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Network neighborhood for query Sequence : HSPB1_HUMAN

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HSPB1_HUMAN
SwissProt Accessions	P04792, Q6FI47, Q9UC31	Gene names	HSPB1, HSP27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDa protein) (28 kDa heat shock protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HSPB1_HUMAN
θ value	4.04623e-109 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P04792, Q6FI47, Q9UC31	Gene names	HSPB1, HSP27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDa protein) (28 kDa heat shock protein).

HSPB1_MOUSE
θ value	7.64859e-100 (rank : 2)	NC score	0.998002 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	P14602	Gene names	Hspb1, Hsp25, Hsp27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Growth-related 25 kDa protein) (P25) (HSP25).

CRYAB_MOUSE
θ value	2.05525e-28 (rank : 3)	NC score	0.915386 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P23927, Q64325	Gene names	Cryab, Crya2
Domain Architecture
Description	Alpha crystallin B chain (Alpha(B)-crystallin) (P23).

CRYAB_HUMAN
θ value	3.50572e-28 (rank : 4)	NC score	0.914142 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P02511, O43416	Gene names	CRYAB, CRYA2
Domain Architecture
Description	Alpha crystallin B chain (Alpha(B)-crystallin) (Rosenthal fiber component) (Heat-shock protein beta-5) (HspB5) (NY-REN-27 antigen).

HSPB8_MOUSE
θ value	2.35151e-24 (rank : 5)	NC score	0.885836 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

HSPB8_HUMAN
θ value	4.01107e-24 (rank : 6)	NC score	0.884172 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

CRYAA_HUMAN
θ value	1.16704e-23 (rank : 7)	NC score	0.892798 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P02489	Gene names	CRYAA, CRYA1, HSPB4
Domain Architecture
Description	Alpha crystallin A chain (Heat-shock protein beta-4) (HspB4) [Contains: Alpha crystallin A chain, short form].

CRYAA_MOUSE
θ value	1.86321e-21 (rank : 8)	NC score	0.880753 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P24622, P02490, P02496, P82532, Q61444, Q6LEL4	Gene names	Cryaa, Crya1
Domain Architecture
Description	Alpha crystallin A chain [Contains: Alpha crystallin A chain, short form].

HSPB2_HUMAN
θ value	7.0802e-21 (rank : 9)	NC score	0.880172 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q16082, Q6I9U7	Gene names	HSPB2
Domain Architecture
Description	Heat-shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP).

HSPB6_MOUSE
θ value	7.0802e-21 (rank : 10)	NC score	0.903509 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q5EBG6	Gene names	Hspb6
Domain Architecture	No domain graphic available
Description	Heat-shock protein beta-6 (HspB6).

HSPB2_MOUSE
θ value	7.82807e-20 (rank : 11)	NC score	0.880254 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PR8, Q9CZC2	Gene names	Hspb2
Domain Architecture
Description	Heat-shock protein beta-2 (HspB2).

HSPB6_HUMAN
θ value	3.88503e-19 (rank : 12)	NC score	0.901997 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O14558, O14551, Q6NVI3, Q96MG9	Gene names	HSPB6
Domain Architecture
Description	Heat-shock protein beta-6 (HspB6) (Heat-shock 20 kDa-like protein p20).

HSPB3_MOUSE
θ value	4.59992e-12 (rank : 13)	NC score	0.787139 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZ57, Q569N3	Gene names	Hspb3
Domain Architecture
Description	Heat-shock protein beta-3 (HspB3).

HSPB3_HUMAN
θ value	1.74796e-11 (rank : 14)	NC score	0.782303 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q12988	Gene names	HSPB3, HSPL27
Domain Architecture
Description	Heat-shock protein beta-3 (HspB3) (Heat shock 17 kDa protein).

HSPB7_HUMAN
θ value	3.41135e-07 (rank : 15)	NC score	0.661142 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBY9, Q9NU17	Gene names	HSPB7, CVHSP
Domain Architecture
Description	Heat-shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp).

HSPB7_MOUSE
θ value	2.88788e-06 (rank : 16)	NC score	0.644896 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	P35385, Q8CDI0, Q9QUS2	Gene names	Hspb7, Cvhsp, Hsp25-2
Domain Architecture
Description	Heat-shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) (Heat shock protein 25 kDa 2) (Protein p19/6.8).

HSPB9_MOUSE
θ value	0.000602161 (rank : 17)	NC score	0.485356 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DAM3	Gene names	Hspb9
Domain Architecture
Description	Heat-shock protein beta-9 (HspB9).

ODFP_HUMAN
θ value	0.000602161 (rank : 18)	NC score	0.245705 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

ODFP_MOUSE
θ value	0.000602161 (rank : 19)	NC score	0.237721 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

HSPB9_HUMAN
θ value	0.00509761 (rank : 20)	NC score	0.418419 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQS6, Q52LB4	Gene names	HSPB9
Domain Architecture
Description	Heat-shock protein beta-9 (HspB9).

