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Network neighborhood for query Sequence : GGLO_MOUSE

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GGLO_MOUSE
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GGLO_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

D2HDH_HUMAN
θ value	2.52405e-10 (rank : 2)	NC score	0.478608 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N465, Q6IQ24, Q8N5Q8	Gene names	D2HGDH, D2HGD
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

DHC24_HUMAN
θ value	3.64472e-09 (rank : 3)	NC score	0.402291 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q15392, Q9HBA8	Gene names	DHCR24, KIAA0018
Domain Architecture
Description	24-dehydrocholesterol reductase precursor (EC 1.3.1.-) (3-beta- hydroxysterol delta-24-reductase) (Seladin-1) (Diminuto/dwarf1 homolog).

D2HDH_MOUSE
θ value	4.0297e-08 (rank : 4)	NC score	0.461467 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

ADAS_MOUSE
θ value	3.77169e-06 (rank : 5)	NC score	0.368661 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0I1	Gene names	Agps
Domain Architecture	No domain graphic available
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase).

ADAS_HUMAN
θ value	7.1131e-05 (rank : 6)	NC score	0.355848 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O00116, Q2TU35	Gene names	AGPS
Domain Architecture
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase) (Aging-associated protein 5).

TPH2_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.028300 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

EPHA1_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.001502 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	997	Shared Neighborhood Hits	2
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

TPH2_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.023005 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

Hits sorted by NC score

GGLO_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

D2HDH_HUMAN
NC score	0.478608 (rank : 2)	θ value	2.52405e-10 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N465, Q6IQ24, Q8N5Q8	Gene names	D2HGDH, D2HGD
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

D2HDH_MOUSE
NC score	0.461467 (rank : 3)	θ value	4.0297e-08 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

DHC24_HUMAN
NC score	0.402291 (rank : 4)	θ value	3.64472e-09 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q15392, Q9HBA8	Gene names	DHCR24, KIAA0018
Domain Architecture
Description	24-dehydrocholesterol reductase precursor (EC 1.3.1.-) (3-beta- hydroxysterol delta-24-reductase) (Seladin-1) (Diminuto/dwarf1 homolog).

ADAS_MOUSE
NC score	0.368661 (rank : 5)	θ value	3.77169e-06 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0I1	Gene names	Agps
Domain Architecture	No domain graphic available
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase).

ADAS_HUMAN
NC score	0.355848 (rank : 6)	θ value	7.1131e-05 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O00116, Q2TU35	Gene names	AGPS
Domain Architecture
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase) (Aging-associated protein 5).

TPH2_HUMAN
NC score	0.028300 (rank : 7)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_MOUSE
NC score	0.023005 (rank : 8)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

EPHA1_HUMAN
NC score	0.001502 (rank : 9)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	997	Shared Neighborhood Hits	2
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).