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Network neighborhood for query Sequence : TF3C1_MOUSE

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TF3C1_MOUSE
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TF3C1_HUMAN
θ value	0 (rank : 1)	NC score	0.973778 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TF3C1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

IWS1_MOUSE
θ value	0.00390308 (rank : 3)	NC score	0.075754 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	1258	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CN155_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.062287 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IWS1_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.053764 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NPBL_MOUSE
θ value	0.47712 (rank : 6)	NC score	0.046421 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NFH_MOUSE
θ value	0.62314 (rank : 7)	NC score	0.027222 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	2247	Shared Neighborhood Hits	49
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RFIP5_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.035538 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

LRC59_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.025888 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	398	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

MAGI1_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.027212 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	388	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.027483 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

CDC37_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.047524 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

GLU2B_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.038483 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

NKX12_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.011192 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).

SF3B1_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.046084 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.046080 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ZBT37_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.005462 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

T2_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.050139 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

EHMT2_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.014924 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.016162 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MFAP1_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.048996 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.041815 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

RBM25_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.026670 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	682	Shared Neighborhood Hits	22
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TNIK_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.007896 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	1570	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

A4_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.027827 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	16
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.028109 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

GPTC8_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.047527 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

M4K4_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.007462 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	1589	Shared Neighborhood Hits	24
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINT_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.034460 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	1514	Shared Neighborhood Hits	44
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PPIL2_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.037218 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q13356, Q13357, Q8TAH2, Q9BWR8	Gene names	PPIL2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

RN168_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.023221 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRHY_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.013577 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	1385	Shared Neighborhood Hits	27
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WNK1_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.007346 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CABYR_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.028670 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CAF1A_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.024305 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	736	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CC45L_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.035833 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75419, O60856, Q6UW54, Q9UP68	Gene names	CDC45L, CDC45L2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1) (Cdc45).

CDC37_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.044515 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	359	Shared Neighborhood Hits	25
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

FA98B_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.053600 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q52LJ0, Q8N935	Gene names	FAM98B
Domain Architecture	No domain graphic available
Description	Protein FAM98B.

LRC59_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.021796 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	415	Shared Neighborhood Hits	13
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

PPIL2_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.035333 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

XE7_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.021129 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	738	Shared Neighborhood Hits	19
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

CC45L_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.034028 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1X9, O70547, Q9QUK1, Q9R212	Gene names	Cdc45l, Cdc45l2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1).

CS007_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.023831 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	401	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DDX23_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.008914 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	486	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

MINT_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.037354 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	1291	Shared Neighborhood Hits	41
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PPCKC_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.016327 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2V4, Q3UEH3	Gene names	Pck1, Pepck
Domain Architecture
Description	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase) (PEPCK-C).

SON_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.021840 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	957	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

STK10_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.007497 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	1921	Shared Neighborhood Hits	40
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TGON2_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.031141 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZC313_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.037314 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	772	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ACINU_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.035100 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BAZ1B_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.021178 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	701	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CALD1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019120 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

FA98B_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.025262 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q80VD1, Q9CS28, Q9CS37	Gene names	Fam98b
Domain Architecture	No domain graphic available
Description	Protein FAM98B.

FANCE_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.028752 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

PAR3L_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.014812 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	297	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PELP1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.028678 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SAFB2_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.025621 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

CCL21_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.014989 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	O00585	Gene names	CCL21, SCYA21
Domain Architecture
Description	Small inducible cytokine A21 precursor (CCL21) (Beta chemokine exodus- 2) (6Ckine) (Secondary lymphoid-tissue chemokine) (SLC).

CGRE1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.034725 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

GRIN1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.018035 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MAP4_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.020667 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	409	Shared Neighborhood Hits	18
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MEFV_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.005539 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MYO6_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.005207 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

PGCA_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.007951 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

S6A11_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.006558 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

SAKS1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.016844 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SAS10_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.018766 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

WWC3_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.016227 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

ARI4A_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.020769 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CAH9_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.007263 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

CD008_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.019154 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CTRO_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.005484 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	2092	Shared Neighborhood Hits	38
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.007069 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	2344	Shared Neighborhood Hits	43
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

E41L1_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.006835 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

ELF4_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.007413 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

H10_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.019662 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	P10922	Gene names	H1f0, H1fv
Domain Architecture
Description	Histone H1' (H1.0) (H1(0)).

INCE_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.011246 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	978	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

ITSN1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.010453 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	1757	Shared Neighborhood Hits	45
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KBTBA_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.006548 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

LTB1L_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.004701 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	553	Shared Neighborhood Hits	10
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.004333 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	502	Shared Neighborhood Hits	9
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MASTL_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.003743 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	894	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MLL3_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.015153 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MTO1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.013292 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z3, Q9D2Q5	Gene names	Mto1
Domain Architecture	No domain graphic available
Description	Protein MTO1 homolog, mitochondrial precursor.

