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Network neighborhood for query Sequence : SPB5_HUMAN

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SPB5_HUMAN
SwissProt Accessions	P36952	Gene names	SERPINB5, PI5
Domain Architecture
Description	Serpin B5 precursor (Maspin) (Protease inhibitor 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPB5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	P36952	Gene names	SERPINB5, PI5
Domain Architecture
Description	Serpin B5 precursor (Maspin) (Protease inhibitor 5).

SPB5_MOUSE
θ value	0 (rank : 2)	NC score	0.999097 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	82
SwissProt Accessions	P70124	Gene names	Serpinb5, Pi5, Spi5, Spi7
Domain Architecture
Description	Serpin B5 precursor (Maspin) (Protease inhibitor 5).

ILEU_HUMAN
θ value	1.40038e-85 (rank : 3)	NC score	0.992495 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P30740, Q53FB9, Q5W0E1	Gene names	SERPINB1, ELANH2, PI2
Domain Architecture
Description	Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).

SPB10_MOUSE
θ value	1.96316e-71 (rank : 4)	NC score	0.988383 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1K6	Gene names	Serpinb10
Domain Architecture	No domain graphic available
Description	Serpin B10.

SPB9_HUMAN
θ value	3.34864e-71 (rank : 5)	NC score	0.988393 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P50453	Gene names	SERPINB9, PI9
Domain Architecture
Description	Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Protease inhibitor 9).

SPB8_MOUSE
θ value	5.71191e-71 (rank : 6)	NC score	0.987559 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

SPB3_HUMAN
θ value	1.66191e-70 (rank : 7)	NC score	0.985649 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	P29508, Q96J21	Gene names	SERPINB3, SCCA, SCCA1
Domain Architecture
Description	Serpin B3 (Squamous cell carcinoma antigen 1) (SCCA-1) (Protein T4-A).

SPB10_HUMAN
θ value	6.98233e-69 (rank : 8)	NC score	0.988971 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P48595, Q4VAX4	Gene names	SERPINB10, PI10
Domain Architecture
Description	Serpin B10 (Bomapin) (Protease inhibitor 10).

SPB6_HUMAN
θ value	1.19101e-68 (rank : 9)	NC score	0.988034 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P35237, Q96J44	Gene names	SERPINB6, PI6, PTI
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiproteinase) (CAP) (Protease inhibitor 6) (PI-6).

SPB8_HUMAN
θ value	1.31681e-67 (rank : 10)	NC score	0.987554 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	P50452	Gene names	SERPINB8, PI8
Domain Architecture
Description	Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Protease inhibitor 8).

SPB4_HUMAN
θ value	2.24614e-67 (rank : 11)	NC score	0.984994 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P48594	Gene names	SERPINB4, SCCA2
Domain Architecture
Description	Serpin B4 (Squamous cell carcinoma antigen 2) (SCCA-2) (Leupin).

SPB6_MOUSE
θ value	3.24342e-66 (rank : 12)	NC score	0.987621 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q60854	Gene names	Serpinb6, Serpinb6a, Spi3
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Protease inhibitor 6) (PI- 6).

SPB12_HUMAN
θ value	6.11685e-65 (rank : 13)	NC score	0.988072 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P63	Gene names	SERPINB12
Domain Architecture
Description	Serpin B12.

SPB13_HUMAN
θ value	1.04338e-64 (rank : 14)	NC score	0.983957 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIV8, Q9HCX1, Q9UBW1, Q9UKG0	Gene names	SERPINB13, PI13
Domain Architecture
Description	Serpin B13 (Hurpin) (HaCaT UV-repressible serpin) (Protease inhibitor 13) (Headpin).

PAI2_HUMAN
θ value	7.47731e-63 (rank : 15)	NC score	0.986836 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P05120, Q96E96	Gene names	SERPINB2, PAI2, PLANH2
Domain Architecture
Description	Plasminogen activator inhibitor 2 precursor (PAI-2) (Placental plasminogen activator inhibitor) (Monocyte Arg-serpin) (Urokinase inhibitor).

