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Network neighborhood for query Sequence : FPPS_HUMAN

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FPPS_HUMAN
SwissProt Accessions	P14324	Gene names	FDPS, FPS, KIAA1293
Domain Architecture
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FPPS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P14324	Gene names	FDPS, FPS, KIAA1293
Domain Architecture
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

FPPS_MOUSE
θ value	1.11673e-175 (rank : 2)	NC score	0.995924 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q920E5	Gene names	Fdps
Domain Architecture	No domain graphic available
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) (Cholesterol-regulated 39 kDa protein) (CR 39) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

GGPPS_MOUSE
θ value	3.19293e-05 (rank : 3)	NC score	0.292997 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

GGPPS_HUMAN
θ value	0.000270298 (rank : 4)	NC score	0.276589 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

DPS1_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.134672 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

DPS1_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.116577 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

FA29A_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.044620 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z4H7, Q6IQ10, Q6NZX5, Q8IZQ4, Q96FN0, Q9H950, Q9H998, Q9HCJ8, Q9NXT8	Gene names	FAM29A, KIAA1574
Domain Architecture	No domain graphic available
Description	Protein FAM29A.

REM1_MOUSE
θ value	8.99809 (rank : 8)	NC score	0.004515 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

Hits sorted by NC score

FPPS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	P14324	Gene names	FDPS, FPS, KIAA1293
Domain Architecture
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

FPPS_MOUSE
NC score	0.995924 (rank : 2)	θ value	1.11673e-175 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q920E5	Gene names	Fdps
Domain Architecture	No domain graphic available
Description	Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) (Cholesterol-regulated 39 kDa protein) (CR 39) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)].

GGPPS_MOUSE
NC score	0.292997 (rank : 3)	θ value	3.19293e-05 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

GGPPS_HUMAN
NC score	0.276589 (rank : 4)	θ value	0.000270298 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O95749, Q5T2C8, Q6NW19	Gene names	GGPS1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

DPS1_HUMAN
NC score	0.134672 (rank : 5)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2R2, Q53F75, Q6P473, Q86WQ8, Q9Y2W5	Gene names	PDSS1, DPS1, TPRT
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Trans-prenyltransferase) (TPT).

DPS1_MOUSE
NC score	0.116577 (rank : 6)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q33DR2, Q9WU69	Gene names	Pdss1, Dps1, Sps1, Tprt
Domain Architecture	No domain graphic available
Description	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.-) (Decaprenyl pyrophosphate synthetase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase) (TPT).

FA29A_HUMAN
NC score	0.044620 (rank : 7)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z4H7, Q6IQ10, Q6NZX5, Q8IZQ4, Q96FN0, Q9H950, Q9H998, Q9HCJ8, Q9NXT8	Gene names	FAM29A, KIAA1574
Domain Architecture	No domain graphic available
Description	Protein FAM29A.

REM1_MOUSE
NC score	0.004515 (rank : 8)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).