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Network neighborhood for query Sequence : D2HDH_MOUSE

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D2HDH_MOUSE
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

D2HDH_HUMAN
θ value	0 (rank : 1)	NC score	0.994663 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N465, Q6IQ24, Q8N5Q8	Gene names	D2HGDH, D2HGD
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

D2HDH_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

ADAS_HUMAN
θ value	3.76295e-14 (rank : 3)	NC score	0.515910 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O00116, Q2TU35	Gene names	AGPS
Domain Architecture
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase) (Aging-associated protein 5).

ADAS_MOUSE
θ value	1.42992e-13 (rank : 4)	NC score	0.512033 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0I1	Gene names	Agps
Domain Architecture	No domain graphic available
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase).

GGLO_MOUSE
θ value	4.0297e-08 (rank : 5)	NC score	0.461467 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

DHC24_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.108790 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q15392, Q9HBA8	Gene names	DHCR24, KIAA0018
Domain Architecture
Description	24-dehydrocholesterol reductase precursor (EC 1.3.1.-) (3-beta- hydroxysterol delta-24-reductase) (Seladin-1) (Diminuto/dwarf1 homolog).

MARK3_MOUSE
θ value	0.62314 (rank : 7)	NC score	0.009908 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	919	Shared Neighborhood Hits	4
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

MARK3_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.010253 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	893	Shared Neighborhood Hits	4
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

K0020_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.026838 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q15397, Q547G7, Q5SZY9, Q6IB47, Q96B27, Q96L78, Q96L79, Q96L80	Gene names	KIAA0020, XTP5
Domain Architecture	No domain graphic available
Description	Protein KIAA0020 (HBV X-transactivated gene 5 protein) (Minor histocompatibility antigen HA-8) (HLA-HA8).

PRG3_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.022868 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

NEDD4_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.012893 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.013163 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

EI2BD_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.017138 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

Hits sorted by NC score

D2HDH_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

D2HDH_HUMAN
NC score	0.994663 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N465, Q6IQ24, Q8N5Q8	Gene names	D2HGDH, D2HGD
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

ADAS_HUMAN
NC score	0.515910 (rank : 3)	θ value	3.76295e-14 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O00116, Q2TU35	Gene names	AGPS
Domain Architecture
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase) (Aging-associated protein 5).

ADAS_MOUSE
NC score	0.512033 (rank : 4)	θ value	1.42992e-13 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0I1	Gene names	Agps
Domain Architecture	No domain graphic available
Description	Alkyldihydroxyacetonephosphate synthase, peroxisomal precursor (EC 2.5.1.26) (Alkyl-DHAP synthase) (Alkylglycerone-phosphate synthase).

GGLO_MOUSE
NC score	0.461467 (rank : 5)	θ value	4.0297e-08 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P58710	Gene names	Gulo
Domain Architecture
Description	L-gulonolactone oxidase (EC 1.1.3.8) (LGO) (L-gulono-gamma-lactone oxidase) (GLO).

DHC24_HUMAN
NC score	0.108790 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q15392, Q9HBA8	Gene names	DHCR24, KIAA0018
Domain Architecture
Description	24-dehydrocholesterol reductase precursor (EC 1.3.1.-) (3-beta- hydroxysterol delta-24-reductase) (Seladin-1) (Diminuto/dwarf1 homolog).

K0020_HUMAN
NC score	0.026838 (rank : 7)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q15397, Q547G7, Q5SZY9, Q6IB47, Q96B27, Q96L78, Q96L79, Q96L80	Gene names	KIAA0020, XTP5
Domain Architecture	No domain graphic available
Description	Protein KIAA0020 (HBV X-transactivated gene 5 protein) (Minor histocompatibility antigen HA-8) (HLA-HA8).

PRG3_MOUSE
NC score	0.022868 (rank : 8)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

EI2BD_MOUSE
NC score	0.017138 (rank : 9)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

NEDD4_MOUSE
NC score	0.013163 (rank : 10)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
NC score	0.012893 (rank : 11)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

MARK3_HUMAN
NC score	0.010253 (rank : 12)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	893	Shared Neighborhood Hits	4
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

MARK3_MOUSE
NC score	0.009908 (rank : 13)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	919	Shared Neighborhood Hits	4
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).