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Network neighborhood for query Sequence : ACET_HUMAN

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ACET_HUMAN
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACET_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACET_MOUSE
θ value	0 (rank : 2)	NC score	0.998453 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
θ value	0 (rank : 3)	NC score	0.995967 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ACE_MOUSE
θ value	0 (rank : 4)	NC score	0.993175 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

ACE2_MOUSE
θ value	8.0589e-150 (rank : 5)	NC score	0.933768 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

ACE2_HUMAN
θ value	9.22056e-146 (rank : 6)	NC score	0.929954 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

CHIT1_MOUSE
θ value	0.125558 (rank : 7)	NC score	0.048730 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

MY18A_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.006803 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	1929	Shared Neighborhood Hits	5
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.007626 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	1989	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CENPJ_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.021643 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	721	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

TDRD6_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.019938 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

CHKB_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.011072 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

UBP34_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.009925 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.009982 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

TMM27_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.220555 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBJ8, Q6UW07	Gene names	TMEM27
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

TMM27_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.246780 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESG4, Q3UFF6	Gene names	Tmem27, Nx17
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

Hits sorted by NC score

ACET_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACET_MOUSE
NC score	0.998453 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
NC score	0.995967 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ACE_MOUSE
NC score	0.993175 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

ACE2_MOUSE
NC score	0.933768 (rank : 5)	θ value	8.0589e-150 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

ACE2_HUMAN
NC score	0.929954 (rank : 6)	θ value	9.22056e-146 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

TMM27_MOUSE
NC score	0.246780 (rank : 7)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESG4, Q3UFF6	Gene names	Tmem27, Nx17
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

TMM27_HUMAN
NC score	0.220555 (rank : 8)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBJ8, Q6UW07	Gene names	TMEM27
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

CHIT1_MOUSE
NC score	0.048730 (rank : 9)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

CENPJ_HUMAN
NC score	0.021643 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	721	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

TDRD6_MOUSE
NC score	0.019938 (rank : 11)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

CHKB_MOUSE
NC score	0.011072 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O55229	Gene names	Chkb, Chetk, Chkl
Domain Architecture
Description	Choline/ethanolamine kinase [Includes: Choline kinase beta (EC 2.7.1.32) (CK); Ethanolamine kinase (EC 2.7.1.82) (EK)].

UBP34_MOUSE
NC score	0.009982 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.009925 (rank : 14)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

MY18A_MOUSE
NC score	0.007626 (rank : 15)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1989	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
NC score	0.006803 (rank : 16)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1929	Shared Neighborhood Hits	5
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).