SPB13_MOUSE
θ value	9.76566e-63 (rank : 16)	NC score	0.985823 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CDC0	Gene names	Serpinb13
Domain Architecture	No domain graphic available
Description	Serpin B13.

SPB11_HUMAN
θ value	1.84173e-61 (rank : 17)	NC score	0.987629 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P15, Q96P13, Q96P14	Gene names	SERPINB11
Domain Architecture
Description	Serpin B11.

PAI2_MOUSE
θ value	6.99855e-61 (rank : 18)	NC score	0.986483 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P12388, O35687, Q9QWP6, Q9QWP7, Q9QWP8, Q9QWP9, Q9QWQ0, Q9QWZ5, Q9QWZ6	Gene names	Serpinb2, Pai2, Planh2
Domain Architecture
Description	Plasminogen activator inhibitor 2, macrophage (PAI-2).

SPB7_HUMAN
θ value	1.11734e-58 (rank : 19)	NC score	0.986041 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	O75635, Q3KPG4	Gene names	SERPINB7
Domain Architecture
Description	Serpin B7 (Megsin) (TP55).

SPB12_MOUSE
θ value	5.54529e-58 (rank : 20)	NC score	0.985411 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

SPB11_MOUSE
θ value	2.32979e-56 (rank : 21)	NC score	0.987426 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQV3, Q91Z12	Gene names	Serpinb11
Domain Architecture	No domain graphic available
Description	Serpin B11.

SPB7_MOUSE
θ value	1.66964e-54 (rank : 22)	NC score	0.985541 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D695	Gene names	Serpinb7
Domain Architecture
Description	Serpin B7 (Megsin).

SPI2_MOUSE
θ value	2.67181e-44 (rank : 23)	NC score	0.974019 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JK88, Q9D8Z3, Q9D955	Gene names	Serpini2, Spi14
Domain Architecture
Description	Serpin I2 precursor (Serine protease inhibitor 14).

SPI2_HUMAN
θ value	5.03882e-43 (rank : 24)	NC score	0.973207 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	O75830	Gene names	SERPINI2, MEPI, PI14
Domain Architecture
Description	Serpin I2 precursor (Myoepithelium-derived serine protease inhibitor) (Pancpin) (Protease inhibitor 14) (TSA2004).

ANT3_MOUSE
θ value	8.59492e-43 (rank : 25)	NC score	0.976070 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P32261	Gene names	Serpinc1, At3
Domain Architecture
Description	Antithrombin-III precursor (ATIII).

SPA3C_MOUSE
θ value	7.27602e-42 (rank : 26)	NC score	0.944242 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P29621	Gene names	Serpina3c, Klkbp
Domain Architecture
Description	Serine protease inhibitor A3C precursor (Kallikrein-binding protein) (KBP) (Serpin A3C).

SPA3K_MOUSE
θ value	1.05066e-40 (rank : 27)	NC score	0.940948 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P07759, Q91W80, Q91X80	Gene names	Serpina3k, Mcm2, Spi2
Domain Architecture
Description	Serine protease inhibitor A3K precursor (Contrapsin) (Serpin A3K).

THBG_HUMAN
θ value	3.05695e-40 (rank : 28)	NC score	0.942808 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P05543	Gene names	SERPINA7, TBG
Domain Architecture
Description	Thyroxine-binding globulin precursor (T4-binding globulin) (Serpin A7).

ANT3_HUMAN
θ value	5.21438e-40 (rank : 29)	NC score	0.975082 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P01008, P78439, P78447, Q13815, Q7KZ43	Gene names	SERPINC1, AT3
Domain Architecture
Description	Antithrombin-III precursor (ATIII).

SPA3M_MOUSE
θ value	6.81017e-40 (rank : 30)	NC score	0.939950 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	Q03734, Q62260	Gene names	Serpina3m
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3M precursor (Serpin A3M).

NEUS_MOUSE
θ value	1.98146e-39 (rank : 31)	NC score	0.968251 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	O35684, Q543F7, Q922U6	Gene names	Serpini1, Pi12, Spi17
Domain Architecture
Description	Neuroserpin precursor (Serpin I1) (Protease inhibitor 17).