AFAD_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.026511 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

K1802_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.005725 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	1596	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WBS14_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.021903 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

CBPN_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.010572 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

BIN1_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.007837 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

Hits sorted by NC score

HSPB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.04623e-109 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P04792, Q6FI47, Q9UC31	Gene names	HSPB1, HSP27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDa protein) (28 kDa heat shock protein).

HSPB1_MOUSE
NC score	0.998002 (rank : 2)	θ value	7.64859e-100 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	P14602	Gene names	Hspb1, Hsp25, Hsp27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Growth-related 25 kDa protein) (P25) (HSP25).

CRYAB_MOUSE
NC score	0.915386 (rank : 3)	θ value	2.05525e-28 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P23927, Q64325	Gene names	Cryab, Crya2
Domain Architecture
Description	Alpha crystallin B chain (Alpha(B)-crystallin) (P23).

CRYAB_HUMAN
NC score	0.914142 (rank : 4)	θ value	3.50572e-28 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P02511, O43416	Gene names	CRYAB, CRYA2
Domain Architecture
Description	Alpha crystallin B chain (Alpha(B)-crystallin) (Rosenthal fiber component) (Heat-shock protein beta-5) (HspB5) (NY-REN-27 antigen).

HSPB6_MOUSE
NC score	0.903509 (rank : 5)	θ value	7.0802e-21 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q5EBG6	Gene names	Hspb6
Domain Architecture	No domain graphic available
Description	Heat-shock protein beta-6 (HspB6).

HSPB6_HUMAN
NC score	0.901997 (rank : 6)	θ value	3.88503e-19 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O14558, O14551, Q6NVI3, Q96MG9	Gene names	HSPB6
Domain Architecture
Description	Heat-shock protein beta-6 (HspB6) (Heat-shock 20 kDa-like protein p20).

CRYAA_HUMAN
NC score	0.892798 (rank : 7)	θ value	1.16704e-23 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P02489	Gene names	CRYAA, CRYA1, HSPB4
Domain Architecture
Description	Alpha crystallin A chain (Heat-shock protein beta-4) (HspB4) [Contains: Alpha crystallin A chain, short form].

HSPB8_MOUSE
NC score	0.885836 (rank : 8)	θ value	2.35151e-24 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

HSPB8_HUMAN
NC score	0.884172 (rank : 9)	θ value	4.01107e-24 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

CRYAA_MOUSE
NC score	0.880753 (rank : 10)	θ value	1.86321e-21 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P24622, P02490, P02496, P82532, Q61444, Q6LEL4	Gene names	Cryaa, Crya1
Domain Architecture
Description	Alpha crystallin A chain [Contains: Alpha crystallin A chain, short form].

HSPB2_MOUSE
NC score	0.880254 (rank : 11)	θ value	7.82807e-20 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PR8, Q9CZC2	Gene names	Hspb2
Domain Architecture
Description	Heat-shock protein beta-2 (HspB2).

HSPB2_HUMAN
NC score	0.880172 (rank : 12)	θ value	7.0802e-21 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q16082, Q6I9U7	Gene names	HSPB2
Domain Architecture
Description	Heat-shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP).

HSPB3_MOUSE
NC score	0.787139 (rank : 13)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZ57, Q569N3	Gene names	Hspb3
Domain Architecture
Description	Heat-shock protein beta-3 (HspB3).

HSPB3_HUMAN
NC score	0.782303 (rank : 14)	θ value	1.74796e-11 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q12988	Gene names	HSPB3, HSPL27
Domain Architecture
Description	Heat-shock protein beta-3 (HspB3) (Heat shock 17 kDa protein).

HSPB7_HUMAN
NC score	0.661142 (rank : 15)	θ value	3.41135e-07 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBY9, Q9NU17	Gene names	HSPB7, CVHSP
Domain Architecture
Description	Heat-shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp).

HSPB7_MOUSE
NC score	0.644896 (rank : 16)	θ value	2.88788e-06 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	P35385, Q8CDI0, Q9QUS2	Gene names	Hspb7, Cvhsp, Hsp25-2
Domain Architecture
Description	Heat-shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) (Heat shock protein 25 kDa 2) (Protein p19/6.8).

HSPB9_MOUSE
NC score	0.485356 (rank : 17)	θ value	0.000602161 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DAM3	Gene names	Hspb9
Domain Architecture
Description	Heat-shock protein beta-9 (HspB9).

HSPB9_HUMAN
NC score	0.418419 (rank : 18)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQS6, Q52LB4	Gene names	HSPB9
Domain Architecture
Description	Heat-shock protein beta-9 (HspB9).

ODFP_HUMAN
NC score	0.245705 (rank : 19)	θ value	0.000602161 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

ODFP_MOUSE
NC score	0.237721 (rank : 20)	θ value	0.000602161 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

AFAD_HUMAN
NC score	0.026511 (rank : 21)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

WBS14_MOUSE
NC score	0.021903 (rank : 22)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

CBPN_MOUSE
NC score	0.010572 (rank : 23)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

BIN1_MOUSE
NC score	0.007837 (rank : 24)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

K1802_MOUSE
NC score	0.005725 (rank : 25)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	1596	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.