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Network neighborhood for query Sequence : EDAD_HUMAN

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EDAD_HUMAN
SwissProt Accessions	Q8WWZ3, Q5VYJ7	Gene names	EDARADD
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EDAD_HUMAN
θ value	7.84197e-129 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWZ3, Q5VYJ7	Gene names	EDARADD
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled homolog).

EDAD_MOUSE
θ value	1.54472e-92 (rank : 2)	NC score	0.987089 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHX2	Gene names	Edaradd, Cr
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled protein).

MYD88_MOUSE
θ value	0.00228821 (rank : 3)	NC score	0.172697 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P22366, O35916	Gene names	Myd88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

TRHDE_MOUSE
θ value	0.163984 (rank : 4)	NC score	0.058301 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K093	Gene names	Trhde
Domain Architecture	No domain graphic available
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TRHDE_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.056175 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TEFF2_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.042460 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.042404 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

BFAR_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.035380 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

GP155_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.038272 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

MYD88_HUMAN
θ value	θ > 10 (rank : 10)	NC score	0.060835 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	47	Shared Neighborhood Hits	1
SwissProt Accessions	Q99836, P78397	Gene names	MYD88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

Hits sorted by NC score

EDAD_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.84197e-129 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWZ3, Q5VYJ7	Gene names	EDARADD
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled homolog).

EDAD_MOUSE
NC score	0.987089 (rank : 2)	θ value	1.54472e-92 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHX2	Gene names	Edaradd, Cr
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled protein).

MYD88_MOUSE
NC score	0.172697 (rank : 3)	θ value	0.00228821 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P22366, O35916	Gene names	Myd88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

MYD88_HUMAN
NC score	0.060835 (rank : 4)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	47	Shared Neighborhood Hits	1
SwissProt Accessions	Q99836, P78397	Gene names	MYD88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

TRHDE_MOUSE
NC score	0.058301 (rank : 5)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K093	Gene names	Trhde
Domain Architecture	No domain graphic available
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TRHDE_HUMAN
NC score	0.056175 (rank : 6)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TEFF2_HUMAN
NC score	0.042460 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	211	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.042404 (rank : 8)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

GP155_HUMAN
NC score	0.038272 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

BFAR_HUMAN
NC score	0.035380 (rank : 10)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).