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Network neighborhood for query Sequence : TR100_HUMAN

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TR100_HUMAN
SwissProt Accessions	O75448, Q14143, Q9NNY5	Gene names	THRAP4, ARC100, DRIP100, KIAA0130, TRAP100
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 100 kDa component (Trap100) (Thyroid hormone receptor-associated protein 4) (Vitamin D3 receptor-interacting protein complex component DRIP100) (Activator- recruited cofactor 100 kDa component) (ARC100).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TR100_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O75448, Q14143, Q9NNY5	Gene names	THRAP4, ARC100, DRIP100, KIAA0130, TRAP100
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 100 kDa component (Trap100) (Thyroid hormone receptor-associated protein 4) (Vitamin D3 receptor-interacting protein complex component DRIP100) (Activator- recruited cofactor 100 kDa component) (ARC100).

RHBD3_MOUSE
θ value	0.365318 (rank : 2)	NC score	0.112084 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

RHBD3_HUMAN
θ value	0.813845 (rank : 3)	NC score	0.103731 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

RT29_HUMAN
θ value	1.38821 (rank : 4)	NC score	0.055468 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P51398, Q13044, Q96Q20	Gene names	DAP3, MRPS29
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S29 (S29mt) (MRP-S29) (Death- associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein).

CO6A3_HUMAN
θ value	3.0926 (rank : 5)	NC score	0.016654 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

BPAEA_HUMAN
θ value	5.27518 (rank : 6)	NC score	0.008132 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	1369	Shared Neighborhood Hits	2
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

LAD1_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.022952 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MIRO1_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.015715 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXI2, Q6NUR3, Q6P9F8, Q6PJG1, Q6YMW8, Q86UB0, Q8IW28, Q8IXJ7, Q9H067, Q9H9N8, Q9NUZ2	Gene names	RHOT1, ARHT1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (hMiro-1) (Ras homolog gene family member T1) (Rac-GTP-binding protein-like protein).

B3GA2_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.015492 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P59270	Gene names	B3gat2, Glcats
Domain Architecture
Description	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 2) (Glucuronosyltransferase-S) (GlcAT-S) (UDP-glucuronosyltransferase-S) (GlcAT-D).

PPARD_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.006116 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

RPGF5_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.012078 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

Hits sorted by NC score

TR100_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	O75448, Q14143, Q9NNY5	Gene names	THRAP4, ARC100, DRIP100, KIAA0130, TRAP100
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 100 kDa component (Trap100) (Thyroid hormone receptor-associated protein 4) (Vitamin D3 receptor-interacting protein complex component DRIP100) (Activator- recruited cofactor 100 kDa component) (ARC100).

RHBD3_MOUSE
NC score	0.112084 (rank : 2)	θ value	0.365318 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP97, Q3U0Y4, Q5SUT5, Q5SUT6, Q5SUT7	Gene names	Rhbdd3
Domain Architecture	No domain graphic available
Description	Rhomboid domain-containing protein 3.

RHBD3_HUMAN
NC score	0.103731 (rank : 3)	θ value	0.813845 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3P4, Q6I9X3, Q9UGQ7	Gene names	RHBDD3, C22orf3
Domain Architecture
Description	Rhomboid domain-containing protein 3.

RT29_HUMAN
NC score	0.055468 (rank : 4)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P51398, Q13044, Q96Q20	Gene names	DAP3, MRPS29
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S29 (S29mt) (MRP-S29) (Death- associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein).

LAD1_HUMAN
NC score	0.022952 (rank : 5)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	441	Shared Neighborhood Hits	3
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

CO6A3_HUMAN
NC score	0.016654 (rank : 6)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

MIRO1_HUMAN
NC score	0.015715 (rank : 7)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXI2, Q6NUR3, Q6P9F8, Q6PJG1, Q6YMW8, Q86UB0, Q8IW28, Q8IXJ7, Q9H067, Q9H9N8, Q9NUZ2	Gene names	RHOT1, ARHT1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (hMiro-1) (Ras homolog gene family member T1) (Rac-GTP-binding protein-like protein).

B3GA2_MOUSE
NC score	0.015492 (rank : 8)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P59270	Gene names	B3gat2, Glcats
Domain Architecture
Description	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 2) (Glucuronosyltransferase-S) (GlcAT-S) (UDP-glucuronosyltransferase-S) (GlcAT-D).

RPGF5_HUMAN
NC score	0.012078 (rank : 9)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

BPAEA_HUMAN
NC score	0.008132 (rank : 10)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	1369	Shared Neighborhood Hits	2
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PPARD_HUMAN
NC score	0.006116 (rank : 11)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).