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Network neighborhood for query Sequence : STAP1_HUMAN

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STAP1_HUMAN
SwissProt Accessions	Q9ULZ2	Gene names	STAP1, BRDG1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (BCR downstream signaling protein 1) (Docking protein BRDG1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STAP1_HUMAN
θ value	4.86655e-163 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULZ2	Gene names	STAP1, BRDG1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (BCR downstream signaling protein 1) (Docking protein BRDG1).

STAP1_MOUSE
θ value	1.12976e-135 (rank : 2)	NC score	0.989896 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JM90, Q3TRM1, Q6PES6	Gene names	Stap1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1).

STAP2_MOUSE
θ value	1.28434e-38 (rank : 3)	NC score	0.836040 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

STAP2_HUMAN
θ value	4.13158e-37 (rank : 4)	NC score	0.839431 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

DGKH_HUMAN
θ value	1.09739e-05 (rank : 5)	NC score	0.145315 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKD_HUMAN
θ value	0.00020696 (rank : 6)	NC score	0.134757 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

SRMS_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.012857 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	946	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

MYST3_HUMAN
θ value	0.125558 (rank : 8)	NC score	0.029173 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	772	Shared Neighborhood Hits	6
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PLCG2_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.051836 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

TIAM1_MOUSE
θ value	0.365318 (rank : 10)	NC score	0.062032 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TOM1_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.034666 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TIAM1_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.058084 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TTC1_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.035549 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

FINC_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.021279 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LAMA2_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.008940 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	1198	Shared Neighborhood Hits	5
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FGD5_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.020020 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

GOGB1_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.007218 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	2297	Shared Neighborhood Hits	8
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TTC1_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.030128 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ANK2_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.006216 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1615	Shared Neighborhood Hits	3
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

FINC_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.018930 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

NKX61_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.005718 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

FGD6_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.013975 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

DGKK_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.060840 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	378	Shared Neighborhood Hits	3
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

Hits sorted by NC score

STAP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.86655e-163 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULZ2	Gene names	STAP1, BRDG1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (BCR downstream signaling protein 1) (Docking protein BRDG1).

STAP1_MOUSE
NC score	0.989896 (rank : 2)	θ value	1.12976e-135 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JM90, Q3TRM1, Q6PES6	Gene names	Stap1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1).

STAP2_HUMAN
NC score	0.839431 (rank : 3)	θ value	4.13158e-37 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

STAP2_MOUSE
NC score	0.836040 (rank : 4)	θ value	1.28434e-38 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

DGKH_HUMAN
NC score	0.145315 (rank : 5)	θ value	1.09739e-05 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKD_HUMAN
NC score	0.134757 (rank : 6)	θ value	0.00020696 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

TIAM1_MOUSE
NC score	0.062032 (rank : 7)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

DGKK_HUMAN
NC score	0.060840 (rank : 8)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	378	Shared Neighborhood Hits	3
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TIAM1_HUMAN
NC score	0.058084 (rank : 9)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PLCG2_HUMAN
NC score	0.051836 (rank : 10)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

TTC1_MOUSE
NC score	0.035549 (rank : 11)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TOM1_HUMAN
NC score	0.034666 (rank : 12)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TTC1_HUMAN
NC score	0.030128 (rank : 13)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

MYST3_HUMAN
NC score	0.029173 (rank : 14)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	772	Shared Neighborhood Hits	6
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

FINC_MOUSE
NC score	0.021279 (rank : 15)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FGD5_MOUSE
NC score	0.020020 (rank : 16)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FINC_HUMAN
NC score	0.018930 (rank : 17)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FGD6_HUMAN
NC score	0.013975 (rank : 18)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

SRMS_HUMAN
NC score	0.012857 (rank : 19)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	946	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

LAMA2_MOUSE
NC score	0.008940 (rank : 20)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	1198	Shared Neighborhood Hits	5
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

GOGB1_HUMAN
NC score	0.007218 (rank : 21)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	2297	Shared Neighborhood Hits	8
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ANK2_HUMAN
NC score	0.006216 (rank : 22)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	1615	Shared Neighborhood Hits	3
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

NKX61_MOUSE
NC score	0.005718 (rank : 23)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.