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Network neighborhood for query Sequence : AP4A_MOUSE

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AP4A_MOUSE
SwissProt Accessions	P56380, Q9D2U6, Q9D6V2	Gene names	Nudt2, Apah1
Domain Architecture	No domain graphic available
Description	Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AP4A_MOUSE
θ value	1.22964e-73 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P56380, Q9D2U6, Q9D6V2	Gene names	Nudt2, Apah1
Domain Architecture	No domain graphic available
Description	Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2).

AP4A_HUMAN
θ value	3.95564e-72 (rank : 2)	NC score	0.957288 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	P50583	Gene names	NUDT2, APAH1
Domain Architecture
Description	Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2).

NUDT6_HUMAN
θ value	0.0113563 (rank : 3)	NC score	0.209899 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P53370, O95097, Q9UQD9	Gene names	NUDT6, FGF2AS
Domain Architecture
Description	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (Protein GFG) (GFG-1) (Antisense basic fibroblast growth factor).

NUD17_MOUSE
θ value	0.125558 (rank : 4)	NC score	0.166462 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CWD3, Q3URR9	Gene names	Nudt17
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 17, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 17).

NUDT6_MOUSE
θ value	0.163984 (rank : 5)	NC score	0.190200 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH40, Q8R2T3	Gene names	Nudt6, Asfgf2b
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (Antisense basic fibroblast growth factor B).

NUDT8_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.093956 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CR24, Q3TDQ2	Gene names	Nudt8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

NUDT8_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.063851 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

NUD15_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.087560 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BG93	Gene names	Nudt15, Mth2
Domain Architecture	No domain graphic available
Description	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 (EC 3.1.6.-) (8-oxo-dGTPase NUDT15) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15) (MutT homolog 2) (mMTH2).

PGBM_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.009003 (rank : 17)
Query Neighborhood Hits	10	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NUD15_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.075515 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NV35, Q6P2C9	Gene names	NUDT15
Domain Architecture	No domain graphic available
Description	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 (EC 3.1.6.-) (8-oxo-dGTPase NUDT15) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15).

NUD10_HUMAN
θ value	θ > 10 (rank : 11)	NC score	0.054016 (rank : 13)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFP7, Q86VK1, Q86VR0	Gene names	NUDT10, APS2, DIPP3A
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 3 alpha (EC 3.6.1.52) (DIPP-3 alpha) (DIPP3 alpha) (hDIPP3alpha) (Diadenosine 5',5'''-P1,P6- hexaphosphate hydrolase 3 alpha) (EC 3.6.1.-) (Nucleoside diphosphate- linked moiety X motif 10) (Nudix motif 10) (hAps2).

NUD11_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.053856 (rank : 14)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q96G61, Q9NVN0	Gene names	NUDT11, APS1, DIPP3B
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 3 beta (EC 3.6.1.52) (DIPP-3 beta) (DIPP3 beta) (hDIPP3beta) (Diadenosine 5',5'''-P1,P6- hexaphosphate hydrolase 3 beta) (EC 3.6.1.-) (Nucleoside diphosphate- linked moiety X motif 11) (Nudix motif 11) (hAps1).

NUD17_HUMAN
θ value	θ > 10 (rank : 13)	NC score	0.104013 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P0C025	Gene names	NUDT17
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 17, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 17).

NUDT3_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.060418 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O95989	Gene names	NUDT3, DIPP, DIPP1
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 1 (EC 3.6.1.52) (DIPP-1) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3).

NUDT3_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.056975 (rank : 12)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI46, Q6PG02, Q8BV71	Gene names	Nudt3, Dipp, Dipp1
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 1 (EC 3.6.1.52) (DIPP-1) (muDIPP1) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3).

NUDT4_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.051515 (rank : 15)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZJ9, Q53EZ2, Q68DD7, Q9NPC5, Q9NS30, Q9NZK0, Q9NZK1	Gene names	NUDT4, DIPP2
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 2 (EC 3.6.1.52) (DIPP-2) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4).

NUDT4_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.051452 (rank : 16)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2U6, Q8BXB9, Q9D3T6	Gene names	Nudt4, Dipp2
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 2 (EC 3.6.1.52) (DIPP-2) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4).

