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Network neighborhood for query Sequence : XPOT_HUMAN

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XPOT_HUMAN
SwissProt Accessions	O43592, O43784, Q8WUG2, Q9BVS7	Gene names	XPOT
Domain Architecture
Description	Exportin-T (tRNA exportin) (Exportin(tRNA)).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

XPOT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O43592, O43784, Q8WUG2, Q9BVS7	Gene names	XPOT
Domain Architecture
Description	Exportin-T (tRNA exportin) (Exportin(tRNA)).

XPO5_HUMAN
θ value	5.62301e-10 (rank : 2)	NC score	0.401045 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAV4, Q5JTE6, Q96G48, Q96HN3, Q9BWM6, Q9BZV5, Q9H9M4, Q9NT89, Q9NW39, Q9ULC9	Gene names	XPO5, KIAA1291, RANBP21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

XPO5_MOUSE
θ value	2.79066e-09 (rank : 3)	NC score	0.394814 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q924C1, Q7TMP2, Q80TF9, Q9CRI9, Q9CT48	Gene names	Xpo5, Kiaa1291, Ranbp21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

XPO1_HUMAN
θ value	1.09739e-05 (rank : 4)	NC score	0.323899 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	O14980, Q63HP8, Q68CP3, Q99433	Gene names	XPO1, CRM1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

XPO1_MOUSE
θ value	1.09739e-05 (rank : 5)	NC score	0.324623 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5F9	Gene names	Xpo1, Crm1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

IPO13_MOUSE
θ value	0.0148317 (rank : 6)	NC score	0.198384 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0C1, Q6ZQ60	Gene names	Ipo13, Kiaa0724
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13).

IPO13_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.189790 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	O94829, Q7LC04, Q96HS3, Q9H8N3, Q9UFR1	Gene names	IPO13, KIAA0724, RANBP13
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13) (Ran-binding protein 13) (RanBP13) (Karyopherin 13) (Kap13).

TNPO3_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.162783 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5L0, Q6NUM1, Q96G71, Q96GU9, Q9Y3R2	Gene names	TNPO3, IPO12
Domain Architecture	No domain graphic available
Description	Transportin-3 (Transportin-SR) (TRN-SR) (Importin-12).

TNPO3_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.163192 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P2B1, Q7TSL6, Q8BKX4, Q8BP42	Gene names	Tnpo3
Domain Architecture	No domain graphic available
Description	Transportin-3.

VPS11_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.103260 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

COG4_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.077263 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1U1	Gene names	Cog4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

VPS11_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.091974 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

PARN_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.056187 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O95453	Gene names	PARN, DAN
Domain Architecture	No domain graphic available
Description	Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Polyadenylate- specific ribonuclease) (Deadenylating nuclease) (Deadenylation nuclease).

EXOC4_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.043872 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q96A65, Q9C0G4, Q9H9K0, Q9P102	Gene names	EXOC4, KIAA1699, SEC8, SEC8L1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

COG4_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.070161 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9E3, Q96D40, Q9BRF0, Q9BVZ2, Q9H5Y4, Q9Y3W3	Gene names	COG4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

RYR3_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.025637 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

PRKDC_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.018125 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

MACF1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.004571 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	1313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

PSMD2_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.016710 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

Hits sorted by NC score

XPOT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O43592, O43784, Q8WUG2, Q9BVS7	Gene names	XPOT
Domain Architecture
Description	Exportin-T (tRNA exportin) (Exportin(tRNA)).

XPO5_HUMAN
NC score	0.401045 (rank : 2)	θ value	5.62301e-10 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAV4, Q5JTE6, Q96G48, Q96HN3, Q9BWM6, Q9BZV5, Q9H9M4, Q9NT89, Q9NW39, Q9ULC9	Gene names	XPO5, KIAA1291, RANBP21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

XPO5_MOUSE
NC score	0.394814 (rank : 3)	θ value	2.79066e-09 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q924C1, Q7TMP2, Q80TF9, Q9CRI9, Q9CT48	Gene names	Xpo5, Kiaa1291, Ranbp21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

XPO1_MOUSE
NC score	0.324623 (rank : 4)	θ value	1.09739e-05 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5F9	Gene names	Xpo1, Crm1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

XPO1_HUMAN
NC score	0.323899 (rank : 5)	θ value	1.09739e-05 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	O14980, Q63HP8, Q68CP3, Q99433	Gene names	XPO1, CRM1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

IPO13_MOUSE
NC score	0.198384 (rank : 6)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0C1, Q6ZQ60	Gene names	Ipo13, Kiaa0724
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13).

IPO13_HUMAN
NC score	0.189790 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	O94829, Q7LC04, Q96HS3, Q9H8N3, Q9UFR1	Gene names	IPO13, KIAA0724, RANBP13
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13) (Ran-binding protein 13) (RanBP13) (Karyopherin 13) (Kap13).

TNPO3_MOUSE
NC score	0.163192 (rank : 8)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P2B1, Q7TSL6, Q8BKX4, Q8BP42	Gene names	Tnpo3
Domain Architecture	No domain graphic available
Description	Transportin-3.

TNPO3_HUMAN
NC score	0.162783 (rank : 9)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5L0, Q6NUM1, Q96G71, Q96GU9, Q9Y3R2	Gene names	TNPO3, IPO12
Domain Architecture	No domain graphic available
Description	Transportin-3 (Transportin-SR) (TRN-SR) (Importin-12).

VPS11_HUMAN
NC score	0.103260 (rank : 10)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
NC score	0.091974 (rank : 11)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

COG4_MOUSE
NC score	0.077263 (rank : 12)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1U1	Gene names	Cog4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

COG4_HUMAN
NC score	0.070161 (rank : 13)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9E3, Q96D40, Q9BRF0, Q9BVZ2, Q9H5Y4, Q9Y3W3	Gene names	COG4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

PARN_HUMAN
NC score	0.056187 (rank : 14)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O95453	Gene names	PARN, DAN
Domain Architecture	No domain graphic available
Description	Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Polyadenylate- specific ribonuclease) (Deadenylating nuclease) (Deadenylation nuclease).

EXOC4_HUMAN
NC score	0.043872 (rank : 15)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q96A65, Q9C0G4, Q9H9K0, Q9P102	Gene names	EXOC4, KIAA1699, SEC8, SEC8L1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

RYR3_HUMAN
NC score	0.025637 (rank : 16)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

PRKDC_MOUSE
NC score	0.018125 (rank : 17)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

PSMD2_MOUSE
NC score	0.016710 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

MACF1_MOUSE
NC score	0.004571 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	1313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).