Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : GGPPS_HUMAN

For an explanation of this page, click here

GGPPS_HUMAN
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GGPPS_HUMAN
θ value	8.00302e-174 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

GGPPS_MOUSE
θ value	2.18449e-163 (rank : 2)	NC score	0.998581 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

DPS1_HUMAN
θ value	1.87187e-05 (rank : 3)	NC score	0.303145 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

FPPS_HUMAN
θ value	0.000270298 (rank : 4)	NC score	0.276589 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P14324	Gene names	FDPS, FPS, KIAA1293
Domain Architecture
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

DPS1_MOUSE
θ value	0.000602161 (rank : 5)	NC score	0.269631 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

FPPS_MOUSE
θ value	0.0961366 (rank : 6)	NC score	0.209664 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q920E5	Gene names	Fdps
Domain Architecture	No domain graphic available
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) (Cholesterol-regulated 39 kDa protein) (CR 39) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

TRIPB_HUMAN
θ value	8.99809 (rank : 7)	NC score	0.002968 (rank : 9)
Query Neighborhood Hits	7	Target Neighborhood Hits	1587	Shared Neighborhood Hits	2
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

DLP1_HUMAN
θ value	θ > 10 (rank : 8)	NC score	0.052224 (rank : 8)
Query Neighborhood Hits	7	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YH6, Q33DR4, Q4G158, Q5VU38, Q5VU39, Q9NR58	Gene names	PDSS2, C6orf210, DLP1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Candidate tumor suppressor protein).

DLP1_MOUSE
θ value	θ > 10 (rank : 9)	NC score	0.054321 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

Hits sorted by NC score

GGPPS_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.00302e-174 (rank : 1)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

GGPPS_MOUSE
NC score	0.998581 (rank : 2)	θ value	2.18449e-163 (rank : 2)
Query Neighborhood Hits	7	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

DPS1_HUMAN
NC score	0.303145 (rank : 3)	θ value	1.87187e-05 (rank : 3)
Query Neighborhood Hits	7	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

FPPS_HUMAN
NC score	0.276589 (rank : 4)	θ value	0.000270298 (rank : 4)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P14324	Gene names	FDPS, FPS, KIAA1293
Domain Architecture
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

DPS1_MOUSE
NC score	0.269631 (rank : 5)	θ value	0.000602161 (rank : 5)
Query Neighborhood Hits	7	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

FPPS_MOUSE
NC score	0.209664 (rank : 6)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	7	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q920E5	Gene names	Fdps
Domain Architecture	No domain graphic available
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) (Cholesterol-regulated 39 kDa protein) (CR 39) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

DLP1_MOUSE
NC score	0.054321 (rank : 7)	θ value	θ > 10 (rank : 9)
Query Neighborhood Hits	7	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

DLP1_HUMAN
NC score	0.052224 (rank : 8)	θ value	θ > 10 (rank : 8)
Query Neighborhood Hits	7	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YH6, Q33DR4, Q4G158, Q5VU38, Q5VU39, Q9NR58	Gene names	PDSS2, C6orf210, DLP1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Candidate tumor suppressor protein).

TRIPB_HUMAN
NC score	0.002968 (rank : 9)	θ value	8.99809 (rank : 7)
Query Neighborhood Hits	7	Target Neighborhood Hits	1587	Shared Neighborhood Hits	2
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).