PELP1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.025134 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RN146_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.014090 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RRBP1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.014274 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	1650	Shared Neighborhood Hits	49
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SAFB2_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.018145 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	720	Shared Neighborhood Hits	21
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

TOP1_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.018422 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZFP91_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.003245 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).

ZFP91_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.002576 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	742	Shared Neighborhood Hits	9
SwissProt Accessions	Q62511, Q8BPY3, Q8C2B4	Gene names	Zfp91, Pzf
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 (Zfp-91) (Zinc finger protein PZF) (Penta Zf protein).

Hits sorted by NC score

TF3C1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TF3C1_HUMAN
NC score	0.973778 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

IWS1_MOUSE
NC score	0.075754 (rank : 3)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	1258	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CN155_HUMAN
NC score	0.062287 (rank : 4)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	385	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IWS1_HUMAN
NC score	0.053764 (rank : 5)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

FA98B_HUMAN
NC score	0.053600 (rank : 6)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q52LJ0, Q8N935	Gene names	FAM98B
Domain Architecture	No domain graphic available
Description	Protein FAM98B.

T2_MOUSE
NC score	0.050139 (rank : 7)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

MFAP1_HUMAN
NC score	0.048996 (rank : 8)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

GPTC8_HUMAN
NC score	0.047527 (rank : 9)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CDC37_HUMAN
NC score	0.047524 (rank : 10)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

NPBL_MOUSE
NC score	0.046421 (rank : 11)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SF3B1_HUMAN
NC score	0.046084 (rank : 12)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.046080 (rank : 13)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CDC37_MOUSE
NC score	0.044515 (rank : 14)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	359	Shared Neighborhood Hits	25
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

MFAP1_MOUSE
NC score	0.041815 (rank : 15)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

GLU2B_HUMAN
NC score	0.038483 (rank : 16)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MINT_HUMAN
NC score	0.037354 (rank : 17)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	1291	Shared Neighborhood Hits	41
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZC313_HUMAN
NC score	0.037314 (rank : 18)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	772	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

PPIL2_HUMAN
NC score	0.037218 (rank : 19)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q13356, Q13357, Q8TAH2, Q9BWR8	Gene names	PPIL2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

CC45L_HUMAN
NC score	0.035833 (rank : 20)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75419, O60856, Q6UW54, Q9UP68	Gene names	CDC45L, CDC45L2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1) (Cdc45).

RFIP5_MOUSE
NC score	0.035538 (rank : 21)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

PPIL2_MOUSE
NC score	0.035333 (rank : 22)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

ACINU_HUMAN
NC score	0.035100 (rank : 23)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CGRE1_HUMAN
NC score	0.034725 (rank : 24)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

MINT_MOUSE
NC score	0.034460 (rank : 25)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	1514	Shared Neighborhood Hits	44
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CC45L_MOUSE
NC score	0.034028 (rank : 26)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1X9, O70547, Q9QUK1, Q9R212	Gene names	Cdc45l, Cdc45l2
Domain Architecture
Description	CDC45-related protein (PORC-PI-1).

TGON2_HUMAN
NC score	0.031141 (rank : 27)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

FANCE_HUMAN
NC score	0.028752 (rank : 28)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

PELP1_HUMAN
NC score	0.028678 (rank : 29)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CABYR_HUMAN
NC score	0.028670 (rank : 30)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

A4_MOUSE
NC score	0.028109 (rank : 31)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_HUMAN
NC score	0.027827 (rank : 32)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	16
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

MAGI1_MOUSE
NC score	0.027483 (rank : 33)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

NFH_MOUSE
NC score	0.027222 (rank : 34)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	2247	Shared Neighborhood Hits	49
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAGI1_HUMAN
NC score	0.027212 (rank : 35)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	388	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

RBM25_HUMAN
NC score	0.026670 (rank : 36)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	682	Shared Neighborhood Hits	22
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

LRC59_HUMAN
NC score	0.025888 (rank : 37)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	398	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

SAFB2_MOUSE
NC score	0.025621 (rank : 38)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

FA98B_MOUSE
NC score	0.025262 (rank : 39)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q80VD1, Q9CS28, Q9CS37	Gene names	Fam98b
Domain Architecture	No domain graphic available
Description	Protein FAM98B.

PELP1_MOUSE
NC score	0.025134 (rank : 40)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CAF1A_MOUSE
NC score	0.024305 (rank : 41)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	736	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CS007_HUMAN
NC score	0.023831 (rank : 42)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	401	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

RN168_MOUSE
NC score	0.023221 (rank : 43)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SON_MOUSE
NC score	0.021840 (rank : 44)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	957	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

LRC59_MOUSE
NC score	0.021796 (rank : 45)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	415	Shared Neighborhood Hits	13
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

BAZ1B_HUMAN
NC score	0.021178 (rank : 46)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	701	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

XE7_HUMAN
NC score	0.021129 (rank : 47)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	738	Shared Neighborhood Hits	19
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ARI4A_HUMAN
NC score	0.020769 (rank : 48)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

MAP4_MOUSE
NC score	0.020667 (rank : 49)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	409	Shared Neighborhood Hits	18
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

H10_MOUSE
NC score	0.019662 (rank : 50)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	P10922	Gene names	H1f0, H1fv
Domain Architecture
Description	Histone H1' (H1.0) (H1(0)).

