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Network neighborhood for query Sequence : STAG1_HUMAN

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STAG1_HUMAN
SwissProt Accessions	Q8WVM7, O00539	Gene names	STAG1, SA1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STAG1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WVM7, O00539	Gene names	STAG1, SA1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

STAG1_MOUSE
θ value	0 (rank : 2)	NC score	0.999348 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D3E6, O08982	Gene names	Stag1, Sa1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

STAG2_HUMAN
θ value	0 (rank : 3)	NC score	0.993341 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3U4, O00540, Q5JTI6, Q9H1N8	Gene names	STAG2, SA2
Domain Architecture
Description	Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2).

STAG2_MOUSE
θ value	0 (rank : 4)	NC score	0.993372 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	O35638, Q6NZN7	Gene names	Stag2, Sa2, Sap2
Domain Architecture
Description	Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2).

STAG3_HUMAN
θ value	0 (rank : 5)	NC score	0.982565 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

STAG3_MOUSE
θ value	0 (rank : 6)	NC score	0.982568 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

FANCM_MOUSE
θ value	0.0330416 (rank : 7)	NC score	0.053707 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

CJ068_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.072606 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

PK3CG_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.028345 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	0.365318 (rank : 10)	NC score	0.028338 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

TPR_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.009691 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	1921	Shared Neighborhood Hits	14
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MYT1L_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.026037 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

ROCK2_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.006931 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	2073	Shared Neighborhood Hits	14
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CTRO_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.007848 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	2092	Shared Neighborhood Hits	14
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYO5C_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.009210 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	1206	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ACE2_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.022596 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

CTRO_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.006943 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	2344	Shared Neighborhood Hits	14
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DUS3L_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.016555 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

GCYB2_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.014157 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

MICA2_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.012970 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

SAS10_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.064738 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

ANKS1_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.006927 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CCD46_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.012336 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	1430	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

NOL8_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.018218 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

ADAM9_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.005395 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

CI041_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.020492 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UY1, Q9CWF3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf41 homolog.

IFIH1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.016820 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LETM1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.019366 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

RGP1_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.017239 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SAS10_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.043527 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

SPT19_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.029457 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAQ9, Q810M9	Gene names	Spata19, Spergen1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 19, mitochondrial precursor (Spermatogenic cell-specific gene 1) (Spergen-1).

CI041_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.018189 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4J0, Q7Z383, Q8N7C5	Gene names	C9orf41
Domain Architecture	No domain graphic available
Description	Protein C9orf41.

EZRI_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.007117 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	693	Shared Neighborhood Hits	11
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

NCKX2_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.022755 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

PRP40_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.013896 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

ROCK2_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.003850 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	2072	Shared Neighborhood Hits	13
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

UBP37_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.009236 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

ZFP13_MOUSE
θ value	6.88961 (rank : 38)	NC score	-0.001580 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	771	Shared Neighborhood Hits	2
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

DBP_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.006258 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

MEFV_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.002173 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PAK4_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.000169 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PRP40_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.012403 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RAD54_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.005977 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

Hits sorted by NC score

STAG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WVM7, O00539	Gene names	STAG1, SA1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

STAG1_MOUSE
NC score	0.999348 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D3E6, O08982	Gene names	Stag1, Sa1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

STAG2_MOUSE
NC score	0.993372 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	O35638, Q6NZN7	Gene names	Stag2, Sa2, Sap2
Domain Architecture
Description	Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2).

STAG2_HUMAN
NC score	0.993341 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3U4, O00540, Q5JTI6, Q9H1N8	Gene names	STAG2, SA2
Domain Architecture
Description	Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2).

STAG3_MOUSE
NC score	0.982568 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

STAG3_HUMAN
NC score	0.982565 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

CJ068_HUMAN
NC score	0.072606 (rank : 7)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

SAS10_MOUSE
NC score	0.064738 (rank : 8)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

FANCM_MOUSE
NC score	0.053707 (rank : 9)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

SAS10_HUMAN
NC score	0.043527 (rank : 10)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

SPT19_MOUSE
NC score	0.029457 (rank : 11)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAQ9, Q810M9	Gene names	Spata19, Spergen1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 19, mitochondrial precursor (Spermatogenic cell-specific gene 1) (Spergen-1).

PK3CG_HUMAN
NC score	0.028345 (rank : 12)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.028338 (rank : 13)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

MYT1L_HUMAN
NC score	0.026037 (rank : 14)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NCKX2_HUMAN
NC score	0.022755 (rank : 15)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

ACE2_HUMAN
NC score	0.022596 (rank : 16)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

CI041_MOUSE
NC score	0.020492 (rank : 17)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UY1, Q9CWF3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf41 homolog.

LETM1_HUMAN
NC score	0.019366 (rank : 18)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

NOL8_MOUSE
NC score	0.018218 (rank : 19)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

CI041_HUMAN
NC score	0.018189 (rank : 20)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4J0, Q7Z383, Q8N7C5	Gene names	C9orf41
Domain Architecture	No domain graphic available
Description	Protein C9orf41.

RGP1_MOUSE
NC score	0.017239 (rank : 21)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

IFIH1_HUMAN
NC score	0.016820 (rank : 22)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

DUS3L_HUMAN
NC score	0.016555 (rank : 23)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

GCYB2_HUMAN
NC score	0.014157 (rank : 24)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

PRP40_MOUSE
NC score	0.013896 (rank : 25)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

MICA2_HUMAN
NC score	0.012970 (rank : 26)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

PRP40_HUMAN
NC score	0.012403 (rank : 27)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CCD46_HUMAN
NC score	0.012336 (rank : 28)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	1430	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TPR_HUMAN
NC score	0.009691 (rank : 29)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	1921	Shared Neighborhood Hits	14
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UBP37_HUMAN
NC score	0.009236 (rank : 30)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

MYO5C_HUMAN
NC score	0.009210 (rank : 31)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	1206	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CTRO_HUMAN
NC score	0.007848 (rank : 32)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	2092	Shared Neighborhood Hits	14
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EZRI_MOUSE
NC score	0.007117 (rank : 33)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	693	Shared Neighborhood Hits	11
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CTRO_MOUSE
NC score	0.006943 (rank : 34)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	2344	Shared Neighborhood Hits	14
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ROCK2_HUMAN
NC score	0.006931 (rank : 35)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	2073	Shared Neighborhood Hits	14
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ANKS1_HUMAN
NC score	0.006927 (rank : 36)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

DBP_HUMAN
NC score	0.006258 (rank : 37)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

RAD54_MOUSE
NC score	0.005977 (rank : 38)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

ADAM9_MOUSE
NC score	0.005395 (rank : 39)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ROCK2_MOUSE
NC score	0.003850 (rank : 40)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	2072	Shared Neighborhood Hits	13
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

MEFV_HUMAN
NC score	0.002173 (rank : 41)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PAK4_MOUSE
NC score	0.000169 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ZFP13_MOUSE
NC score	-0.001580 (rank : 43)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	771	Shared Neighborhood Hits	2
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).