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Network neighborhood for query Sequence : DLP1_HUMAN

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DLP1_HUMAN
SwissProt Accessions	Q86YH6, Q33DR4, Q4G158, Q5VU38, Q5VU39, Q9NR58	Gene names	PDSS2, C6orf210, DLP1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Candidate tumor suppressor protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DLP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YH6, Q33DR4, Q4G158, Q5VU38, Q5VU39, Q9NR58	Gene names	PDSS2, C6orf210, DLP1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Candidate tumor suppressor protein).

DLP1_MOUSE
θ value	0 (rank : 2)	NC score	0.996280 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

DPS1_MOUSE
θ value	3.88503e-19 (rank : 3)	NC score	0.634336 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

DPS1_HUMAN
θ value	2.60593e-15 (rank : 4)	NC score	0.606075 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

ELA2A_MOUSE
θ value	0.125558 (rank : 5)	NC score	0.014213 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ST32B_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.007997 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

STK6_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.005481 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

ST32B_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.007519 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	830	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

CP250_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.003431 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	1805	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

EMIL1_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.009055 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

HLF_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.011464 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

KKCC2_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.005048 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.005037 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	855	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

GGPPS_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.052224 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

Hits sorted by NC score

DLP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YH6, Q33DR4, Q4G158, Q5VU38, Q5VU39, Q9NR58	Gene names	PDSS2, C6orf210, DLP1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Candidate tumor suppressor protein).

DLP1_MOUSE
NC score	0.996280 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q33DR3, Q3USU6, Q9D3K7	Gene names	Pdss2, Dlp1
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 2) (Solanesyl-diphosphate synthase subunit 2).

DPS1_MOUSE
NC score	0.634336 (rank : 3)	θ value	3.88503e-19 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

DPS1_HUMAN
NC score	0.606075 (rank : 4)	θ value	2.60593e-15 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

GGPPS_HUMAN
NC score	0.052224 (rank : 5)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

ELA2A_MOUSE
NC score	0.014213 (rank : 6)	θ value	0.125558 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

HLF_MOUSE
NC score	0.011464 (rank : 7)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

EMIL1_HUMAN
NC score	0.009055 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

ST32B_MOUSE
NC score	0.007997 (rank : 9)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

ST32B_HUMAN
NC score	0.007519 (rank : 10)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	830	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

STK6_MOUSE
NC score	0.005481 (rank : 11)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

KKCC2_HUMAN
NC score	0.005048 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
NC score	0.005037 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	855	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

CP250_HUMAN
NC score	0.003431 (rank : 14)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	1805	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).