Hits sorted by NC score

AP4A_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.22964e-73 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P56380, Q9D2U6, Q9D6V2	Gene names	Nudt2, Apah1
Domain Architecture	No domain graphic available
Description	Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2).

AP4A_HUMAN
NC score	0.957288 (rank : 2)	θ value	3.95564e-72 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	P50583	Gene names	NUDT2, APAH1
Domain Architecture
Description	Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2).

NUDT6_HUMAN
NC score	0.209899 (rank : 3)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P53370, O95097, Q9UQD9	Gene names	NUDT6, FGF2AS
Domain Architecture
Description	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (Protein GFG) (GFG-1) (Antisense basic fibroblast growth factor).

NUDT6_MOUSE
NC score	0.190200 (rank : 4)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH40, Q8R2T3	Gene names	Nudt6, Asfgf2b
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (Antisense basic fibroblast growth factor B).

NUD17_MOUSE
NC score	0.166462 (rank : 5)	θ value	0.125558 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CWD3, Q3URR9	Gene names	Nudt17
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 17, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 17).

NUD17_HUMAN
NC score	0.104013 (rank : 6)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P0C025	Gene names	NUDT17
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 17, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 17).

NUDT8_MOUSE
NC score	0.093956 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CR24, Q3TDQ2	Gene names	Nudt8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

NUD15_MOUSE
NC score	0.087560 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BG93	Gene names	Nudt15, Mth2
Domain Architecture	No domain graphic available
Description	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 (EC 3.1.6.-) (8-oxo-dGTPase NUDT15) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15) (MutT homolog 2) (mMTH2).

NUD15_HUMAN
NC score	0.075515 (rank : 9)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NV35, Q6P2C9	Gene names	NUDT15
Domain Architecture	No domain graphic available
Description	Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 (EC 3.1.6.-) (8-oxo-dGTPase NUDT15) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15).

NUDT8_HUMAN
NC score	0.063851 (rank : 10)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

NUDT3_HUMAN
NC score	0.060418 (rank : 11)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O95989	Gene names	NUDT3, DIPP, DIPP1
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 1 (EC 3.6.1.52) (DIPP-1) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3).

NUDT3_MOUSE
NC score	0.056975 (rank : 12)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI46, Q6PG02, Q8BV71	Gene names	Nudt3, Dipp, Dipp1
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 1 (EC 3.6.1.52) (DIPP-1) (muDIPP1) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3).

NUD10_HUMAN
NC score	0.054016 (rank : 13)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFP7, Q86VK1, Q86VR0	Gene names	NUDT10, APS2, DIPP3A
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 3 alpha (EC 3.6.1.52) (DIPP-3 alpha) (DIPP3 alpha) (hDIPP3alpha) (Diadenosine 5',5'''-P1,P6- hexaphosphate hydrolase 3 alpha) (EC 3.6.1.-) (Nucleoside diphosphate- linked moiety X motif 10) (Nudix motif 10) (hAps2).

NUD11_HUMAN
NC score	0.053856 (rank : 14)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q96G61, Q9NVN0	Gene names	NUDT11, APS1, DIPP3B
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 3 beta (EC 3.6.1.52) (DIPP-3 beta) (DIPP3 beta) (hDIPP3beta) (Diadenosine 5',5'''-P1,P6- hexaphosphate hydrolase 3 beta) (EC 3.6.1.-) (Nucleoside diphosphate- linked moiety X motif 11) (Nudix motif 11) (hAps1).

NUDT4_HUMAN
NC score	0.051515 (rank : 15)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZJ9, Q53EZ2, Q68DD7, Q9NPC5, Q9NS30, Q9NZK0, Q9NZK1	Gene names	NUDT4, DIPP2
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 2 (EC 3.6.1.52) (DIPP-2) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4).

NUDT4_MOUSE
NC score	0.051452 (rank : 16)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2U6, Q8BXB9, Q9D3T6	Gene names	Nudt4, Dipp2
Domain Architecture	No domain graphic available
Description	Diphosphoinositol polyphosphate phosphohydrolase 2 (EC 3.6.1.52) (DIPP-2) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4).

PGBM_HUMAN
NC score	0.009003 (rank : 17)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).