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Network neighborhood for query Sequence : CHKB_MOUSE

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CHKB_MOUSE
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHKB_HUMAN
θ value	0 (rank : 1)	NC score	0.998955 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y259, Q13388	Gene names	CHKB, CHETK, CHKL
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKB_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKA_MOUSE
θ value	4.7686e-118 (rank : 3)	NC score	0.983151 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKA_HUMAN
θ value	2.89301e-115 (rank : 4)	NC score	0.981566 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P35790, Q8NE29	Gene names	CHKA, CHK, CKI
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

EKI1_HUMAN
θ value	3.37985e-39 (rank : 5)	NC score	0.857952 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBU6	Gene names	ETNK1, EKI1
Domain Architecture
Description	Ethanolamine kinase 1 (EC 2.7.1.82) (EKI 1).

EKI2_HUMAN
θ value	2.35151e-24 (rank : 6)	NC score	0.780153 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVF9	Gene names	ETNK2, EKI2
Domain Architecture
Description	Ethanolamine kinase 2 (EC 2.7.1.82) (EKI 2) (Ethanolamine kinase-like protein).

RENT2_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.025308 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	618	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

DPP4_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.012592 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

NCOA2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.007532 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	281	Shared Neighborhood Hits	2
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ABCA5_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.003613 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ACET_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.011072 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.010920 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

Hits sorted by NC score

CHKB_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKB_HUMAN
NC score	0.998955 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y259, Q13388	Gene names	CHKB, CHETK, CHKL
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

CHKA_MOUSE
NC score	0.983151 (rank : 3)	θ value	4.7686e-118 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CHKA_HUMAN
NC score	0.981566 (rank : 4)	θ value	2.89301e-115 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P35790, Q8NE29	Gene names	CHKA, CHK, CKI
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

EKI1_HUMAN
NC score	0.857952 (rank : 5)	θ value	3.37985e-39 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBU6	Gene names	ETNK1, EKI1
Domain Architecture
Description	Ethanolamine kinase 1 (EC 2.7.1.82) (EKI 1).

EKI2_HUMAN
NC score	0.780153 (rank : 6)	θ value	2.35151e-24 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVF9	Gene names	ETNK2, EKI2
Domain Architecture
Description	Ethanolamine kinase 2 (EC 2.7.1.82) (EKI 2) (Ethanolamine kinase-like protein).

RENT2_HUMAN
NC score	0.025308 (rank : 7)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	618	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

DPP4_MOUSE
NC score	0.012592 (rank : 8)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

ACET_HUMAN
NC score	0.011072 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
NC score	0.010920 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

NCOA2_HUMAN
NC score	0.007532 (rank : 11)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	281	Shared Neighborhood Hits	2
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ABCA5_HUMAN
NC score	0.003613 (rank : 12)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.