SPA9_MOUSE
θ value	7.52953e-39 (rank : 32)	NC score	0.950555 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D7D2	Gene names	Serpina9
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor.

HEP2_MOUSE
θ value	9.83387e-39 (rank : 33)	NC score	0.964434 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P49182	Gene names	Serpind1, Hcf2, Hcii
Domain Architecture
Description	Heparin cofactor 2 precursor (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin 2).

NEUS_HUMAN
θ value	9.83387e-39 (rank : 34)	NC score	0.970298 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q99574, Q6AHZ4	Gene names	SERPINI1, PI12
Domain Architecture
Description	Neuroserpin precursor (Serpin I1) (Protease inhibitor 12).

SPA3F_MOUSE
θ value	2.86122e-38 (rank : 35)	NC score	0.938260 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	Q80X76	Gene names	Serpina3f
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3F (Serpin A3F).

HEP2_HUMAN
θ value	4.88048e-38 (rank : 36)	NC score	0.963560 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P05546, Q6IBZ5	Gene names	SERPIND1, HCF2
Domain Architecture
Description	Heparin cofactor 2 precursor (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin 2) (HLS2).

AACT_HUMAN
θ value	1.85459e-37 (rank : 37)	NC score	0.946067 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P01011, Q13703, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UNU9	Gene names	SERPINA3, AACT
Domain Architecture
Description	Alpha-1-antichymotrypsin precursor (ACT) [Contains: Alpha-1- antichymotrypsin His-Pro-less].

SERPH_HUMAN
θ value	3.16345e-37 (rank : 38)	NC score	0.963850 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P50454, P29043, Q5XPB4, Q6NSJ6, Q8IY96, Q9NP88	Gene names	SERPINH1, CBP1, CBP2, HSP47, PIG14, SERPINH2
Domain Architecture
Description	Serpin H1 precursor (Collagen-binding protein) (Colligin) (47 kDa heat shock protein) (Rheumatoid arthritis-related antigen RA-A47) (Arsenic- transactivated protein 3) (AsTP3) (Proliferation-inducing gene 14 protein).

SPA12_MOUSE
θ value	4.13158e-37 (rank : 39)	NC score	0.952256 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TMF5, Q9CQ32	Gene names	Serpina12
Domain Architecture	No domain graphic available
Description	Serpin A12 precursor (Visceral adipose-specific serpin) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin).

SPA3N_MOUSE
θ value	1.20211e-36 (rank : 40)	NC score	0.937542 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).

SPA12_HUMAN
θ value	1.57e-36 (rank : 41)	NC score	0.946089 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IW75	Gene names	SERPINA12
Domain Architecture	No domain graphic available
Description	Serpin A12 precursor (Visceral adipose-specific serpin) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (OL-64).

PAI1_MOUSE
θ value	2.05049e-36 (rank : 42)	NC score	0.966673 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	77	Shared Neighborhood Hits	75
SwissProt Accessions	P22777	Gene names	Serpine1, Mr1, Pai1, Planh1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

SPA9_HUMAN
θ value	2.05049e-36 (rank : 43)	NC score	0.945290 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86WD7, Q6UWP9, Q86WD6, Q86YP6, Q86YP7	Gene names	SERPINA9, GCET1, SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor (Germinal center B-cell expressed transcript 1 protein).

SERPH_MOUSE
θ value	2.67802e-36 (rank : 44)	NC score	0.963725 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P19324	Gene names	Serpinh1, Cbp1, Hsp47
Domain Architecture
Description	Serpin H1 precursor (Collagen-binding protein) (Colligin) (47 kDa heat shock protein) (Serine protease inhibitor J6).

PAI1_HUMAN
θ value	3.4976e-36 (rank : 45)	NC score	0.962502 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P05121	Gene names	SERPINE1, PAI1, PLANH1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

SPA3G_MOUSE
θ value	2.96089e-35 (rank : 46)	NC score	0.936371 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q5I2A0, Q6PG99	Gene names	Serpina3g, Spi2A
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3G (Serine protease inhibitor 2A) (Serpin A3G) (Serpin 2A).

