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Network neighborhood for query Sequence : ELL2_HUMAN

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ELL2_HUMAN
SwissProt Accessions	O00472	Gene names	ELL2
Domain Architecture
Description	RNA polymerase II elongation factor ELL2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ELL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	O00472	Gene names	ELL2
Domain Architecture
Description	RNA polymerase II elongation factor ELL2.

ELL_HUMAN
θ value	2.54029e-103 (rank : 2)	NC score	0.909385 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ELL_MOUSE
θ value	2.15048e-102 (rank : 3)	NC score	0.924470 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ELL3_HUMAN
θ value	3.74554e-30 (rank : 4)	NC score	0.790504 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB65, Q9H634	Gene names	ELL3
Domain Architecture
Description	RNA polymerase II elongation factor ELL3.

ELL3_MOUSE
θ value	8.3442e-30 (rank : 5)	NC score	0.783232 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VR2	Gene names	Ell3
Domain Architecture
Description	RNA polymerase II elongation factor ELL3.

OCLN_HUMAN
θ value	4.59992e-12 (rank : 6)	NC score	0.543033 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

OCLN_MOUSE
θ value	4.59992e-12 (rank : 7)	NC score	0.542223 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q61146, Q544A7	Gene names	Ocln, Ocl
Domain Architecture
Description	Occludin.

CCD46_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.041428 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	1430	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

UBP48_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.032797 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

CUTL1_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.037642 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	1574	Shared Neighborhood Hits	40
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

ANK2_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.019889 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	1615	Shared Neighborhood Hits	28
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BAZ2A_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.031990 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	744	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BICD2_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.043856 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	856	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.043059 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	864	Shared Neighborhood Hits	29
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

NAF1_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.050493 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	852	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NAF1_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.050066 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	937	Shared Neighborhood Hits	36
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

PAG1_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.045871 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWQ8, Q2M1Z9, Q5BKU4, Q9NYK0	Gene names	PAG1, CBP, PAG
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Transmembrane adapter protein PAG) (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

SMC2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.039861 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	1405	Shared Neighborhood Hits	37
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SDCG1_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.040078 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

CCD21_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.040710 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD46_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.036558 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

LAMA3_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.022328 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	760	Shared Neighborhood Hits	22
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

UBIP1_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.021732 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

PIBF1_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.042229 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	1041	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

SMC1A_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.041932 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	1346	Shared Neighborhood Hits	38
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.041124 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	1384	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TXND2_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.022737 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	793	Shared Neighborhood Hits	15
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ZN287_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.000151 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	777	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.

ANKY2_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.020258 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASPP2_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.028500 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	1156	Shared Neighborhood Hits	36
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CCD21_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.036132 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	1228	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CK5P2_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.032832 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	39
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

IWS1_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.025837 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RGS3_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.020686 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	1621	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RRP5_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.038819 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	12
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SC24A_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.033894 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SYCP1_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.034744 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	1456	Shared Neighborhood Hits	41
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EP400_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.018106 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	592	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

LCP2_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.024889 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MUCDL_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.023866 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	777	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ZBT25_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.011315 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	644	Shared Neighborhood Hits	3
SwissProt Accessions	P24278, Q8IYH9	Gene names	ZBTB25, KUP, ZNF46
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP).

ADAM8_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.006642 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

AL2S4_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.026023 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

CA065_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.046357 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	469	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

MAGE1_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.014727 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	1389	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ABCB7_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.008177 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

AFF4_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.018595 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	581	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CENPF_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.027198 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	1932	Shared Neighborhood Hits	41
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP57_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.058502 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	580	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

FAK2_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.000576 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	847	Shared Neighborhood Hits	6
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

GGA1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.012700 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

INVO_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.036239 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

LR37B_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.013759 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

PCLO_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.025423 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RSF1_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.031260 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	539	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SON_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.013578 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	1568	Shared Neighborhood Hits	23
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

2ACA_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.018268 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

CLIC5_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.009234 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZA1, Q5T4Z0, Q96JT5, Q9BWZ0	Gene names	CLIC5
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel protein 5.

