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Network neighborhood for query Sequence : CH60_HUMAN

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CH60_HUMAN
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CH60_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
θ value	0 (rank : 2)	NC score	0.994451 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

TCPB_HUMAN
θ value	5.25075e-16 (rank : 3)	NC score	0.681663 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPD_HUMAN
θ value	1.52774e-15 (rank : 4)	NC score	0.673897 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
θ value	1.99529e-15 (rank : 5)	NC score	0.673408 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPB_MOUSE
θ value	3.40345e-15 (rank : 6)	NC score	0.677913 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPH_HUMAN
θ value	7.09661e-13 (rank : 7)	NC score	0.661641 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
θ value	1.58096e-12 (rank : 8)	NC score	0.658728 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPE_MOUSE
θ value	1.02475e-11 (rank : 9)	NC score	0.652848 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
θ value	6.64225e-11 (rank : 10)	NC score	0.649212 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPA2_MOUSE
θ value	2.52405e-10 (rank : 11)	NC score	0.633846 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPG_MOUSE
θ value	3.29651e-10 (rank : 12)	NC score	0.627780 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPA1_MOUSE
θ value	7.34386e-10 (rank : 13)	NC score	0.630847 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPZ_HUMAN
θ value	2.79066e-09 (rank : 14)	NC score	0.613745 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
θ value	2.79066e-09 (rank : 15)	NC score	0.614475 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPW_HUMAN
θ value	4.76016e-09 (rank : 16)	NC score	0.629049 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPG_HUMAN
θ value	1.06045e-08 (rank : 17)	NC score	0.620076 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPA_HUMAN
θ value	2.36244e-08 (rank : 18)	NC score	0.623696 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPW_MOUSE
θ value	3.08544e-08 (rank : 19)	NC score	0.623335 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPQ_HUMAN
θ value	0.0961366 (rank : 20)	NC score	0.551847 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPQ_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.553278 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

BBS10_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.262403 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

KI21B_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.014254 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	1017	Shared Neighborhood Hits	8
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.014318 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	997	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

VIGLN_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.021986 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

MACF1_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.007512 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	1341	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.008635 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	1321	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SIP1_MOUSE
θ value	6.88961 (rank : 28)	NC score	-0.000560 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

MYH9_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.003426 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	1829	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RAD17_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.022601 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

ZN326_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.016612 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

BBS10_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.194125 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.104492 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.104496 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

MKKS_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.212147 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

MKKS_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.240345 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

Hits sorted by NC score

CH60_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
NC score	0.994451 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

TCPB_HUMAN
NC score	0.681663 (rank : 3)	θ value	5.25075e-16 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_MOUSE
NC score	0.677913 (rank : 4)	θ value	3.40345e-15 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPD_HUMAN
NC score	0.673897 (rank : 5)	θ value	1.52774e-15 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
NC score	0.673408 (rank : 6)	θ value	1.99529e-15 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPH_HUMAN
NC score	0.661641 (rank : 7)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
NC score	0.658728 (rank : 8)	θ value	1.58096e-12 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPE_MOUSE
NC score	0.652848 (rank : 9)	θ value	1.02475e-11 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
NC score	0.649212 (rank : 10)	θ value	6.64225e-11 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPA2_MOUSE
NC score	0.633846 (rank : 11)	θ value	2.52405e-10 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA1_MOUSE
NC score	0.630847 (rank : 12)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPW_HUMAN
NC score	0.629049 (rank : 13)	θ value	4.76016e-09 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPG_MOUSE
NC score	0.627780 (rank : 14)	θ value	3.29651e-10 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPA_HUMAN
NC score	0.623696 (rank : 15)	θ value	2.36244e-08 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPW_MOUSE
NC score	0.623335 (rank : 16)	θ value	3.08544e-08 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPG_HUMAN
NC score	0.620076 (rank : 17)	θ value	1.06045e-08 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPZ_MOUSE
NC score	0.614475 (rank : 18)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
NC score	0.613745 (rank : 19)	θ value	2.79066e-09 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPQ_MOUSE
NC score	0.553278 (rank : 20)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPQ_HUMAN
NC score	0.551847 (rank : 21)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

BBS10_HUMAN
NC score	0.262403 (rank : 22)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

MKKS_MOUSE
NC score	0.240345 (rank : 23)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

MKKS_HUMAN
NC score	0.212147 (rank : 24)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

BBS10_MOUSE
NC score	0.194125 (rank : 25)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_MOUSE
NC score	0.104496 (rank : 26)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.104492 (rank : 27)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RAD17_HUMAN
NC score	0.022601 (rank : 28)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

VIGLN_HUMAN
NC score	0.021986 (rank : 29)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

ZN326_HUMAN
NC score	0.016612 (rank : 30)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

KI21B_MOUSE
NC score	0.014318 (rank : 31)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	997	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KI21B_HUMAN
NC score	0.014254 (rank : 32)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	1017	Shared Neighborhood Hits	8
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

MACF4_HUMAN
NC score	0.008635 (rank : 33)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	1321	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.007512 (rank : 34)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	1341	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYH9_MOUSE
NC score	0.003426 (rank : 35)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	1829	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SIP1_MOUSE
NC score	-0.000560 (rank : 36)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).