GDN_MOUSE
θ value	5.0505e-35 (rank : 47)	NC score	0.964999 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	Q07235, Q921T7	Gene names	Serpine2, Pi7, Pn1, Spi4
Domain Architecture
Description	Glia-derived nexin precursor (GDN) (Protease nexin I) (PN-1) (Serine protease-inhibitor 4).

A1AT_HUMAN
θ value	8.61488e-35 (rank : 48)	NC score	0.940137 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P01009, Q13672, Q5U0M1, Q96BF9, Q96ES1, Q9P1P0	Gene names	SERPINA1, AAT, PI
Domain Architecture
Description	Alpha-1-antitrypsin precursor (Alpha-1 protease inhibitor) (Alpha-1- antiproteinase).

THBG_MOUSE
θ value	5.584e-34 (rank : 49)	NC score	0.942196 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P61939	Gene names	Serpina7, Tbg
Domain Architecture	No domain graphic available
Description	Thyroxine-binding globulin precursor (T4-binding globulin) (Serpin A7).

IPSP_HUMAN
θ value	9.52487e-34 (rank : 50)	NC score	0.947944 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P05154, Q07616, Q9UG30	Gene names	SERPINA5, PCI, PLANH3, PROCI
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Acrosomal serine protease inhibitor).

A1AT4_MOUSE
θ value	1.24399e-33 (rank : 51)	NC score	0.936358 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	75
SwissProt Accessions	Q00897	Gene names	Serpina1d, Dom4, Spi1-4
Domain Architecture
Description	Alpha-1-antitrypsin 1-4 precursor (Serine protease inhibitor 1-4) (Alpha-1 protease inhibitor 4).

A1AT2_MOUSE
θ value	1.6247e-33 (rank : 52)	NC score	0.931846 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	P22599, Q61283, Q80ZH5, Q8VC20	Gene names	Serpina1b, Aat2, Dom2, Spi1-2
Domain Architecture
Description	Alpha-1-antitrypsin 1-2 precursor (Serine protease inhibitor 1-2) (Alpha-1 protease inhibitor 2) (Alpha-1-antiproteinase) (AAT).

A1AT1_MOUSE
θ value	3.61944e-33 (rank : 53)	NC score	0.934872 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	P07758, Q80YB8, Q8JZV6, Q91XB8	Gene names	Serpina1a, Dom1, Spi1-1
Domain Architecture
Description	Alpha-1-antitrypsin 1-1 precursor (Serine protease inhibitor 1-1) (Alpha-1 protease inhibitor 1) (Alpha-1-antiproteinase) (AAT).

SPA3B_MOUSE
θ value	3.61944e-33 (rank : 54)	NC score	0.939362 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BYY9	Gene names	Serpina3b
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3B precursor (Serpin A3B).

A1AT6_MOUSE
θ value	1.0531e-32 (rank : 55)	NC score	0.930732 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P81105, Q91V74, Q91WH5, Q91XC1	Gene names	Spi1-6, Dom6
Domain Architecture	No domain graphic available
Description	Alpha-1-antitrypsin 1-6 precursor (Serine protease inhibitor 1-6) (Alpha-1 protease inhibitor 6).

A1AT5_MOUSE
θ value	8.91499e-32 (rank : 56)	NC score	0.933873 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q00898	Gene names	Serpina1e, Dom5, Spi1-5
Domain Architecture
Description	Alpha-1-antitrypsin 1-5 precursor (Serine protease inhibitor 1-5) (Alpha-1 protease inhibitor 5).

A1AT3_MOUSE
θ value	1.16434e-31 (rank : 57)	NC score	0.930205 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q00896	Gene names	Serpina1c, Dom3, Spi1-3
Domain Architecture
Description	Alpha-1-antitrypsin 1-3 precursor (Serine protease inhibitor 1-3) (Alpha-1 protease inhibitor 3).

