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Network neighborhood for query Sequence : WBS27_HUMAN

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WBS27_HUMAN
SwissProt Accessions	Q8N6F8	Gene names	WBSCR27
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 27 protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WBS27_HUMAN
θ value	2.68277e-145 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6F8	Gene names	WBSCR27
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 27 protein.

WBS22_HUMAN
θ value	0.00175202 (rank : 2)	NC score	0.261165 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O43709, Q96P12, Q9BQ58, Q9HBP9	Gene names	WBSCR22
Domain Architecture
Description	Putative methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosome region 22 protein).

WBS22_MOUSE
θ value	0.0563607 (rank : 3)	NC score	0.229536 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CY21, Q3U915	Gene names	Wbscr22
Domain Architecture	No domain graphic available
Description	Putative methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosome region 22 protein homolog).

GNMT_HUMAN
θ value	0.0961366 (rank : 4)	NC score	0.157367 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q14749, Q9NNZ1, Q9NS24	Gene names	GNMT
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

ABCA2_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.019451 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

GNMT_MOUSE
θ value	2.36792 (rank : 6)	NC score	0.125700 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXF8, Q91WN7	Gene names	Gnmt
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

PTGIS_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.027630 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	O35074	Gene names	Ptgis, Cyp8
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

COQ3_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.076138 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.071378 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

PLPP_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.033258 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GD0, Q9UGY2	Gene names	PDXP, PLP, PLPP
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

THUM2_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.025178 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZB3	Gene names	Thumpd2
Domain Architecture
Description	THUMP domain-containing protein 2.

ZBT17_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.001113 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	925	Shared Neighborhood Hits	2
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

Hits sorted by NC score

WBS27_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.68277e-145 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6F8	Gene names	WBSCR27
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 27 protein.

WBS22_HUMAN
NC score	0.261165 (rank : 2)	θ value	0.00175202 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	O43709, Q96P12, Q9BQ58, Q9HBP9	Gene names	WBSCR22
Domain Architecture
Description	Putative methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosome region 22 protein).

WBS22_MOUSE
NC score	0.229536 (rank : 3)	θ value	0.0563607 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CY21, Q3U915	Gene names	Wbscr22
Domain Architecture	No domain graphic available
Description	Putative methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosome region 22 protein homolog).

GNMT_HUMAN
NC score	0.157367 (rank : 4)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q14749, Q9NNZ1, Q9NS24	Gene names	GNMT
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

GNMT_MOUSE
NC score	0.125700 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXF8, Q91WN7	Gene names	Gnmt
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

COQ3_HUMAN
NC score	0.076138 (rank : 6)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_MOUSE
NC score	0.071378 (rank : 7)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

PLPP_HUMAN
NC score	0.033258 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GD0, Q9UGY2	Gene names	PDXP, PLP, PLPP
Domain Architecture
Description	Pyridoxal phosphate phosphatase (EC 3.1.3.74) (PLP phosphatase).

PTGIS_MOUSE
NC score	0.027630 (rank : 9)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	O35074	Gene names	Ptgis, Cyp8
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

THUM2_MOUSE
NC score	0.025178 (rank : 10)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZB3	Gene names	Thumpd2
Domain Architecture
Description	THUMP domain-containing protein 2.

ABCA2_HUMAN
NC score	0.019451 (rank : 11)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ZBT17_HUMAN
NC score	0.001113 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	925	Shared Neighborhood Hits	2
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).