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Network neighborhood for query Sequence : T53I2_HUMAN

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T53I2_HUMAN
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

T53I2_MOUSE
θ value	7.20884e-74 (rank : 1)	NC score	0.989433 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

T53I2_HUMAN
θ value	9.74306e-71 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

T53I1_HUMAN
θ value	4.15078e-21 (rank : 3)	NC score	0.804599 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A56, Q969R9	Gene names	TP53INP1, P53DINP1, SIP
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 1 (p53-dependent damage- inducible nuclear protein 1) (p53DINP1) (Stress-induced protein).

T53I1_MOUSE
θ value	9.24701e-21 (rank : 4)	NC score	0.808368 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXE4, Q923I6	Gene names	Trp53inp1, Sip
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 1 (p53-dependent damage- inducible nuclear protein 1) (p53DINP1) (Stress-induced protein) (Thymus-expressed acidic protein) (TEAP).

MILK1_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.040305 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RPOM_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.053600 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O00411, O60370	Gene names	POLRMT
Domain Architecture
Description	DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) (MtRPOL).

ZN750_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.035784 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	346	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

POLS2_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.008429 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

ERBB2_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.004734 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1073	Shared Neighborhood Hits	4
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

IRF3_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.018603 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	129	Shared Neighborhood Hits	2
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

RFIP3_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.021601 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	1055	Shared Neighborhood Hits	6
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CBL_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.017177 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CP007_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.024233 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

TLE2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.016238 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

CTND2_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.017600 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

DIDO1_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.017698 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MRCKB_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.000967 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	2239	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RGS3_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.009776 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	1621	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NEIL1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.017880 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

SYNJ2_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.012360 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

ZN409_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.008448 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

Hits sorted by NC score

T53I2_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.74306e-71 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

T53I2_MOUSE
NC score	0.989433 (rank : 2)	θ value	7.20884e-74 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

T53I1_MOUSE
NC score	0.808368 (rank : 3)	θ value	9.24701e-21 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXE4, Q923I6	Gene names	Trp53inp1, Sip
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 1 (p53-dependent damage- inducible nuclear protein 1) (p53DINP1) (Stress-induced protein) (Thymus-expressed acidic protein) (TEAP).

T53I1_HUMAN
NC score	0.804599 (rank : 4)	θ value	4.15078e-21 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A56, Q969R9	Gene names	TP53INP1, P53DINP1, SIP
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 1 (p53-dependent damage- inducible nuclear protein 1) (p53DINP1) (Stress-induced protein).

RPOM_HUMAN
NC score	0.053600 (rank : 5)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O00411, O60370	Gene names	POLRMT
Domain Architecture
Description	DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) (MtRPOL).

MILK1_MOUSE
NC score	0.040305 (rank : 6)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ZN750_MOUSE
NC score	0.035784 (rank : 7)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	346	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CP007_MOUSE
NC score	0.024233 (rank : 8)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

RFIP3_HUMAN
NC score	0.021601 (rank : 9)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	1055	Shared Neighborhood Hits	6
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

IRF3_HUMAN
NC score	0.018603 (rank : 10)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	129	Shared Neighborhood Hits	2
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

NEIL1_MOUSE
NC score	0.017880 (rank : 11)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

DIDO1_HUMAN
NC score	0.017698 (rank : 12)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CTND2_MOUSE
NC score	0.017600 (rank : 13)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CBL_MOUSE
NC score	0.017177 (rank : 14)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TLE2_MOUSE
NC score	0.016238 (rank : 15)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

SYNJ2_HUMAN
NC score	0.012360 (rank : 16)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

RGS3_MOUSE
NC score	0.009776 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1621	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZN409_HUMAN
NC score	0.008448 (rank : 18)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	842	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

POLS2_HUMAN
NC score	0.008429 (rank : 19)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

ERBB2_HUMAN
NC score	0.004734 (rank : 20)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	1073	Shared Neighborhood Hits	4
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MRCKB_HUMAN
NC score	0.000967 (rank : 21)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	2239	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).