SPA3A_MOUSE
θ value	1.52067e-31 (rank : 58)	NC score	0.933955 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

IPSP_MOUSE
θ value	1.98606e-31 (rank : 59)	NC score	0.940395 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P70458	Gene names	Serpina5, Pci
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3).

GDN_HUMAN
θ value	3.3877e-31 (rank : 60)	NC score	0.964380 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	P07093	Gene names	SERPINE2, PI7, PN1
Domain Architecture
Description	Glia-derived nexin precursor (GDN) (Protease nexin I) (PN-1) (Protease inhibitor 7).

CBG_HUMAN
θ value	2.05525e-28 (rank : 61)	NC score	0.942391 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P08185, Q7Z2Q9	Gene names	SERPINA6, CBG
Domain Architecture
Description	Corticosteroid-binding globulin precursor (CBG) (Transcortin) (Serpin A6).

SPA11_MOUSE
θ value	5.97985e-28 (rank : 62)	NC score	0.932115 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CIE0	Gene names	Serpina11
Domain Architecture	No domain graphic available
Description	Serpin A11 precursor.

ZPI_MOUSE
θ value	7.80994e-28 (rank : 63)	NC score	0.949856 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R121, Q8VCV8	Gene names	Serpina10, Zpi
Domain Architecture	No domain graphic available
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

PEDF_HUMAN
θ value	1.73987e-27 (rank : 64)	NC score	0.930131 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P36955, Q13236, Q96CT1, Q96R01, Q9BWA4	Gene names	SERPINF1, PEDF
Domain Architecture
Description	Pigment epithelium-derived factor precursor (PEDF) (Serpin-F1) (EPC- 1).

PEDF_MOUSE
θ value	3.87602e-27 (rank : 65)	NC score	0.934180 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P97298, O70629, O88691	Gene names	Serpinf1, Pedf, Sdf3
Domain Architecture
Description	Pigment epithelium-derived factor precursor (PEDF) (Serpin-F1) (Stromal cell-derived factor 3) (SDF-3) (Caspin).

CBG_MOUSE
θ value	1.47289e-26 (rank : 66)	NC score	0.930479 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q06770	Gene names	Serpina6, Cbg
Domain Architecture
Description	Corticosteroid-binding globulin precursor (CBG) (Transcortin) (Serpin A6).

A2AP_HUMAN
θ value	3.28125e-26 (rank : 67)	NC score	0.941274 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P08697	Gene names	SERPINF2, AAP, PLI
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

SPA11_HUMAN
θ value	7.30988e-26 (rank : 68)	NC score	0.934954 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q86U17	Gene names	SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A11 precursor.

A2AP_MOUSE
θ value	2.12685e-25 (rank : 69)	NC score	0.939566 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q61247	Gene names	Serpinf2, Pli
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

KAIN_HUMAN
θ value	5.23862e-24 (rank : 70)	NC score	0.933395 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P29622, Q53XB5, Q86TR9, Q96BZ5	Gene names	SERPINA4, KST, PI4
Domain Architecture
Description	Kallistatin precursor (Serpin A4) (Kallikrein inhibitor) (Protease inhibitor 4).

ZPI_HUMAN
θ value	6.84181e-24 (rank : 71)	NC score	0.946205 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK55, Q6UWX9, Q86U20	Gene names	SERPINA10, ZPI
Domain Architecture
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

A1ATR_HUMAN
θ value	1.2077e-20 (rank : 72)	NC score	0.921945 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P20848	Gene names	SERPINA2, ARGS, ATR, PIL
Domain Architecture
Description	Alpha-1-antitrypsin-related protein precursor.

IC1_HUMAN
θ value	1.42992e-13 (rank : 73)	NC score	0.915414 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	99	Shared Neighborhood Hits	75
SwissProt Accessions	P05155, Q547W3, Q59EI5, Q96FE0	Gene names	SERPING1, C1IN, C1NH
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

IC1_MOUSE
θ value	1.9326e-10 (rank : 74)	NC score	0.904048 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	164	Shared Neighborhood Hits	76
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

SPA13_HUMAN
θ value	1.43324e-05 (rank : 75)	NC score	0.837175 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXR4	Gene names	SERPINA13
Domain Architecture	No domain graphic available
Description	Serpin A13 precursor.

