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Network neighborhood for query Sequence : CU069_HUMAN

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CU069_HUMAN
SwissProt Accessions	P58556	Gene names	C21orf69
Domain Architecture	No domain graphic available
Description	Protein C21orf69.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CU069_HUMAN
θ value	1.76329e-96 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P58556	Gene names	C21orf69
Domain Architecture	No domain graphic available
Description	Protein C21orf69.

ALEX_HUMAN
θ value	3.0926 (rank : 2)	NC score	0.044779 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GBX1_MOUSE
θ value	3.0926 (rank : 3)	NC score	0.015136 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

PSL1_HUMAN
θ value	5.27518 (rank : 4)	NC score	0.025322 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

HES7_HUMAN
θ value	6.88961 (rank : 5)	NC score	0.029885 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

PTPRS_HUMAN
θ value	6.88961 (rank : 6)	NC score	0.007196 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

ASM_HUMAN
θ value	8.99809 (rank : 7)	NC score	0.021679 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P17405, P17406, Q13811, Q16837, Q16841	Gene names	SMPD1, ASM
Domain Architecture
Description	Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase).

ERF_MOUSE
θ value	8.99809 (rank : 8)	NC score	0.013206 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

IRS2_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.019502 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MK07_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.003221 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1087	Shared Neighborhood Hits	3
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

Hits sorted by NC score

CU069_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.76329e-96 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P58556	Gene names	C21orf69
Domain Architecture	No domain graphic available
Description	Protein C21orf69.

ALEX_HUMAN
NC score	0.044779 (rank : 2)	θ value	3.0926 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

HES7_HUMAN
NC score	0.029885 (rank : 3)	θ value	6.88961 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

PSL1_HUMAN
NC score	0.025322 (rank : 4)	θ value	5.27518 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ASM_HUMAN
NC score	0.021679 (rank : 5)	θ value	8.99809 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P17405, P17406, Q13811, Q16837, Q16841	Gene names	SMPD1, ASM
Domain Architecture
Description	Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase).

IRS2_MOUSE
NC score	0.019502 (rank : 6)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

GBX1_MOUSE
NC score	0.015136 (rank : 7)	θ value	3.0926 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

ERF_MOUSE
NC score	0.013206 (rank : 8)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

PTPRS_HUMAN
NC score	0.007196 (rank : 9)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

MK07_HUMAN
NC score	0.003221 (rank : 10)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1087	Shared Neighborhood Hits	3
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).