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Network neighborhood for query Sequence : CC45L_MOUSE

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CC45L_MOUSE
SwissProt Accessions	Q9Z1X9, O70547, Q9QUK1, Q9R212	Gene names	Cdc45l, Cdc45l2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CC45L_HUMAN
θ value	0 (rank : 1)	NC score	0.997810 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	O75419, O60856, Q6UW54, Q9UP68	Gene names	CDC45L, CDC45L2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1) (Cdc45).

CC45L_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z1X9, O70547, Q9QUK1, Q9R212	Gene names	Cdc45l, Cdc45l2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1).

MCM3_MOUSE
θ value	0.365318 (rank : 3)	NC score	0.052124 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

MCM3_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.051447 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

ECRG4_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.082357 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1Z8	Gene names	C2orf40, ECRG4
Domain Architecture	No domain graphic available
Description	Esophageal cancer related gene 4 protein precursor.

PKHA6_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.023302 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	556	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MACF4_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.010413 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1321	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

PAK7_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.003478 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

TF3C1_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.034028 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

3BHS2_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.011511 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P26149, Q8R0J6	Gene names	Hsd3b2
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

MY18A_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.004530 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	1989	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PKHA6_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.020193 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	591	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SPA3A_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.004964 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

ECRG4_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.038506 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LS0	Gene names
Domain Architecture	No domain graphic available
Description	Esophageal cancer related gene 4 protein precursor.

PAK7_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.002696 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

Hits sorted by NC score

CC45L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z1X9, O70547, Q9QUK1, Q9R212	Gene names	Cdc45l, Cdc45l2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1).

CC45L_HUMAN
NC score	0.997810 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	O75419, O60856, Q6UW54, Q9UP68	Gene names	CDC45L, CDC45L2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1) (Cdc45).

ECRG4_HUMAN
NC score	0.082357 (rank : 3)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1Z8	Gene names	C2orf40, ECRG4
Domain Architecture	No domain graphic available
Description	Esophageal cancer related gene 4 protein precursor.

MCM3_MOUSE
NC score	0.052124 (rank : 4)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

MCM3_HUMAN
NC score	0.051447 (rank : 5)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

ECRG4_MOUSE
NC score	0.038506 (rank : 6)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LS0	Gene names
Domain Architecture	No domain graphic available
Description	Esophageal cancer related gene 4 protein precursor.

TF3C1_MOUSE
NC score	0.034028 (rank : 7)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

PKHA6_HUMAN
NC score	0.023302 (rank : 8)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	556	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.020193 (rank : 9)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	591	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

3BHS2_MOUSE
NC score	0.011511 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P26149, Q8R0J6	Gene names	Hsd3b2
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II (3Beta-HSD II) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

MACF4_HUMAN
NC score	0.010413 (rank : 11)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	1321	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SPA3A_MOUSE
NC score	0.004964 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

MY18A_MOUSE
NC score	0.004530 (rank : 13)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1989	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PAK7_HUMAN
NC score	0.003478 (rank : 14)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PAK7_MOUSE
NC score	0.002696 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	875	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).