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Network neighborhood for query Sequence : CLCN1_MOUSE

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CLCN1_MOUSE
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CLCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.994108 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	29
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.987254 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P51788, O14864, Q8WU13	Gene names	CLCN2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.987564 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCKA_MOUSE
θ value	6.63862e-128 (rank : 5)	NC score	0.961285 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB7, Q6UB69, Q8JZU7	Gene names	Clcnka, Clcnk1
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKA_HUMAN
θ value	1.93155e-127 (rank : 6)	NC score	0.955586 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51800, Q7Z6D1, Q86VT1	Gene names	CLCNKA
Domain Architecture
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKB_HUMAN
θ value	8.11517e-126 (rank : 7)	NC score	0.958773 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51801	Gene names	CLCNKB
Domain Architecture
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKB_MOUSE
θ value	2.06847e-121 (rank : 8)	NC score	0.956515 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB6, Q8VCF8	Gene names	Clcnkb, Clckb, Clcnk1l
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCN5_HUMAN
θ value	9.48078e-50 (rank : 9)	NC score	0.833875 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P51795, Q5JQD5	Gene names	CLCN5, CLCK2
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN5_MOUSE
θ value	3.60269e-49 (rank : 10)	NC score	0.836479 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVD4	Gene names	Clcn5, Clc5
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN3_HUMAN
θ value	3.37202e-47 (rank : 11)	NC score	0.822329 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51790, O14918, Q86Z21	Gene names	CLCN3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN4_HUMAN
θ value	4.40402e-47 (rank : 12)	NC score	0.828124 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51793, Q9UBU1	Gene names	CLCN4
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN3_MOUSE
θ value	1.28137e-46 (rank : 13)	NC score	0.823082 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51791	Gene names	Clcn3, Clc3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN4_MOUSE
θ value	2.41655e-45 (rank : 14)	NC score	0.823644 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q61418	Gene names	Clcn4, Clc4, Clcn4-2
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN7_HUMAN
θ value	2.86122e-38 (rank : 15)	NC score	0.827165 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P51798, Q9NYX5	Gene names	CLCN7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN7_MOUSE
θ value	6.37413e-38 (rank : 16)	NC score	0.826533 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN6_HUMAN
θ value	7.54701e-31 (rank : 17)	NC score	0.781052 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

CLCN6_MOUSE
θ value	8.3442e-30 (rank : 18)	NC score	0.774861 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

IF4G1_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.020594 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	534	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

FRS3_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.023608 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

TXND2_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.013362 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	793	Shared Neighborhood Hits	9
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RGS3_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.014624 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	1621	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

LTB1L_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.015549 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.015582 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

RPGF1_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.015806 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

NEK11_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.003135 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	1043	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

MILK2_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.011785 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

TERT_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.019122 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O70372, O35432, Q9JK99	Gene names	Tert
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit).

LTB1L_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.013422 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.013408 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	479	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MAP1B_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.010739 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	977	Shared Neighborhood Hits	16
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CIC_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.012406 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	992	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.014939 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAST4_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.000153 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	1804	Shared Neighborhood Hits	20
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RPTN_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.005072 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TJAP1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.012178 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MNT_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.015912 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	432	Shared Neighborhood Hits	14
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

WNK1_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.001500 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CEND1_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.013888 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

OBSCN_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.000071 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	1931	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RGS3_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.008571 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	1375	Shared Neighborhood Hits	19
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SO2A1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.014928 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

WNK3_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.001124 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

CD2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.008816 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CEND1_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.014286 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

PCLO_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.005952 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RTN4_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.009912 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	341	Shared Neighborhood Hits	14
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SMPX_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.017721 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DC77, Q4QRM9, Q8CEX8, Q9ER98	Gene names	Smpx, Csl
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein) (Chisel protein).

SNIP_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.009448 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

HCLS1_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.005468 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HSPB8_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.007770 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

K1949_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.009502 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

MAGE1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.003702 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	1389	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MNT_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.012837 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	496	Shared Neighborhood Hits	15
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PSL1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.006900 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SPEG_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.003096 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	1762	Shared Neighborhood Hits	22
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZF276_HUMAN
θ value	6.88961 (rank : 57)	NC score	-0.002104 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	768	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).

CD47_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.008843 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q08722, Q53Y71, Q96A60	Gene names	CD47
Domain Architecture
Description	Leukocyte surface antigen CD47 precursor (Integrin-associated protein) (IAP) (Antigenic surface determinant protein OA3) (Protein MER6).

CML2_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.000114 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

DOK2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.007334 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	244	Shared Neighborhood Hits	6
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

MINT_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.004650 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	1514	Shared Neighborhood Hits	22
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