GOGA4_HUMAN
θ value	0.0193708 (rank : 76)	NC score	-0.001005 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	2034	Shared Neighborhood Hits	11
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RBCC1_MOUSE
θ value	0.47712 (rank : 77)	NC score	0.005328 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	1048	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

LIPB1_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.002694 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	640	Shared Neighborhood Hits	10
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

MAP9_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.006788 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MRCKA_HUMAN
θ value	1.81305 (rank : 80)	NC score	-0.006224 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	1999	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

P210L_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.012583 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

ANR26_HUMAN
θ value	2.36792 (rank : 82)	NC score	-0.003318 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	1614	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

LIMK2_HUMAN
θ value	2.36792 (rank : 83)	NC score	-0.006544 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	986	Shared Neighborhood Hits	6
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

SMC4_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.001002 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	830	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

LIMK2_MOUSE
θ value	3.0926 (rank : 85)	NC score	-0.006652 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	998	Shared Neighborhood Hits	6
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MRCKB_HUMAN
θ value	3.0926 (rank : 86)	NC score	-0.007475 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	2239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RBCC1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.001906 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	1023	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CDCP1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.005999 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

HECD1_HUMAN
θ value	8.99809 (rank : 89)	NC score	-0.002122 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	371	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

IL18_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.010518 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q14116, O75599	Gene names	IL18, IGIF, IL1F4
Domain Architecture
Description	Interleukin-18 precursor (IL-18) (Interferon-gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma) (Iboctadekin).

MRCKB_MOUSE
θ value	8.99809 (rank : 91)	NC score	-0.006893 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	2180	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ANGT_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.733388 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P01019, Q16358, Q16359, Q96F91	Gene names	AGT, SERPINA8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

ANGT_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.685074 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	P11859	Gene names	Agt, Serpina8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

Hits sorted by NC score

SPB5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	P36952	Gene names	SERPINB5, PI5
Domain Architecture
Description	Serpin B5 precursor (Maspin) (Protease inhibitor 5).

SPB5_MOUSE
NC score	0.999097 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	82
SwissProt Accessions	P70124	Gene names	Serpinb5, Pi5, Spi5, Spi7
Domain Architecture
Description	Serpin B5 precursor (Maspin) (Protease inhibitor 5).

ILEU_HUMAN
NC score	0.992495 (rank : 3)	θ value	1.40038e-85 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P30740, Q53FB9, Q5W0E1	Gene names	SERPINB1, ELANH2, PI2
Domain Architecture
Description	Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).

SPB10_HUMAN
NC score	0.988971 (rank : 4)	θ value	6.98233e-69 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P48595, Q4VAX4	Gene names	SERPINB10, PI10
Domain Architecture
Description	Serpin B10 (Bomapin) (Protease inhibitor 10).

SPB9_HUMAN
NC score	0.988393 (rank : 5)	θ value	3.34864e-71 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P50453	Gene names	SERPINB9, PI9
Domain Architecture
Description	Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Protease inhibitor 9).

SPB10_MOUSE
NC score	0.988383 (rank : 6)	θ value	1.96316e-71 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1K6	Gene names	Serpinb10
Domain Architecture	No domain graphic available
Description	Serpin B10.

SPB12_HUMAN
NC score	0.988072 (rank : 7)	θ value	6.11685e-65 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P63	Gene names	SERPINB12
Domain Architecture
Description	Serpin B12.

SPB6_HUMAN
NC score	0.988034 (rank : 8)	θ value	1.19101e-68 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P35237, Q96J44	Gene names	SERPINB6, PI6, PTI
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiproteinase) (CAP) (Protease inhibitor 6) (PI-6).

SPB11_HUMAN
NC score	0.987629 (rank : 9)	θ value	1.84173e-61 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P15, Q96P13, Q96P14	Gene names	SERPINB11
Domain Architecture
Description	Serpin B11.

