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Network neighborhood for query Sequence : VPS54_MOUSE

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VPS54_MOUSE
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VPS54_HUMAN
θ value	0 (rank : 1)	NC score	0.989587 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

VPS54_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

RBCC1_MOUSE
θ value	0.0148317 (rank : 3)	NC score	0.047389 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	1048	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

BPA1_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.030531 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	1477	Shared Neighborhood Hits	16
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PTN3_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.021849 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RAD50_HUMAN
θ value	0.163984 (rank : 6)	NC score	0.034119 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CD45_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.025781 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

TB22A_MOUSE
θ value	0.365318 (rank : 8)	NC score	0.061369 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

RRBP1_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.035419 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	1306	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

MYH11_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.017570 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1806	Shared Neighborhood Hits	17
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

TR10C_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.035744 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

NCOR2_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.035190 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

GP132_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.010644 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNW8, Q9BSU2	Gene names	GPR132, G2A
Domain Architecture
Description	Probable G-protein coupled receptor 132 (G2 accumulation protein).

ACINU_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.027515 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MCM3A_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.027247 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

EEA1_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.020116 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GRAP1_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.030099 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

RRBP1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.025815 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1650	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CENPE_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.019526 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	2060	Shared Neighborhood Hits	21
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CHD9_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.008467 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

PO121_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.017760 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	345	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SMC3_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.024861 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	1186	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.024854 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	1187	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

XRCC4_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.032585 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

MTAP_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.037068 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q13126, Q9H010	Gene names	MTAP, MSAP
Domain Architecture
Description	S-methyl-5-thioadenosine phosphorylase (EC 2.4.2.28) (5'- methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAPase).

NCOR2_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.027629 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	870	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NR1D1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.007195 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

VPS45_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.032529 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

VPS45_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.032603 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

IF4G1_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.011178 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MY116_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.024268 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

RIOK2_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.017216 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RP1L1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.018576 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	1072	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TLR3_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.004927 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	298	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

ZCH10_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.024747 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ARHG1_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.006877 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CIR_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.014608 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

DACH1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.015902 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DACH1_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.016306 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

HIP1R_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.027397 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	809	Shared Neighborhood Hits	15
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

K0562_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.013459 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

RHG08_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.012470 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG18_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.009032 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

SHCBP_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.014255 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z179, Q3UED9, Q3UMD9	Gene names	Shcbp1, Pal
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1 (Protein expressed in activated lymphocytes) (mPAL) (SHC-binding protein).

TRAF2_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.006939 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	394	Shared Neighborhood Hits	2
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

Hits sorted by NC score

VPS54_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

VPS54_HUMAN
NC score	0.989587 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

TB22A_MOUSE
NC score	0.061369 (rank : 3)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

RBCC1_MOUSE
NC score	0.047389 (rank : 4)	θ value	0.0148317 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	1048	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MTAP_HUMAN
NC score	0.037068 (rank : 5)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q13126, Q9H010	Gene names	MTAP, MSAP
Domain Architecture
Description	S-methyl-5-thioadenosine phosphorylase (EC 2.4.2.28) (5'- methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAPase).

TR10C_HUMAN
NC score	0.035744 (rank : 6)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

RRBP1_HUMAN
NC score	0.035419 (rank : 7)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	1306	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

NCOR2_MOUSE
NC score	0.035190 (rank : 8)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RAD50_HUMAN
NC score	0.034119 (rank : 9)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

VPS45_MOUSE
NC score	0.032603 (rank : 10)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	P97390, Q91VK9	Gene names	Vps45a, Vps45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (mVps45).

XRCC4_HUMAN
NC score	0.032585 (rank : 11)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

VPS45_HUMAN
NC score	0.032529 (rank : 12)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRW7, Q15715, Q9Y4Z6	Gene names	VPS45A, VPS45
Domain Architecture
Description	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45).

BPA1_MOUSE
NC score	0.030531 (rank : 13)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	1477	Shared Neighborhood Hits	16
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GRAP1_HUMAN
NC score	0.030099 (rank : 14)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

NCOR2_HUMAN
NC score	0.027629 (rank : 15)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	870	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ACINU_HUMAN
NC score	0.027515 (rank : 16)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

HIP1R_HUMAN
NC score	0.027397 (rank : 17)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	809	Shared Neighborhood Hits	15
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

MCM3A_MOUSE
NC score	0.027247 (rank : 18)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

RRBP1_MOUSE
NC score	0.025815 (rank : 19)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	1650	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CD45_MOUSE
NC score	0.025781 (rank : 20)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

SMC3_HUMAN
NC score	0.024861 (rank : 21)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	1186	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.024854 (rank : 22)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	1187	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ZCH10_HUMAN
NC score	0.024747 (rank : 23)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MY116_MOUSE
NC score	0.024268 (rank : 24)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

PTN3_HUMAN
NC score	0.021849 (rank : 25)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

EEA1_MOUSE
NC score	0.020116 (rank : 26)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CENPE_HUMAN
NC score	0.019526 (rank : 27)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	2060	Shared Neighborhood Hits	21
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RP1L1_HUMAN
NC score	0.018576 (rank : 28)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	1072	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PO121_MOUSE
NC score	0.017760 (rank : 29)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	345	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

MYH11_HUMAN
NC score	0.017570 (rank : 30)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	1806	Shared Neighborhood Hits	17
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RIOK2_HUMAN
NC score	0.017216 (rank : 31)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

DACH1_MOUSE
NC score	0.016306 (rank : 32)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DACH1_HUMAN
NC score	0.015902 (rank : 33)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

CIR_MOUSE
NC score	0.014608 (rank : 34)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SHCBP_MOUSE
NC score	0.014255 (rank : 35)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z179, Q3UED9, Q3UMD9	Gene names	Shcbp1, Pal
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1 (Protein expressed in activated lymphocytes) (mPAL) (SHC-binding protein).

K0562_HUMAN
NC score	0.013459 (rank : 36)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

RHG08_HUMAN
NC score	0.012470 (rank : 37)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

IF4G1_MOUSE
NC score	0.011178 (rank : 38)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

GP132_HUMAN
NC score	0.010644 (rank : 39)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	450	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNW8, Q9BSU2	Gene names	GPR132, G2A
Domain Architecture
Description	Probable G-protein coupled receptor 132 (G2 accumulation protein).

RHG18_MOUSE
NC score	0.009032 (rank : 40)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

CHD9_HUMAN
NC score	0.008467 (rank : 41)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

NR1D1_HUMAN
NC score	0.007195 (rank : 42)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

TRAF2_MOUSE
NC score	0.006939 (rank : 43)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	394	Shared Neighborhood Hits	2
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

ARHG1_MOUSE
NC score	0.006877 (rank : 44)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

TLR3_MOUSE
NC score	0.004927 (rank : 45)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	298	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).