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Network neighborhood for query Sequence : GSDC1_HUMAN

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GSDC1_HUMAN
SwissProt Accessions	P57764, Q96Q98	Gene names	GSDMDC1, DFNA5L
Domain Architecture
Description	Gasdermin domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GSDC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P57764, Q96Q98	Gene names	GSDMDC1, DFNA5L
Domain Architecture
Description	Gasdermin domain-containing protein 1.

GSDC1_MOUSE
θ value	3.5201e-129 (rank : 2)	NC score	0.983234 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8T2, Q3TBD9	Gene names	Gsdmdc1
Domain Architecture	No domain graphic available
Description	Gasdermin domain-containing protein 1.

MLZE_HUMAN
θ value	3.85808e-43 (rank : 3)	NC score	0.864337 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYG8, Q5XKF3, Q6P494	Gene names	MLZE
Domain Architecture	No domain graphic available
Description	Melanoma-derived leucine zipper-containing extranuclear factor.

GSDM1_HUMAN
θ value	7.27602e-42 (rank : 4)	NC score	0.845893 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

GSDM1_MOUSE
θ value	3.4976e-36 (rank : 5)	NC score	0.843448 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

DFNA5_HUMAN
θ value	3.08544e-08 (rank : 6)	NC score	0.366210 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O60443, O14590, Q9UBV3	Gene names	DFNA5, ICERE1
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 (Inversely correlated with estrogen receptor expression 1) (ICERE-1).

DFNA5_MOUSE
θ value	8.97725e-08 (rank : 7)	NC score	0.377260 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2D3	Gene names	Dfna5, Dfna5h
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 homolog.

PJVK_MOUSE
θ value	3.77169e-06 (rank : 8)	NC score	0.417869 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q0ZLH2	Gene names	Pjvk, Dfnb59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein homolog).

PJVK_HUMAN
θ value	8.40245e-06 (rank : 9)	NC score	0.413498 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q0ZLH3	Gene names	PJVK, DFNB59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein).

SRMS_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.007543 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	946	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.006440 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	964	Shared Neighborhood Hits	3
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

BOLA1_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.054628 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8S9	Gene names	Bola1
Domain Architecture	No domain graphic available
Description	BolA-like protein 1.

BOLA1_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.049142 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3E2, Q5QNY0	Gene names	BOLA1
Domain Architecture
Description	BolA-like protein 1.

GALT4_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.004990 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N4A0, O00208	Gene names	GALNT4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).

LASS5_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.007916 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6K9, Q3UL17, Q80YB2, Q8BPH6, Q921T8, Q924Z3	Gene names	Lass5, Trh4
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5 (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4).

Hits sorted by NC score

GSDC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P57764, Q96Q98	Gene names	GSDMDC1, DFNA5L
Domain Architecture
Description	Gasdermin domain-containing protein 1.

GSDC1_MOUSE
NC score	0.983234 (rank : 2)	θ value	3.5201e-129 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8T2, Q3TBD9	Gene names	Gsdmdc1
Domain Architecture	No domain graphic available
Description	Gasdermin domain-containing protein 1.

MLZE_HUMAN
NC score	0.864337 (rank : 3)	θ value	3.85808e-43 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYG8, Q5XKF3, Q6P494	Gene names	MLZE
Domain Architecture	No domain graphic available
Description	Melanoma-derived leucine zipper-containing extranuclear factor.

GSDM1_HUMAN
NC score	0.845893 (rank : 4)	θ value	7.27602e-42 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

GSDM1_MOUSE
NC score	0.843448 (rank : 5)	θ value	3.4976e-36 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

PJVK_MOUSE
NC score	0.417869 (rank : 6)	θ value	3.77169e-06 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q0ZLH2	Gene names	Pjvk, Dfnb59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein homolog).

PJVK_HUMAN
NC score	0.413498 (rank : 7)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q0ZLH3	Gene names	PJVK, DFNB59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein).

DFNA5_MOUSE
NC score	0.377260 (rank : 8)	θ value	8.97725e-08 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2D3	Gene names	Dfna5, Dfna5h
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 homolog.

DFNA5_HUMAN
NC score	0.366210 (rank : 9)	θ value	3.08544e-08 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	O60443, O14590, Q9UBV3	Gene names	DFNA5, ICERE1
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 (Inversely correlated with estrogen receptor expression 1) (ICERE-1).

BOLA1_MOUSE
NC score	0.054628 (rank : 10)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8S9	Gene names	Bola1
Domain Architecture	No domain graphic available
Description	BolA-like protein 1.

BOLA1_HUMAN
NC score	0.049142 (rank : 11)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3E2, Q5QNY0	Gene names	BOLA1
Domain Architecture
Description	BolA-like protein 1.

LASS5_MOUSE
NC score	0.007916 (rank : 12)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6K9, Q3UL17, Q80YB2, Q8BPH6, Q921T8, Q924Z3	Gene names	Lass5, Trh4
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5 (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4).

SRMS_HUMAN
NC score	0.007543 (rank : 13)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	946	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
NC score	0.006440 (rank : 14)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	964	Shared Neighborhood Hits	3
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

GALT4_HUMAN
NC score	0.004990 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N4A0, O00208	Gene names	GALNT4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).