GA2L2_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.012591 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

LPP_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.007898 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	775	Shared Neighborhood Hits	11
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SAS6_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.030111 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	931	Shared Neighborhood Hits	31
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

ABTB2_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.009039 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CCD50_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.026666 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	237	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD50_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.024838 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CDC27_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.010800 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CENPU_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.027182 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CEP57_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.053485 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	576	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CP007_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.014847 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CT2NL_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.024300 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	1059	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HPS4_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.014091 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

MRCKG_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.006609 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	1519	Shared Neighborhood Hits	29
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PCIF1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.012336 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

RABE1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.024960 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	1104	Shared Neighborhood Hits	32
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ROCK2_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.010809 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	2072	Shared Neighborhood Hits	35
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RUFY2_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.022563 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	1208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

XL3A_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.016499 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

ZN518_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.003018 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	780	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.

Hits sorted by NC score

ELL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	O00472	Gene names	ELL2
Domain Architecture
Description	RNA polymerase II elongation factor ELL2.

ELL_MOUSE
NC score	0.924470 (rank : 2)	θ value	2.15048e-102 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ELL_HUMAN
NC score	0.909385 (rank : 3)	θ value	2.54029e-103 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ELL3_HUMAN
NC score	0.790504 (rank : 4)	θ value	3.74554e-30 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB65, Q9H634	Gene names	ELL3
Domain Architecture
Description	RNA polymerase II elongation factor ELL3.

ELL3_MOUSE
NC score	0.783232 (rank : 5)	θ value	8.3442e-30 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VR2	Gene names	Ell3
Domain Architecture
Description	RNA polymerase II elongation factor ELL3.

OCLN_HUMAN
NC score	0.543033 (rank : 6)	θ value	4.59992e-12 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

OCLN_MOUSE
NC score	0.542223 (rank : 7)	θ value	4.59992e-12 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q61146, Q544A7	Gene names	Ocln, Ocl
Domain Architecture
Description	Occludin.

CEP57_MOUSE
NC score	0.058502 (rank : 8)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	580	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP57_HUMAN
NC score	0.053485 (rank : 9)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	576	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

NAF1_MOUSE
NC score	0.050493 (rank : 10)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	852	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NAF1_HUMAN
NC score	0.050066 (rank : 11)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	937	Shared Neighborhood Hits	36
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

CA065_HUMAN
NC score	0.046357 (rank : 12)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	469	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

PAG1_HUMAN
NC score	0.045871 (rank : 13)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWQ8, Q2M1Z9, Q5BKU4, Q9NYK0	Gene names	PAG1, CBP, PAG
Domain Architecture	No domain graphic available
Description	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Transmembrane adapter protein PAG) (Csk-binding protein) (Transmembrane phosphoprotein Cbp).

BICD2_HUMAN
NC score	0.043856 (rank : 14)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	856	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
NC score	0.043059 (rank : 15)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	864	Shared Neighborhood Hits	29
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

PIBF1_HUMAN
NC score	0.042229 (rank : 16)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	1041	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

SMC1A_HUMAN
NC score	0.041932 (rank : 17)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	1346	Shared Neighborhood Hits	38
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

CCD46_HUMAN
NC score	0.041428 (rank : 18)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	1430	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SMC1A_MOUSE
NC score	0.041124 (rank : 19)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	1384	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CCD21_MOUSE
NC score	0.040710 (rank : 20)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SDCG1_MOUSE
NC score	0.040078 (rank : 21)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

SMC2_HUMAN
NC score	0.039861 (rank : 22)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	1405	Shared Neighborhood Hits	37
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

RRP5_HUMAN
NC score	0.038819 (rank : 23)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	12
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

CUTL1_HUMAN
NC score	0.037642 (rank : 24)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	1574	Shared Neighborhood Hits	40
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CCD46_MOUSE
NC score	0.036558 (rank : 25)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

INVO_HUMAN
NC score	0.036239 (rank : 26)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CCD21_HUMAN
NC score	0.036132 (rank : 27)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	1228	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SYCP1_MOUSE
NC score	0.034744 (rank : 28)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	1456	Shared Neighborhood Hits	41
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SC24A_MOUSE
NC score	0.033894 (rank : 29)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

CK5P2_HUMAN
NC score	0.032832 (rank : 30)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	1433	Shared Neighborhood Hits	39
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

UBP48_HUMAN
NC score	0.032797 (rank : 31)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

BAZ2A_MOUSE
NC score	0.031990 (rank : 32)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	744	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

