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Network neighborhood for query Sequence : CH60_MOUSE

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CH60_MOUSE
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CH60_HUMAN
θ value	0 (rank : 1)	NC score	0.994451 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

TCPB_HUMAN
θ value	4.02038e-16 (rank : 3)	NC score	0.675850 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPD_HUMAN
θ value	1.52774e-15 (rank : 4)	NC score	0.668251 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
θ value	1.99529e-15 (rank : 5)	NC score	0.667744 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPB_MOUSE
θ value	2.60593e-15 (rank : 6)	NC score	0.672122 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPH_HUMAN
θ value	1.42992e-13 (rank : 7)	NC score	0.656287 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
θ value	4.16044e-13 (rank : 8)	NC score	0.653368 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPE_MOUSE
θ value	6.00763e-12 (rank : 9)	NC score	0.647267 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
θ value	1.74796e-11 (rank : 10)	NC score	0.643881 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPW_HUMAN
θ value	1.47974e-10 (rank : 11)	NC score	0.615777 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPG_MOUSE
θ value	3.29651e-10 (rank : 12)	NC score	0.621126 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPW_MOUSE
θ value	5.62301e-10 (rank : 13)	NC score	0.610211 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPA2_MOUSE
θ value	9.59137e-10 (rank : 14)	NC score	0.626128 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA1_MOUSE
θ value	3.64472e-09 (rank : 15)	NC score	0.623154 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPG_HUMAN
θ value	1.06045e-08 (rank : 16)	NC score	0.613395 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPA_HUMAN
θ value	8.97725e-08 (rank : 17)	NC score	0.615934 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPZ_HUMAN
θ value	4.1701e-05 (rank : 18)	NC score	0.599406 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
θ value	4.1701e-05 (rank : 19)	NC score	0.599928 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPQ_MOUSE
θ value	0.00665767 (rank : 20)	NC score	0.552808 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPQ_HUMAN
θ value	0.0193708 (rank : 21)	NC score	0.551329 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

EEA1_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.024529 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MY18A_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.022805 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	1929	Shared Neighborhood Hits	17
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EEA1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.021615 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	1796	Shared Neighborhood Hits	16
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

BBS10_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.258343 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

MY18A_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.021148 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	1989	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.019271 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	1829	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RYR2_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.021791 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RAD17_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.028509 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

ALAT2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.015103 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

MACF1_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.018833 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	1341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.021662 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYH13_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.016560 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH9_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.017059 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	1762	Shared Neighborhood Hits	16
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KI21B_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.015348 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1017	Shared Neighborhood Hits	17
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.015704 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	997	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

LMNB1_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.012039 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

SF3B1_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.010668 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	352	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TMCC1_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.016509 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TNIP3_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.018972 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

ZN326_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.020151 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

ASB6_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.004997 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CENPF_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.014184 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	1932	Shared Neighborhood Hits	18
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

BBS10_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.189769 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.111957 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.112329 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

MKKS_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.214362 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

MKKS_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.237603 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

Hits sorted by NC score

CH60_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

CH60_HUMAN
NC score	0.994451 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

TCPB_HUMAN
NC score	0.675850 (rank : 3)	θ value	4.02038e-16 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_MOUSE
NC score	0.672122 (rank : 4)	θ value	2.60593e-15 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPD_HUMAN
NC score	0.668251 (rank : 5)	θ value	1.52774e-15 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
NC score	0.667744 (rank : 6)	θ value	1.99529e-15 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPH_HUMAN
NC score	0.656287 (rank : 7)	θ value	1.42992e-13 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
NC score	0.653368 (rank : 8)	θ value	4.16044e-13 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPE_MOUSE
NC score	0.647267 (rank : 9)	θ value	6.00763e-12 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
NC score	0.643881 (rank : 10)	θ value	1.74796e-11 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPA2_MOUSE
NC score	0.626128 (rank : 11)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA1_MOUSE
NC score	0.623154 (rank : 12)	θ value	3.64472e-09 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPG_MOUSE
NC score	0.621126 (rank : 13)	θ value	3.29651e-10 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPA_HUMAN
NC score	0.615934 (rank : 14)	θ value	8.97725e-08 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPW_HUMAN
NC score	0.615777 (rank : 15)	θ value	1.47974e-10 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPG_HUMAN
NC score	0.613395 (rank : 16)	θ value	1.06045e-08 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPW_MOUSE
NC score	0.610211 (rank : 17)	θ value	5.62301e-10 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPZ_MOUSE
NC score	0.599928 (rank : 18)	θ value	4.1701e-05 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
NC score	0.599406 (rank : 19)	θ value	4.1701e-05 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPQ_MOUSE
NC score	0.552808 (rank : 20)	θ value	0.00665767 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPQ_HUMAN
NC score	0.551329 (rank : 21)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

BBS10_HUMAN
NC score	0.258343 (rank : 22)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

MKKS_MOUSE
NC score	0.237603 (rank : 23)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

MKKS_HUMAN
NC score	0.214362 (rank : 24)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

BBS10_MOUSE
NC score	0.189769 (rank : 25)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_MOUSE
NC score	0.112329 (rank : 26)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.111957 (rank : 27)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RAD17_HUMAN
NC score	0.028509 (rank : 28)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

EEA1_MOUSE
NC score	0.024529 (rank : 29)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MY18A_HUMAN
NC score	0.022805 (rank : 30)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	1929	Shared Neighborhood Hits	17
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RYR2_HUMAN
NC score	0.021791 (rank : 31)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

MACF4_HUMAN
NC score	0.021662 (rank : 32)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

EEA1_HUMAN
NC score	0.021615 (rank : 33)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	1796	Shared Neighborhood Hits	16
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

MY18A_MOUSE
NC score	0.021148 (rank : 34)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	1989	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ZN326_HUMAN
NC score	0.020151 (rank : 35)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

MYH9_MOUSE
NC score	0.019271 (rank : 36)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	1829	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TNIP3_HUMAN
NC score	0.018972 (rank : 37)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

MACF1_HUMAN
NC score	0.018833 (rank : 38)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	1341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYH9_HUMAN
NC score	0.017059 (rank : 39)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	1762	Shared Neighborhood Hits	16
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH13_HUMAN
NC score	0.016560 (rank : 40)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

TMCC1_MOUSE
NC score	0.016509 (rank : 41)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

KI21B_MOUSE
NC score	0.015704 (rank : 42)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	997	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KI21B_HUMAN
NC score	0.015348 (rank : 43)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	1017	Shared Neighborhood Hits	17
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

ALAT2_HUMAN
NC score	0.015103 (rank : 44)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD30, Q8N9E2	Gene names	GPT2, AAT2
Domain Architecture	No domain graphic available
Description	Alanine aminotransferase 2 (EC 2.6.1.2) (ALT2) (Glutamic--pyruvic transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2).

CENPF_HUMAN
NC score	0.014184 (rank : 45)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1932	Shared Neighborhood Hits	18
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LMNB1_HUMAN
NC score	0.012039 (rank : 46)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

SF3B1_MOUSE
NC score	0.010668 (rank : 47)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	352	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ASB6_MOUSE
NC score	0.004997 (rank : 48)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).