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Network neighborhood for query Sequence : FACE1_HUMAN

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FACE1_HUMAN
SwissProt Accessions	O75844, Q8NDZ8, Q9UBQ2	Gene names	ZMPSTE24, FACE1, STE24
Domain Architecture
Description	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Zinc metalloproteinase Ste24 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FACE1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	O75844, Q8NDZ8, Q9UBQ2	Gene names	ZMPSTE24, FACE1, STE24
Domain Architecture
Description	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Zinc metalloproteinase Ste24 homolog).

FACE1_MOUSE
θ value	0 (rank : 2)	NC score	0.997361 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q80W54, Q8BJK4, Q8K569	Gene names	Zmpste24, Face1
Domain Architecture	No domain graphic available
Description	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Zinc metalloproteinase Ste24 homolog).

DSPP_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.020649 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	645	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FBX5_HUMAN
θ value	2.36792 (rank : 4)	NC score	0.040641 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

K2C1_HUMAN
θ value	6.88961 (rank : 5)	NC score	0.003306 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	624	Shared Neighborhood Hits	2
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

MRGA1_MOUSE
θ value	6.88961 (rank : 6)	NC score	0.006280 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WW5	Gene names	Mrgpra1, Mrga1
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member A1 (RF-amide G-protein coupled receptor).

S26A5_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.010332 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P58743, Q86UF8, Q86UF9, Q86UG0	Gene names	SLC26A5, PRES
Domain Architecture
Description	Prestin (Solute carrier family 26 member 5).

TGM3_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.013279 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q08188, O95933	Gene names	TGM3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

GR65_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.013096 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

Hits sorted by NC score

FACE1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	O75844, Q8NDZ8, Q9UBQ2	Gene names	ZMPSTE24, FACE1, STE24
Domain Architecture
Description	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Zinc metalloproteinase Ste24 homolog).

FACE1_MOUSE
NC score	0.997361 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q80W54, Q8BJK4, Q8K569	Gene names	Zmpste24, Face1
Domain Architecture	No domain graphic available
Description	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Zinc metalloproteinase Ste24 homolog).

FBX5_HUMAN
NC score	0.040641 (rank : 3)	θ value	2.36792 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

DSPP_HUMAN
NC score	0.020649 (rank : 4)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	645	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TGM3_HUMAN
NC score	0.013279 (rank : 5)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q08188, O95933	Gene names	TGM3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

GR65_HUMAN
NC score	0.013096 (rank : 6)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

S26A5_HUMAN
NC score	0.010332 (rank : 7)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P58743, Q86UF8, Q86UF9, Q86UG0	Gene names	SLC26A5, PRES
Domain Architecture
Description	Prestin (Solute carrier family 26 member 5).

MRGA1_MOUSE
NC score	0.006280 (rank : 8)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WW5	Gene names	Mrgpra1, Mrga1
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member A1 (RF-amide G-protein coupled receptor).

K2C1_HUMAN
NC score	0.003306 (rank : 9)	θ value	6.88961 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	624	Shared Neighborhood Hits	2
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).