RSF1_HUMAN
NC score	0.031260 (rank : 33)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	539	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SAS6_MOUSE
NC score	0.030111 (rank : 34)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	931	Shared Neighborhood Hits	31
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

ASPP2_HUMAN
NC score	0.028500 (rank : 35)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	1156	Shared Neighborhood Hits	36
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CENPF_HUMAN
NC score	0.027198 (rank : 36)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	1932	Shared Neighborhood Hits	41
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CENPU_HUMAN
NC score	0.027182 (rank : 37)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CCD50_HUMAN
NC score	0.026666 (rank : 38)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	237	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

AL2S4_MOUSE
NC score	0.026023 (rank : 39)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

IWS1_MOUSE
NC score	0.025837 (rank : 40)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCLO_HUMAN
NC score	0.025423 (rank : 41)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RABE1_HUMAN
NC score	0.024960 (rank : 42)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	1104	Shared Neighborhood Hits	32
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

LCP2_HUMAN
NC score	0.024889 (rank : 43)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CCD50_MOUSE
NC score	0.024838 (rank : 44)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CT2NL_HUMAN
NC score	0.024300 (rank : 45)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	1059	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MUCDL_HUMAN
NC score	0.023866 (rank : 46)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	777	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TXND2_HUMAN
NC score	0.022737 (rank : 47)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	793	Shared Neighborhood Hits	15
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RUFY2_HUMAN
NC score	0.022563 (rank : 48)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	1208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

LAMA3_HUMAN
NC score	0.022328 (rank : 49)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	760	Shared Neighborhood Hits	22
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

UBIP1_HUMAN
NC score	0.021732 (rank : 50)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

RGS3_MOUSE
NC score	0.020686 (rank : 51)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	1621	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ANKY2_MOUSE
NC score	0.020258 (rank : 52)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANK2_HUMAN
NC score	0.019889 (rank : 53)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	1615	Shared Neighborhood Hits	28
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

AFF4_MOUSE
NC score	0.018595 (rank : 54)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	581	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

2ACA_HUMAN
NC score	0.018268 (rank : 55)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

EP400_MOUSE
NC score	0.018106 (rank : 56)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	592	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

XL3A_MOUSE
NC score	0.016499 (rank : 57)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

CP007_MOUSE
NC score	0.014847 (rank : 58)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

MAGE1_HUMAN
NC score	0.014727 (rank : 59)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	1389	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

HPS4_MOUSE
NC score	0.014091 (rank : 60)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

LR37B_HUMAN
NC score	0.013759 (rank : 61)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

SON_HUMAN
NC score	0.013578 (rank : 62)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	1568	Shared Neighborhood Hits	23
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GGA1_HUMAN
NC score	0.012700 (rank : 63)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GA2L2_MOUSE
NC score	0.012591 (rank : 64)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PCIF1_HUMAN
NC score	0.012336 (rank : 65)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

ZBT25_HUMAN
NC score	0.011315 (rank : 66)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	644	Shared Neighborhood Hits	3
SwissProt Accessions	P24278, Q8IYH9	Gene names	ZBTB25, KUP, ZNF46
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP).

ROCK2_MOUSE
NC score	0.010809 (rank : 67)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	2072	Shared Neighborhood Hits	35
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CDC27_HUMAN
NC score	0.010800 (rank : 68)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CLIC5_HUMAN
NC score	0.009234 (rank : 69)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZA1, Q5T4Z0, Q96JT5, Q9BWZ0	Gene names	CLIC5
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel protein 5.

ABTB2_HUMAN
NC score	0.009039 (rank : 70)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABCB7_HUMAN
NC score	0.008177 (rank : 71)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

LPP_HUMAN
NC score	0.007898 (rank : 72)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	775	Shared Neighborhood Hits	11
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ADAM8_HUMAN
NC score	0.006642 (rank : 73)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

MRCKG_HUMAN
NC score	0.006609 (rank : 74)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	1519	Shared Neighborhood Hits	29
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

ZN518_HUMAN
NC score	0.003018 (rank : 75)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	780	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.

FAK2_HUMAN
NC score	0.000576 (rank : 76)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	847	Shared Neighborhood Hits	6
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ZN287_HUMAN
NC score	0.000151 (rank : 77)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	777	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.