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Network neighborhood for query Sequence : IDH3A_HUMAN

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IDH3A_HUMAN
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IDH3A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3A_MOUSE
θ value	0 (rank : 2)	NC score	0.999519 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3B_HUMAN
θ value	8.51556e-75 (rank : 3)	NC score	0.957315 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	O43837, O95106, Q5JXS8, Q9NQ06, Q9NQ07, Q9UEX0, Q9UG99	Gene names	IDH3B
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3G_HUMAN
θ value	5.51964e-74 (rank : 4)	NC score	0.945976 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P51553, Q9BUU5	Gene names	IDH3G
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3G_MOUSE
θ value	1.60597e-73 (rank : 5)	NC score	0.947806 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	P70404	Gene names	Idh3g
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDHP_HUMAN
θ value	0.00298849 (rank : 6)	NC score	0.134761 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P48735, Q96GT3	Gene names	IDH2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDHP_MOUSE
θ value	0.00298849 (rank : 7)	NC score	0.132334 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54071, Q8C2R9, Q9EQK1	Gene names	Idh2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

TITIN_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.003215 (rank : 12)
Query Neighborhood Hits	10	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

APEX2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.014433 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

NPHN_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.005889 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

IDHC_HUMAN
θ value	θ > 10 (rank : 11)	NC score	0.059532 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O75874, Q93090, Q9NTJ9, Q9UKW8	Gene names	IDH1, PICD
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHC_MOUSE
θ value	θ > 10 (rank : 12)	NC score	0.059635 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O88844	Gene names	Idh1
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

Hits sorted by NC score

IDH3A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3A_MOUSE
NC score	0.999519 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3B_HUMAN
NC score	0.957315 (rank : 3)	θ value	8.51556e-75 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	O43837, O95106, Q5JXS8, Q9NQ06, Q9NQ07, Q9UEX0, Q9UG99	Gene names	IDH3B
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3G_MOUSE
NC score	0.947806 (rank : 4)	θ value	1.60597e-73 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	P70404	Gene names	Idh3g
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3G_HUMAN
NC score	0.945976 (rank : 5)	θ value	5.51964e-74 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P51553, Q9BUU5	Gene names	IDH3G
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDHP_HUMAN
NC score	0.134761 (rank : 6)	θ value	0.00298849 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P48735, Q96GT3	Gene names	IDH2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDHP_MOUSE
NC score	0.132334 (rank : 7)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54071, Q8C2R9, Q9EQK1	Gene names	Idh2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDHC_MOUSE
NC score	0.059635 (rank : 8)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	10	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O88844	Gene names	Idh1
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHC_HUMAN
NC score	0.059532 (rank : 9)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O75874, Q93090, Q9NTJ9, Q9UKW8	Gene names	IDH1, PICD
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

APEX2_HUMAN
NC score	0.014433 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

NPHN_HUMAN
NC score	0.005889 (rank : 11)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

TITIN_HUMAN
NC score	0.003215 (rank : 12)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	2923	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).