Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CRADD_MOUSE

For an explanation of this page, click here

CRADD_MOUSE
SwissProt Accessions	O88843, Q9QUN0	Gene names	Cradd, Raidd
Domain Architecture
Description	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CRADD_MOUSE
θ value	1.54114e-100 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O88843, Q9QUN0	Gene names	Cradd, Raidd
Domain Architecture
Description	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain).

CRADD_HUMAN
θ value	2.72669e-89 (rank : 2)	NC score	0.989122 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P78560	Gene names	CRADD, RAIDD
Domain Architecture
Description	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain).

CASP2_MOUSE
θ value	0.00298849 (rank : 3)	NC score	0.156210 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASP2_HUMAN
θ value	0.00665767 (rank : 4)	NC score	0.153708 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9	Gene names	CASP2, ICH1
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

ANK2_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.035254 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	1615	Shared Neighborhood Hits	7
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.030371 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	853	Shared Neighborhood Hits	6
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

PIDD_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.049647 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	256	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

PIDD_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.044459 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

ASC_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.038118 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BCL10_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.074390 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O95999	Gene names	BCL10, CIPER, CLAP
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (hCLAP).

FADD_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.080247 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

BCL10_MOUSE
θ value	θ > 10 (rank : 12)	NC score	0.051917 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H7, Q3UBN4	Gene names	Bcl10, Ciper, Clap
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (mCLAP).

Hits sorted by NC score

CRADD_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.54114e-100 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O88843, Q9QUN0	Gene names	Cradd, Raidd
Domain Architecture
Description	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain).

CRADD_HUMAN
NC score	0.989122 (rank : 2)	θ value	2.72669e-89 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P78560	Gene names	CRADD, RAIDD
Domain Architecture
Description	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain).

CASP2_MOUSE
NC score	0.156210 (rank : 3)	θ value	0.00298849 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASP2_HUMAN
NC score	0.153708 (rank : 4)	θ value	0.00665767 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9	Gene names	CASP2, ICH1
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

FADD_HUMAN
NC score	0.080247 (rank : 5)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

BCL10_HUMAN
NC score	0.074390 (rank : 6)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O95999	Gene names	BCL10, CIPER, CLAP
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (hCLAP).

BCL10_MOUSE
NC score	0.051917 (rank : 7)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0H7, Q3UBN4	Gene names	Bcl10, Ciper, Clap
Domain Architecture
Description	B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein) (mCLAP).

PIDD_MOUSE
NC score	0.049647 (rank : 8)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	256	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

PIDD_HUMAN
NC score	0.044459 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

ASC_MOUSE
NC score	0.038118 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ANK2_HUMAN
NC score	0.035254 (rank : 11)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	1615	Shared Neighborhood Hits	7
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
NC score	0.030371 (rank : 12)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	853	Shared Neighborhood Hits	6
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).