Hits sorted by NC score

CLCN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN1_HUMAN
NC score	0.994108 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	29
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN2_MOUSE
NC score	0.987564 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCN2_HUMAN
NC score	0.987254 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P51788, O14864, Q8WU13	Gene names	CLCN2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCKA_MOUSE
NC score	0.961285 (rank : 5)	θ value	6.63862e-128 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB7, Q6UB69, Q8JZU7	Gene names	Clcnka, Clcnk1
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKB_HUMAN
NC score	0.958773 (rank : 6)	θ value	8.11517e-126 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51801	Gene names	CLCNKB
Domain Architecture
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKB_MOUSE
NC score	0.956515 (rank : 7)	θ value	2.06847e-121 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB6, Q8VCF8	Gene names	Clcnkb, Clckb, Clcnk1l
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKA_HUMAN
NC score	0.955586 (rank : 8)	θ value	1.93155e-127 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51800, Q7Z6D1, Q86VT1	Gene names	CLCNKA
Domain Architecture
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCN5_MOUSE
NC score	0.836479 (rank : 9)	θ value	3.60269e-49 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVD4	Gene names	Clcn5, Clc5
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN5_HUMAN
NC score	0.833875 (rank : 10)	θ value	9.48078e-50 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P51795, Q5JQD5	Gene names	CLCN5, CLCK2
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN4_HUMAN
NC score	0.828124 (rank : 11)	θ value	4.40402e-47 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51793, Q9UBU1	Gene names	CLCN4
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN7_HUMAN
NC score	0.827165 (rank : 12)	θ value	2.86122e-38 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P51798, Q9NYX5	Gene names	CLCN7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN7_MOUSE
NC score	0.826533 (rank : 13)	θ value	6.37413e-38 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN4_MOUSE
NC score	0.823644 (rank : 14)	θ value	2.41655e-45 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q61418	Gene names	Clcn4, Clc4, Clcn4-2
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN3_MOUSE
NC score	0.823082 (rank : 15)	θ value	1.28137e-46 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51791	Gene names	Clcn3, Clc3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN3_HUMAN
NC score	0.822329 (rank : 16)	θ value	3.37202e-47 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51790, O14918, Q86Z21	Gene names	CLCN3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN6_HUMAN
NC score	0.781052 (rank : 17)	θ value	7.54701e-31 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

CLCN6_MOUSE
NC score	0.774861 (rank : 18)	θ value	8.3442e-30 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

FRS3_HUMAN
NC score	0.023608 (rank : 19)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

IF4G1_MOUSE
NC score	0.020594 (rank : 20)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	534	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

TERT_MOUSE
NC score	0.019122 (rank : 21)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O70372, O35432, Q9JK99	Gene names	Tert
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit).

SMPX_MOUSE
NC score	0.017721 (rank : 22)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DC77, Q4QRM9, Q8CEX8, Q9ER98	Gene names	Smpx, Csl
Domain Architecture	No domain graphic available
Description	Small muscular protein (Stretch-responsive skeletal muscle protein) (Chisel protein).

MNT_MOUSE
NC score	0.015912 (rank : 23)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	432	Shared Neighborhood Hits	14
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RPGF1_HUMAN
NC score	0.015806 (rank : 24)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

LTB1S_HUMAN
NC score	0.015582 (rank : 25)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.015549 (rank : 26)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CIC_MOUSE
NC score	0.014939 (rank : 27)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SO2A1_MOUSE
NC score	0.014928 (rank : 28)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

RGS3_MOUSE
NC score	0.014624 (rank : 29)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	1621	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CEND1_MOUSE
NC score	0.014286 (rank : 30)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.013888 (rank : 31)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

LTB1L_MOUSE
NC score	0.013422 (rank : 32)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.013408 (rank : 33)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	479	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TXND2_HUMAN
NC score	0.013362 (rank : 34)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	793	Shared Neighborhood Hits	9
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MNT_HUMAN
NC score	0.012837 (rank : 35)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	496	Shared Neighborhood Hits	15
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

CIC_HUMAN
NC score	0.012406 (rank : 36)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	992	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TJAP1_MOUSE
NC score	0.012178 (rank : 37)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MILK2_HUMAN
NC score	0.011785 (rank : 38)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MAP1B_MOUSE
NC score	0.010739 (rank : 39)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	977	Shared Neighborhood Hits	16
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RTN4_MOUSE
NC score	0.009912 (rank : 40)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	341	Shared Neighborhood Hits	14
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

K1949_HUMAN
NC score	0.009502 (rank : 41)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

SNIP_HUMAN
NC score	0.009448 (rank : 42)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

CD47_HUMAN
NC score	0.008843 (rank : 43)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q08722, Q53Y71, Q96A60	Gene names	CD47
Domain Architecture
Description	Leukocyte surface antigen CD47 precursor (Integrin-associated protein) (IAP) (Antigenic surface determinant protein OA3) (Protein MER6).

CD2_HUMAN
NC score	0.008816 (rank : 44)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

RGS3_HUMAN
NC score	0.008571 (rank : 45)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	1375	Shared Neighborhood Hits	19
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

HSPB8_HUMAN
NC score	0.007770 (rank : 46)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJY1, Q6FIH3, Q9UKS3	Gene names	HSPB8, CRYAC, E2IG1, HSP22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22) (E2-induced gene 1 protein) (Protein kinase H11).

DOK2_MOUSE
NC score	0.007334 (rank : 47)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	244	Shared Neighborhood Hits	6
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

PSL1_HUMAN
NC score	0.006900 (rank : 48)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PCLO_HUMAN
NC score	0.005952 (rank : 49)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HCLS1_MOUSE
NC score	0.005468 (rank : 50)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

RPTN_MOUSE
NC score	0.005072 (rank : 51)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

MINT_MOUSE
NC score	0.004650 (rank : 52)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	1514	Shared Neighborhood Hits	22
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MAGE1_HUMAN
NC score	0.003702 (rank : 53)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	1389	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NEK11_HUMAN
NC score	0.003135 (rank : 54)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	1043	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

SPEG_HUMAN
NC score	0.003096 (rank : 55)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	1762	Shared Neighborhood Hits	22
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WNK1_HUMAN
NC score	0.001500 (rank : 56)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK3_HUMAN
NC score	0.001124 (rank : 57)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	948	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

MAST4_HUMAN
NC score	0.000153 (rank : 58)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	1804	Shared Neighborhood Hits	20
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CML2_HUMAN
NC score	0.000114 (rank : 59)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

OBSCN_HUMAN
NC score	0.000071 (rank : 60)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	1931	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ZF276_HUMAN
NC score	-0.002104 (rank : 61)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	768	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).