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Network neighborhood for query Sequence : ADO_HUMAN

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ADO_HUMAN
SwissProt Accessions	Q06278, O14765, Q9UPG6	Gene names	AOX1, AO
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ADO_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q06278, O14765, Q9UPG6	Gene names	AOX1, AO
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1).

ADO_MOUSE
θ value	0 (rank : 2)	NC score	0.997812 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	O54754, Q9WU85, Q9Z2Z5	Gene names	Aox1, Ao, Ro
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1) (Retinal oxidase).

XDH_HUMAN
θ value	0 (rank : 3)	NC score	0.985584 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P47989, Q16681, Q16712, Q4PJ16	Gene names	XDH, XDHA
Domain Architecture
Description	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC 1.17.1.4) (XD); Xanthine oxidase (EC 1.17.3.2) (XO) (Xanthine oxidoreductase)].

XDH_MOUSE
θ value	0 (rank : 4)	NC score	0.985240 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q00519	Gene names	Xdh
Domain Architecture
Description	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC 1.17.1.4) (XD); Xanthine oxidase (EC 1.17.3.2) (XO) (Xanthine oxidoreductase)].

CR2_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.016714 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

KRA59_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.010205 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	310	Shared Neighborhood Hits	2
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

RHG26_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.009035 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	281	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

S39A5_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.017382 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

CP2S1_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.004164 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBX6	Gene names	Cyp2s1
Domain Architecture
Description	Cytochrome P450 2S1 (EC 1.14.14.1) (CYPIIS1).

I12R1_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.024312 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

ATS5_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.006228 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

AURKB_HUMAN
θ value	5.27518 (rank : 12)	NC score	-0.000036 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).

MEGF9_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.010709 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ATS5_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.005688 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

RGNEF_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.006049 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	641	Shared Neighborhood Hits	2
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

STTP1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.006492 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

Hits sorted by NC score

ADO_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q06278, O14765, Q9UPG6	Gene names	AOX1, AO
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1).

ADO_MOUSE
NC score	0.997812 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	O54754, Q9WU85, Q9Z2Z5	Gene names	Aox1, Ao, Ro
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1) (Retinal oxidase).

XDH_HUMAN
NC score	0.985584 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P47989, Q16681, Q16712, Q4PJ16	Gene names	XDH, XDHA
Domain Architecture
Description	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC 1.17.1.4) (XD); Xanthine oxidase (EC 1.17.3.2) (XO) (Xanthine oxidoreductase)].

XDH_MOUSE
NC score	0.985240 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q00519	Gene names	Xdh
Domain Architecture
Description	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (EC 1.17.1.4) (XD); Xanthine oxidase (EC 1.17.3.2) (XO) (Xanthine oxidoreductase)].

I12R1_MOUSE
NC score	0.024312 (rank : 5)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

S39A5_MOUSE
NC score	0.017382 (rank : 6)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

CR2_MOUSE
NC score	0.016714 (rank : 7)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

MEGF9_MOUSE
NC score	0.010709 (rank : 8)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA59_HUMAN
NC score	0.010205 (rank : 9)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	310	Shared Neighborhood Hits	2
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

RHG26_HUMAN
NC score	0.009035 (rank : 10)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	281	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

STTP1_MOUSE
NC score	0.006492 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	246	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

ATS5_HUMAN
NC score	0.006228 (rank : 12)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

RGNEF_MOUSE
NC score	0.006049 (rank : 13)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	641	Shared Neighborhood Hits	2
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ATS5_MOUSE
NC score	0.005688 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

CP2S1_MOUSE
NC score	0.004164 (rank : 15)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBX6	Gene names	Cyp2s1
Domain Architecture
Description	Cytochrome P450 2S1 (EC 1.14.14.1) (CYPIIS1).

AURKB_HUMAN
NC score	-0.000036 (rank : 16)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	847	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GD4, O14630, O60446, O95083, Q96DV5, Q9UQ46	Gene names	AURKB, AIK2, AIM1, ARK2, STK12
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1- related kinase 2) (Aurora-related kinase 2) (STK-1).