC score	0.026389 (rank : 50)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

K1802_HUMAN
NC score	0.026279 (rank : 51)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	1378	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SON_MOUSE
NC score	0.026168 (rank : 52)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	957	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MLL2_HUMAN
NC score	0.024957 (rank : 53)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	1788	Shared Neighborhood Hits	29
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BANK1_MOUSE
NC score	0.023975 (rank : 54)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

SPR2F_HUMAN
NC score	0.022586 (rank : 55)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

CI066_HUMAN
NC score	0.022153 (rank : 56)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T8R8, Q96NB0	Gene names	C9orf66
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf66.

PME17_MOUSE
NC score	0.020412 (rank : 57)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

FOXQ1_HUMAN
NC score	0.019025 (rank : 58)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

NFIC_HUMAN
NC score	0.018125 (rank : 59)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P08651, P08652, Q14932, Q9UPJ3, Q9UPJ9, Q9UPK0, Q9UPK1	Gene names	NFIC, NFI
Domain Architecture
Description	Nuclear factor 1 C-type (Nuclear factor 1/C) (NF1-C) (NFI-C) (NF-I/C) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PRG4_MOUSE
NC score	0.017345 (rank : 60)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	624	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PHLB1_MOUSE
NC score	0.017157 (rank : 61)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	678	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRDM2_HUMAN
NC score	0.015401 (rank : 62)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

NRG2_HUMAN
NC score	0.014845 (rank : 63)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NCOA3_HUMAN
NC score	0.013545 (rank : 64)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NRG2_MOUSE
NC score	0.013404 (rank : 65)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	392	Shared Neighborhood Hits	3
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

RTN2_HUMAN
NC score	0.013288 (rank : 66)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

TRI66_MOUSE
NC score	0.013272 (rank : 67)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RB_MOUSE
NC score	0.012919 (rank : 68)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

SEM6B_HUMAN
NC score	0.011353 (rank : 69)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

CHD1_MOUSE
NC score	0.009773 (rank : 70)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CAC1A_HUMAN
NC score	0.006103 (rank : 71)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	387	Shared Neighborhood Hits	12
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

PHLPP_HUMAN
NC score	0.005018 (rank : 72)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	604	Shared Neighborhood Hits	9
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

AN13B_MOUSE
NC score	0.004134 (rank : 73)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

PO6F1_HUMAN
NC score	0.003998 (rank : 74)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	370	Shared Neighborhood Hits	3
SwissProt Accessions	Q14863	Gene names	POU6F1, BRN5, MPOU, TCFB1
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (mPOU homeobox protein) (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5 protein).

M3K12_HUMAN
NC score	-0.000264 (rank : 75)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	940	Shared Neighborhood Hits	3
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).