CD008_HUMAN
NC score	0.019154 (rank : 51)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CALD1_HUMAN
NC score	0.019120 (rank : 52)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SAS10_MOUSE
NC score	0.018766 (rank : 53)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

TOP1_MOUSE
NC score	0.018422 (rank : 54)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

SAFB2_HUMAN
NC score	0.018145 (rank : 55)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	720	Shared Neighborhood Hits	21
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

GRIN1_HUMAN
NC score	0.018035 (rank : 56)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SAKS1_HUMAN
NC score	0.016844 (rank : 57)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

PPCKC_MOUSE
NC score	0.016327 (rank : 58)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2V4, Q3UEH3	Gene names	Pck1, Pepck
Domain Architecture
Description	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (EC 4.1.1.32) (Phosphoenolpyruvate carboxylase) (PEPCK-C).

WWC3_HUMAN
NC score	0.016227 (rank : 59)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

EHMT2_MOUSE
NC score	0.016162 (rank : 60)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MLL3_MOUSE
NC score	0.015153 (rank : 61)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CCL21_HUMAN
NC score	0.014989 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	O00585	Gene names	CCL21, SCYA21
Domain Architecture
Description	Small inducible cytokine A21 precursor (CCL21) (Beta chemokine exodus- 2) (6Ckine) (Secondary lymphoid-tissue chemokine) (SLC).

EHMT2_HUMAN
NC score	0.014924 (rank : 63)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PAR3L_HUMAN
NC score	0.014812 (rank : 64)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	297	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

RRBP1_MOUSE
NC score	0.014274 (rank : 65)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	1650	Shared Neighborhood Hits	49
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RN146_HUMAN
NC score	0.014090 (rank : 66)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRHY_HUMAN
NC score	0.013577 (rank : 67)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	1385	Shared Neighborhood Hits	27
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MTO1_MOUSE
NC score	0.013292 (rank : 68)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z3, Q9D2Q5	Gene names	Mto1
Domain Architecture	No domain graphic available
Description	Protein MTO1 homolog, mitochondrial precursor.

INCE_HUMAN
NC score	0.011246 (rank : 69)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	978	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

NKX12_MOUSE
NC score	0.011192 (rank : 70)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).

ITSN1_HUMAN
NC score	0.010453 (rank : 71)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	1757	Shared Neighborhood Hits	45
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

DDX23_HUMAN
NC score	0.008914 (rank : 72)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	486	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

PGCA_HUMAN
NC score	0.007951 (rank : 73)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TNIK_HUMAN
NC score	0.007896 (rank : 74)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	1570	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

STK10_HUMAN
NC score	0.007497 (rank : 75)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	1921	Shared Neighborhood Hits	40
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

M4K4_HUMAN
NC score	0.007462 (rank : 76)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	1589	Shared Neighborhood Hits	24
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

ELF4_MOUSE
NC score	0.007413 (rank : 77)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

WNK1_HUMAN
NC score	0.007346 (rank : 78)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CAH9_HUMAN
NC score	0.007263 (rank : 79)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

CTRO_MOUSE
NC score	0.007069 (rank : 80)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	2344	Shared Neighborhood Hits	43
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

E41L1_MOUSE
NC score	0.006835 (rank : 81)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

S6A11_MOUSE
NC score	0.006558 (rank : 82)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

KBTBA_HUMAN
NC score	0.006548 (rank : 83)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

MEFV_HUMAN
NC score	0.005539 (rank : 84)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

CTRO_HUMAN
NC score	0.005484 (rank : 85)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	2092	Shared Neighborhood Hits	38
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ZBT37_HUMAN
NC score	0.005462 (rank : 86)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

MYO6_MOUSE
NC score	0.005207 (rank : 87)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

LTB1L_HUMAN
NC score	0.004701 (rank : 88)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	553	Shared Neighborhood Hits	10
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.004333 (rank : 89)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	502	Shared Neighborhood Hits	9
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MASTL_HUMAN
NC score	0.003743 (rank : 90)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	894	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

ZFP91_HUMAN
NC score	0.003245 (rank : 91)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).

ZFP91_MOUSE
NC score	0.002576 (rank : 92)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	742	Shared Neighborhood Hits	9
SwissProt Accessions	Q62511, Q8BPY3, Q8C2B4	Gene names	Zfp91, Pzf
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 (Zfp-91) (Zinc finger protein PZF) (Penta Zf protein).