SPB6_MOUSE
NC score	0.987621 (rank : 10)	θ value	3.24342e-66 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q60854	Gene names	Serpinb6, Serpinb6a, Spi3
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Protease inhibitor 6) (PI- 6).

SPB8_MOUSE
NC score	0.987559 (rank : 11)	θ value	5.71191e-71 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

SPB8_HUMAN
NC score	0.987554 (rank : 12)	θ value	1.31681e-67 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	P50452	Gene names	SERPINB8, PI8
Domain Architecture
Description	Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Protease inhibitor 8).

SPB11_MOUSE
NC score	0.987426 (rank : 13)	θ value	2.32979e-56 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQV3, Q91Z12	Gene names	Serpinb11
Domain Architecture	No domain graphic available
Description	Serpin B11.

PAI2_HUMAN
NC score	0.986836 (rank : 14)	θ value	7.47731e-63 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P05120, Q96E96	Gene names	SERPINB2, PAI2, PLANH2
Domain Architecture
Description	Plasminogen activator inhibitor 2 precursor (PAI-2) (Placental plasminogen activator inhibitor) (Monocyte Arg-serpin) (Urokinase inhibitor).

PAI2_MOUSE
NC score	0.986483 (rank : 15)	θ value	6.99855e-61 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P12388, O35687, Q9QWP6, Q9QWP7, Q9QWP8, Q9QWP9, Q9QWQ0, Q9QWZ5, Q9QWZ6	Gene names	Serpinb2, Pai2, Planh2
Domain Architecture
Description	Plasminogen activator inhibitor 2, macrophage (PAI-2).

SPB7_HUMAN
NC score	0.986041 (rank : 16)	θ value	1.11734e-58 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	O75635, Q3KPG4	Gene names	SERPINB7
Domain Architecture
Description	Serpin B7 (Megsin) (TP55).

SPB13_MOUSE
NC score	0.985823 (rank : 17)	θ value	9.76566e-63 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CDC0	Gene names	Serpinb13
Domain Architecture	No domain graphic available
Description	Serpin B13.

SPB3_HUMAN
NC score	0.985649 (rank : 18)	θ value	1.66191e-70 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	P29508, Q96J21	Gene names	SERPINB3, SCCA, SCCA1
Domain Architecture
Description	Serpin B3 (Squamous cell carcinoma antigen 1) (SCCA-1) (Protein T4-A).

SPB7_MOUSE
NC score	0.985541 (rank : 19)	θ value	1.66964e-54 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D695	Gene names	Serpinb7
Domain Architecture
Description	Serpin B7 (Megsin).

SPB12_MOUSE
NC score	0.985411 (rank : 20)	θ value	5.54529e-58 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

SPB4_HUMAN
NC score	0.984994 (rank : 21)	θ value	2.24614e-67 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P48594	Gene names	SERPINB4, SCCA2
Domain Architecture
Description	Serpin B4 (Squamous cell carcinoma antigen 2) (SCCA-2) (Leupin).

SPB13_HUMAN
NC score	0.983957 (rank : 22)	θ value	1.04338e-64 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIV8, Q9HCX1, Q9UBW1, Q9UKG0	Gene names	SERPINB13, PI13
Domain Architecture
Description	Serpin B13 (Hurpin) (HaCaT UV-repressible serpin) (Protease inhibitor 13) (Headpin).

ANT3_MOUSE
NC score	0.976070 (rank : 23)	θ value	8.59492e-43 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P32261	Gene names	Serpinc1, At3
Domain Architecture
Description	Antithrombin-III precursor (ATIII).

ANT3_HUMAN
NC score	0.975082 (rank : 24)	θ value	5.21438e-40 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P01008, P78439, P78447, Q13815, Q7KZ43	Gene names	SERPINC1, AT3
Domain Architecture
Description	Antithrombin-III precursor (ATIII).

SPI2_MOUSE
NC score	0.974019 (rank : 25)	θ value	2.67181e-44 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JK88, Q9D8Z3, Q9D955	Gene names	Serpini2, Spi14
Domain Architecture
Description	Serpin I2 precursor (Serine protease inhibitor 14).

