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Network neighborhood for query Sequence : IDHC_HUMAN

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IDHC_HUMAN
SwissProt Accessions	O75874, Q93090, Q9NTJ9, Q9UKW8	Gene names	IDH1, PICD
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IDHC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O75874, Q93090, Q9NTJ9, Q9UKW8	Gene names	IDH1, PICD
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHC_MOUSE
θ value	0 (rank : 2)	NC score	0.999913 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O88844	Gene names	Idh1
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHP_MOUSE
θ value	8.57033e-168 (rank : 3)	NC score	0.987506 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54071, Q8C2R9, Q9EQK1	Gene names	Idh2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDHP_HUMAN
θ value	9.47563e-167 (rank : 4)	NC score	0.988402 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P48735, Q96GT3	Gene names	IDH2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

METH_HUMAN
θ value	8.99809 (rank : 5)	NC score	0.027121 (rank : 7)
Query Neighborhood Hits	5	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99707, Q99713, Q99723	Gene names	MTR
Domain Architecture
Description	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate-- homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS).

IDH3A_HUMAN
θ value	θ > 10 (rank : 6)	NC score	0.059532 (rank : 6)
Query Neighborhood Hits	5	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3A_MOUSE
θ value	θ > 10 (rank : 7)	NC score	0.067237 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

Hits sorted by NC score

IDHC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O75874, Q93090, Q9NTJ9, Q9UKW8	Gene names	IDH1, PICD
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHC_MOUSE
NC score	0.999913 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	5	Target Neighborhood Hits	5	Shared Neighborhood Hits	5
SwissProt Accessions	O88844	Gene names	Idh1
Domain Architecture
Description	Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP).

IDHP_HUMAN
NC score	0.988402 (rank : 3)	θ value	9.47563e-167 (rank : 4)
Query Neighborhood Hits	5	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P48735, Q96GT3	Gene names	IDH2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDHP_MOUSE
NC score	0.987506 (rank : 4)	θ value	8.57033e-168 (rank : 3)
Query Neighborhood Hits	5	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P54071, Q8C2R9, Q9EQK1	Gene names	Idh2
Domain Architecture
Description	Isocitrate dehydrogenase [NADP], mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M).

IDH3A_MOUSE
NC score	0.067237 (rank : 5)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	5	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6R2, Q3UAM8, Q8C8A1, Q9D1L1	Gene names	Idh3a
Domain Architecture	No domain graphic available
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

IDH3A_HUMAN
NC score	0.059532 (rank : 6)	θ value	θ > 10 (rank : 6)
Query Neighborhood Hits	5	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P50213, Q9H3X0	Gene names	IDH3A
Domain Architecture
Description	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH).

METH_HUMAN
NC score	0.027121 (rank : 7)	θ value	8.99809 (rank : 5)
Query Neighborhood Hits	5	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99707, Q99713, Q99723	Gene names	MTR
Domain Architecture
Description	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate-- homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS).