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Network neighborhood for query Sequence : VACHT_HUMAN

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VACHT_HUMAN
SwissProt Accessions	Q16572	Gene names	SLC18A3, VACHT
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VACHT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q16572	Gene names	SLC18A3, VACHT
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

VACHT_MOUSE
θ value	0 (rank : 2)	NC score	0.997847 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

VMAT1_MOUSE
θ value	1.03855e-80 (rank : 3)	NC score	0.933271 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R090	Gene names	Slc18a1, Vmat1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

VMAT1_HUMAN
θ value	2.55803e-79 (rank : 4)	NC score	0.934888 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P54219	Gene names	SLC18A1, VMAT1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

VMAT2_MOUSE
θ value	7.44272e-79 (rank : 5)	NC score	0.935087 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BRU6, Q8CC55	Gene names	Slc18a2, Vmat2
Domain Architecture
Description	Synaptic vesicular amine transporter (Monoamine transporter) (Vesicular amine transporter 2) (VAT2) (Solute carrier family 18 member 2).

VMAT2_HUMAN
θ value	2.1655e-78 (rank : 6)	NC score	0.935847 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q05940, Q15876, Q9H3P6	Gene names	SLC18A2, SVMT, VMAT2
Domain Architecture
Description	Synaptic vesicular amine transporter (Monoamine transporter) (Vesicular amine transporter 2) (VAT2) (Solute carrier family 18 member 2).

ORCT2_HUMAN
θ value	0.0330416 (rank : 7)	NC score	0.124831 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q96BI1, O14906, O43562, O60485, O60680, Q7LDS5, Q7LGF7	Gene names	SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like protein 2 (Imprinted multi-membrane spanning polyspecific transporter-related protein 1) (Efflux transporter-like protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (Tumor-suppressing STF cDNA 5 protein) (Beckwith-Wiedemann syndrome chromosome region 1 candidate protein A) (p45-Beckwith-Wiedemann region 1 A) (p45-BWR1A) (Solute carrier family 22 member 18) (Solute carrier family 22 member 1-like).

ORCT2_MOUSE
θ value	0.0330416 (rank : 8)	NC score	0.122674 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q78KK3, O35428, O54959, O88283, Q99NF4	Gene names	Slc22a18, Impt1, Itm, Orctl2, Tssc5
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like protein 2 (Imprinted multi-membrane spanning polyspecific transporter-related protein 1) (Multi-membrane spanning polyspecific transporter) (Solute carrier family 22 member 18).

S17A5_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.087057 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BN82, Q3TE25	Gene names	Slc17a5
Domain Architecture
Description	Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter).

S17A5_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.114446 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRA2, Q8NBR5, Q9UGH0	Gene names	SLC17A5
Domain Architecture
Description	Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59).

MOT8_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.080931 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

NPT3_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.072056 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SZA1, Q8VCX8	Gene names	Slc17a2, Npt3
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 3 (Sodium/phosphate cotransporter 3) (Na(+)/PI cotransporter 3) (Solute carrier family 17 member 2).

MOT8_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.069385 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

PCSK4_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.012328 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

NPT3_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.060578 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O00624, Q5TB84	Gene names	SLC17A2, NPT3
Domain Architecture
Description	Sodium-dependent phosphate transport protein 3 (Sodium/phosphate cotransporter 3) (Na(+)/PI cotransporter 3) (Solute carrier family 17 member 2).

ARHG7_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.003739 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	347	Shared Neighborhood Hits	2
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

NPT4_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.052063 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	O00476	Gene names	SLC17A3, NPT4
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 4 (Sodium/phosphate cotransporter 4) (Na(+)/PI cotransporter 4) (Solute carrier family 17 member 3).

SV2A_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.031726 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q7L0J3, O94841, Q5QNX8, Q7Z3L6, Q8NBJ6, Q9BVZ9	Gene names	SV2A, KIAA0736
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2A.

SV2A_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.031717 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIS5, Q80TT0, Q8R0R5	Gene names	Sv2a, Kiaa0736, Sv2
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2A (Synaptic vesicle protein 2A) (Synaptic vesicle protein 2) (Calcium regulator SV2A).

G6PT1_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.089516 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	O43826, O96016, Q9UI19, Q9UNS4	Gene names	SLC37A4, G6PT, G6PT1
Domain Architecture	No domain graphic available
Description	Glucose-6-phosphate translocase (Glucose-5-phosphate transporter) (Solute carrier family 37 member 4).

MOT1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.052403 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P53985, Q9NSJ9	Gene names	SLC16A1, MCT1
Domain Architecture
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

MOT2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.055369 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	O60669, Q9UPB3	Gene names	SLC16A7, MCT2
Domain Architecture
Description	Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7).

Hits sorted by NC score

VACHT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q16572	Gene names	SLC18A3, VACHT
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

VACHT_MOUSE
NC score	0.997847 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

VMAT2_HUMAN
NC score	0.935847 (rank : 3)	θ value	2.1655e-78 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q05940, Q15876, Q9H3P6	Gene names	SLC18A2, SVMT, VMAT2
Domain Architecture
Description	Synaptic vesicular amine transporter (Monoamine transporter) (Vesicular amine transporter 2) (VAT2) (Solute carrier family 18 member 2).

VMAT2_MOUSE
NC score	0.935087 (rank : 4)	θ value	7.44272e-79 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BRU6, Q8CC55	Gene names	Slc18a2, Vmat2
Domain Architecture
Description	Synaptic vesicular amine transporter (Monoamine transporter) (Vesicular amine transporter 2) (VAT2) (Solute carrier family 18 member 2).

VMAT1_HUMAN
NC score	0.934888 (rank : 5)	θ value	2.55803e-79 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P54219	Gene names	SLC18A1, VMAT1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

VMAT1_MOUSE
NC score	0.933271 (rank : 6)	θ value	1.03855e-80 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R090	Gene names	Slc18a1, Vmat1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

ORCT2_HUMAN
NC score	0.124831 (rank : 7)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q96BI1, O14906, O43562, O60485, O60680, Q7LDS5, Q7LGF7	Gene names	SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like protein 2 (Imprinted multi-membrane spanning polyspecific transporter-related protein 1) (Efflux transporter-like protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (Tumor-suppressing STF cDNA 5 protein) (Beckwith-Wiedemann syndrome chromosome region 1 candidate protein A) (p45-Beckwith-Wiedemann region 1 A) (p45-BWR1A) (Solute carrier family 22 member 18) (Solute carrier family 22 member 1-like).

ORCT2_MOUSE
NC score	0.122674 (rank : 8)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q78KK3, O35428, O54959, O88283, Q99NF4	Gene names	Slc22a18, Impt1, Itm, Orctl2, Tssc5
Domain Architecture	No domain graphic available
Description	Organic cation transporter-like protein 2 (Imprinted multi-membrane spanning polyspecific transporter-related protein 1) (Multi-membrane spanning polyspecific transporter) (Solute carrier family 22 member 18).

S17A5_HUMAN
NC score	0.114446 (rank : 9)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRA2, Q8NBR5, Q9UGH0	Gene names	SLC17A5
Domain Architecture
Description	Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59).

G6PT1_HUMAN
NC score	0.089516 (rank : 10)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	O43826, O96016, Q9UI19, Q9UNS4	Gene names	SLC37A4, G6PT, G6PT1
Domain Architecture	No domain graphic available
Description	Glucose-6-phosphate translocase (Glucose-5-phosphate transporter) (Solute carrier family 37 member 4).

S17A5_MOUSE
NC score	0.087057 (rank : 11)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BN82, Q3TE25	Gene names	Slc17a5
Domain Architecture
Description	Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid cotransporter).

MOT8_HUMAN
NC score	0.080931 (rank : 12)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

NPT3_MOUSE
NC score	0.072056 (rank : 13)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SZA1, Q8VCX8	Gene names	Slc17a2, Npt3
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 3 (Sodium/phosphate cotransporter 3) (Na(+)/PI cotransporter 3) (Solute carrier family 17 member 2).

MOT8_MOUSE
NC score	0.069385 (rank : 14)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

NPT3_HUMAN
NC score	0.060578 (rank : 15)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O00624, Q5TB84	Gene names	SLC17A2, NPT3
Domain Architecture
Description	Sodium-dependent phosphate transport protein 3 (Sodium/phosphate cotransporter 3) (Na(+)/PI cotransporter 3) (Solute carrier family 17 member 2).

MOT2_HUMAN
NC score	0.055369 (rank : 16)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	O60669, Q9UPB3	Gene names	SLC16A7, MCT2
Domain Architecture
Description	Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7).

MOT1_HUMAN
NC score	0.052403 (rank : 17)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P53985, Q9NSJ9	Gene names	SLC16A1, MCT1
Domain Architecture
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

NPT4_HUMAN
NC score	0.052063 (rank : 18)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	O00476	Gene names	SLC17A3, NPT4
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 4 (Sodium/phosphate cotransporter 4) (Na(+)/PI cotransporter 4) (Solute carrier family 17 member 3).

SV2A_HUMAN
NC score	0.031726 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q7L0J3, O94841, Q5QNX8, Q7Z3L6, Q8NBJ6, Q9BVZ9	Gene names	SV2A, KIAA0736
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2A.

SV2A_MOUSE
NC score	0.031717 (rank : 20)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIS5, Q80TT0, Q8R0R5	Gene names	Sv2a, Kiaa0736, Sv2
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2A (Synaptic vesicle protein 2A) (Synaptic vesicle protein 2) (Calcium regulator SV2A).

PCSK4_HUMAN
NC score	0.012328 (rank : 21)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

ARHG7_HUMAN
NC score	0.003739 (rank : 22)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	347	Shared Neighborhood Hits	2
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).