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Network neighborhood for query Sequence : DFNA5_HUMAN

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DFNA5_HUMAN
SwissProt Accessions	O60443, O14590, Q9UBV3	Gene names	DFNA5, ICERE1
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 (Inversely correlated with estrogen receptor expression 1) (ICERE-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DFNA5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O60443, O14590, Q9UBV3	Gene names	DFNA5, ICERE1
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 (Inversely correlated with estrogen receptor expression 1) (ICERE-1).

DFNA5_MOUSE
θ value	0 (rank : 2)	NC score	0.991652 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2D3	Gene names	Dfna5, Dfna5h
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 homolog.

PJVK_HUMAN
θ value	2.34606e-32 (rank : 3)	NC score	0.773615 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q0ZLH3	Gene names	PJVK, DFNB59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein).

PJVK_MOUSE
θ value	5.22648e-32 (rank : 4)	NC score	0.769255 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q0ZLH2	Gene names	Pjvk, Dfnb59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein homolog).

GSDC1_HUMAN
θ value	3.08544e-08 (rank : 5)	NC score	0.366210 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P57764, Q96Q98	Gene names	GSDMDC1, DFNA5L
Domain Architecture
Description	Gasdermin domain-containing protein 1.

GSDC1_MOUSE
θ value	1.29631e-06 (rank : 6)	NC score	0.318492 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8T2, Q3TBD9	Gene names	Gsdmdc1
Domain Architecture	No domain graphic available
Description	Gasdermin domain-containing protein 1.

CKAP5_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.032949 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

CE290_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.006627 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	1553	Shared Neighborhood Hits	3
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

FSTL5_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.010026 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	355	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

MYH8_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.002722 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	1600	Shared Neighborhood Hits	3
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PCLO_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.008293 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	2275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GSDM1_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.162901 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

GSDM1_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.159850 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

MLZE_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.128639 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYG8, Q5XKF3, Q6P494	Gene names	MLZE
Domain Architecture	No domain graphic available
Description	Melanoma-derived leucine zipper-containing extranuclear factor.

Hits sorted by NC score

DFNA5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O60443, O14590, Q9UBV3	Gene names	DFNA5, ICERE1
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 (Inversely correlated with estrogen receptor expression 1) (ICERE-1).

DFNA5_MOUSE
NC score	0.991652 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2D3	Gene names	Dfna5, Dfna5h
Domain Architecture
Description	Non-syndromic hearing impairment protein 5 homolog.

PJVK_HUMAN
NC score	0.773615 (rank : 3)	θ value	2.34606e-32 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q0ZLH3	Gene names	PJVK, DFNB59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein).

PJVK_MOUSE
NC score	0.769255 (rank : 4)	θ value	5.22648e-32 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q0ZLH2	Gene names	Pjvk, Dfnb59
Domain Architecture	No domain graphic available
Description	Pejvakin (Autosomal recessive deafness type 59 protein homolog).

GSDC1_HUMAN
NC score	0.366210 (rank : 5)	θ value	3.08544e-08 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P57764, Q96Q98	Gene names	GSDMDC1, DFNA5L
Domain Architecture
Description	Gasdermin domain-containing protein 1.

GSDC1_MOUSE
NC score	0.318492 (rank : 6)	θ value	1.29631e-06 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8T2, Q3TBD9	Gene names	Gsdmdc1
Domain Architecture	No domain graphic available
Description	Gasdermin domain-containing protein 1.

GSDM1_HUMAN
NC score	0.162901 (rank : 7)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

GSDM1_MOUSE
NC score	0.159850 (rank : 8)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EST1	Gene names	Gsdm1, Gsdm
Domain Architecture	No domain graphic available
Description	Gasdermin.

MLZE_HUMAN
NC score	0.128639 (rank : 9)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYG8, Q5XKF3, Q6P494	Gene names	MLZE
Domain Architecture	No domain graphic available
Description	Melanoma-derived leucine zipper-containing extranuclear factor.

CKAP5_HUMAN
NC score	0.032949 (rank : 10)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

FSTL5_MOUSE
NC score	0.010026 (rank : 11)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	355	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

PCLO_MOUSE
NC score	0.008293 (rank : 12)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	2275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CE290_HUMAN
NC score	0.006627 (rank : 13)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	1553	Shared Neighborhood Hits	3
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MYH8_MOUSE
NC score	0.002722 (rank : 14)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	1600	Shared Neighborhood Hits	3
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).