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Network neighborhood for query Sequence : TKT_HUMAN

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TKT_HUMAN
SwissProt Accessions	P29401, Q8TBA3, Q96HH3	Gene names	TKT
Domain Architecture
Description	Transketolase (EC 2.2.1.1) (TK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TKT2_HUMAN
θ value	0 (rank : 1)	NC score	0.984460 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P51854	Gene names	TKTL1, TKR, TKT2
Domain Architecture
Description	Transketolase-like 1 (EC 2.2.1.1) (Transketolase 2) (TK 2) (Transketolase-related protein).

TKT_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P29401, Q8TBA3, Q96HH3	Gene names	TKT
Domain Architecture
Description	Transketolase (EC 2.2.1.1) (TK).

TKT_MOUSE
θ value	0 (rank : 3)	NC score	0.999548 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P40142	Gene names	Tkt
Domain Architecture
Description	Transketolase (EC 2.2.1.1) (TK) (P68).

ODPB_HUMAN
θ value	2.88788e-06 (rank : 4)	NC score	0.326472 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P11177, Q6FH45, Q9BQ27, Q9UFK3	Gene names	PDHB, PHE1B
Domain Architecture
Description	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor (EC 1.2.4.1) (PDHE1-B).

ODPB_MOUSE
θ value	1.43324e-05 (rank : 5)	NC score	0.319356 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D051	Gene names	Pdhb
Domain Architecture
Description	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor (EC 1.2.4.1) (PDHE1-B).

ODBA_MOUSE
θ value	0.0563607 (rank : 6)	NC score	0.138152 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P50136	Gene names	Bckdha
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha).

ODBA_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.134468 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P12694, Q16034, Q16472	Gene names	BCKDHA
Domain Architecture
Description	2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A).

ODPA_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.102869 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P08559, Q9NP12, Q9UBJ8, Q9UBU0, Q9UNG4, Q9UNG5	Gene names	PDHA1, PHE1A
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type I).

ODPA_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.103118 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P35486	Gene names	Pdha1, Pdha-1
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type I).

ODPAT_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.086981 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P29803	Gene names	PDHA2
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

ODPAT_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.081830 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P35487	Gene names	Pdha2, Pdha-2, Pdhal
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

MYH10_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.006317 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1620	Shared Neighborhood Hits	5
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ODBB_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.119548 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P21953	Gene names	BCKDHB
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta).

Hits sorted by NC score

TKT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P29401, Q8TBA3, Q96HH3	Gene names	TKT
Domain Architecture
Description	Transketolase (EC 2.2.1.1) (TK).

TKT_MOUSE
NC score	0.999548 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P40142	Gene names	Tkt
Domain Architecture
Description	Transketolase (EC 2.2.1.1) (TK) (P68).

TKT2_HUMAN
NC score	0.984460 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P51854	Gene names	TKTL1, TKR, TKT2
Domain Architecture
Description	Transketolase-like 1 (EC 2.2.1.1) (Transketolase 2) (TK 2) (Transketolase-related protein).

ODPB_HUMAN
NC score	0.326472 (rank : 4)	θ value	2.88788e-06 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P11177, Q6FH45, Q9BQ27, Q9UFK3	Gene names	PDHB, PHE1B
Domain Architecture
Description	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor (EC 1.2.4.1) (PDHE1-B).

ODPB_MOUSE
NC score	0.319356 (rank : 5)	θ value	1.43324e-05 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D051	Gene names	Pdhb
Domain Architecture
Description	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor (EC 1.2.4.1) (PDHE1-B).

ODBA_MOUSE
NC score	0.138152 (rank : 6)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P50136	Gene names	Bckdha
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha).

ODBA_HUMAN
NC score	0.134468 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P12694, Q16034, Q16472	Gene names	BCKDHA
Domain Architecture
Description	2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A).

ODBB_HUMAN
NC score	0.119548 (rank : 8)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P21953	Gene names	BCKDHB
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta).

ODPA_MOUSE
NC score	0.103118 (rank : 9)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P35486	Gene names	Pdha1, Pdha-1
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type I).

ODPA_HUMAN
NC score	0.102869 (rank : 10)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P08559, Q9NP12, Q9UBJ8, Q9UBU0, Q9UNG4, Q9UNG5	Gene names	PDHA1, PHE1A
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type I).

ODPAT_HUMAN
NC score	0.086981 (rank : 11)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P29803	Gene names	PDHA2
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

ODPAT_MOUSE
NC score	0.081830 (rank : 12)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P35487	Gene names	Pdha2, Pdha-2, Pdhal
Domain Architecture
Description	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II).

MYH10_HUMAN
NC score	0.006317 (rank : 14)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	1620	Shared Neighborhood Hits	5
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).