Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : T23O_MOUSE

For an explanation of this page, click here

T23O_MOUSE
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

T23O_HUMAN
θ value	0 (rank : 1)	NC score	0.987731 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P48775	Gene names	TDO2, TDO
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

T23O_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

DBNL_MOUSE
θ value	0.47712 (rank : 3)	NC score	0.046922 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DZIP1_HUMAN
θ value	0.813845 (rank : 4)	NC score	0.044446 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	675	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

U2AFL_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.028756 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	503	Shared Neighborhood Hits	8
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

RBCC1_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.028268 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	1023	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

DYR1B_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.009188 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	799	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

NFL_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.014191 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	695	Shared Neighborhood Hits	12
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

DBNL_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.039989 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DYR1B_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.009161 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	831	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

HOOK2_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.022729 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	736	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

NFL_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.013769 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	666	Shared Neighborhood Hits	12
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

XE7_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.021464 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	738	Shared Neighborhood Hits	10
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BAZ1A_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.016564 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	693	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DIAP3_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.015397 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DZIP1_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.037363 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

HOOK1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.018393 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MACF1_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.009966 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

HOOK1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.017642 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	910	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

CK5P2_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.011431 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

NU205_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.019971 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

Hits sorted by NC score

T23O_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

T23O_HUMAN
NC score	0.987731 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P48775	Gene names	TDO2, TDO
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

DBNL_MOUSE
NC score	0.046922 (rank : 3)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DZIP1_HUMAN
NC score	0.044446 (rank : 4)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	675	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

DBNL_HUMAN
NC score	0.039989 (rank : 5)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DZIP1_MOUSE
NC score	0.037363 (rank : 6)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

U2AFL_HUMAN
NC score	0.028756 (rank : 7)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	503	Shared Neighborhood Hits	8
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

RBCC1_HUMAN
NC score	0.028268 (rank : 8)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	1023	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

HOOK2_MOUSE
NC score	0.022729 (rank : 9)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	736	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

XE7_HUMAN
NC score	0.021464 (rank : 10)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	738	Shared Neighborhood Hits	10
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

NU205_HUMAN
NC score	0.019971 (rank : 11)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

HOOK1_HUMAN
NC score	0.018393 (rank : 12)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
NC score	0.017642 (rank : 13)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	910	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

BAZ1A_HUMAN
NC score	0.016564 (rank : 14)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	693	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DIAP3_MOUSE
NC score	0.015397 (rank : 15)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

NFL_MOUSE
NC score	0.014191 (rank : 16)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	695	Shared Neighborhood Hits	12
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NFL_HUMAN
NC score	0.013769 (rank : 17)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	666	Shared Neighborhood Hits	12
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

CK5P2_MOUSE
NC score	0.011431 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MACF1_MOUSE
NC score	0.009966 (rank : 19)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

DYR1B_MOUSE
NC score	0.009188 (rank : 20)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	799	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

DYR1B_HUMAN
NC score	0.009161 (rank : 21)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	831	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).