SPI2_HUMAN
NC score	0.973207 (rank : 26)	θ value	5.03882e-43 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	O75830	Gene names	SERPINI2, MEPI, PI14
Domain Architecture
Description	Serpin I2 precursor (Myoepithelium-derived serine protease inhibitor) (Pancpin) (Protease inhibitor 14) (TSA2004).

NEUS_HUMAN
NC score	0.970298 (rank : 27)	θ value	9.83387e-39 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q99574, Q6AHZ4	Gene names	SERPINI1, PI12
Domain Architecture
Description	Neuroserpin precursor (Serpin I1) (Protease inhibitor 12).

NEUS_MOUSE
NC score	0.968251 (rank : 28)	θ value	1.98146e-39 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	O35684, Q543F7, Q922U6	Gene names	Serpini1, Pi12, Spi17
Domain Architecture
Description	Neuroserpin precursor (Serpin I1) (Protease inhibitor 17).

PAI1_MOUSE
NC score	0.966673 (rank : 29)	θ value	2.05049e-36 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	77	Shared Neighborhood Hits	75
SwissProt Accessions	P22777	Gene names	Serpine1, Mr1, Pai1, Planh1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

GDN_MOUSE
NC score	0.964999 (rank : 30)	θ value	5.0505e-35 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	Q07235, Q921T7	Gene names	Serpine2, Pi7, Pn1, Spi4
Domain Architecture
Description	Glia-derived nexin precursor (GDN) (Protease nexin I) (PN-1) (Serine protease-inhibitor 4).

HEP2_MOUSE
NC score	0.964434 (rank : 31)	θ value	9.83387e-39 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P49182	Gene names	Serpind1, Hcf2, Hcii
Domain Architecture
Description	Heparin cofactor 2 precursor (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin 2).

GDN_HUMAN
NC score	0.964380 (rank : 32)	θ value	3.3877e-31 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	P07093	Gene names	SERPINE2, PI7, PN1
Domain Architecture
Description	Glia-derived nexin precursor (GDN) (Protease nexin I) (PN-1) (Protease inhibitor 7).

SERPH_HUMAN
NC score	0.963850 (rank : 33)	θ value	3.16345e-37 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P50454, P29043, Q5XPB4, Q6NSJ6, Q8IY96, Q9NP88	Gene names	SERPINH1, CBP1, CBP2, HSP47, PIG14, SERPINH2
Domain Architecture
Description	Serpin H1 precursor (Collagen-binding protein) (Colligin) (47 kDa heat shock protein) (Rheumatoid arthritis-related antigen RA-A47) (Arsenic- transactivated protein 3) (AsTP3) (Proliferation-inducing gene 14 protein).

SERPH_MOUSE
NC score	0.963725 (rank : 34)	θ value	2.67802e-36 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P19324	Gene names	Serpinh1, Cbp1, Hsp47
Domain Architecture
Description	Serpin H1 precursor (Collagen-binding protein) (Colligin) (47 kDa heat shock protein) (Serine protease inhibitor J6).

HEP2_HUMAN
NC score	0.963560 (rank : 35)	θ value	4.88048e-38 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P05546, Q6IBZ5	Gene names	SERPIND1, HCF2
Domain Architecture
Description	Heparin cofactor 2 precursor (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin 2) (HLS2).

PAI1_HUMAN
NC score	0.962502 (rank : 36)	θ value	3.4976e-36 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P05121	Gene names	SERPINE1, PAI1, PLANH1
Domain Architecture
Description	Plasminogen activator inhibitor 1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI).

SPA12_MOUSE
NC score	0.952256 (rank : 37)	θ value	4.13158e-37 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TMF5, Q9CQ32	Gene names	Serpina12
Domain Architecture	No domain graphic available
Description	Serpin A12 precursor (Visceral adipose-specific serpin) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin).

SPA9_MOUSE
NC score	0.950555 (rank : 38)	θ value	7.52953e-39 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D7D2	Gene names	Serpina9
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor.

ZPI_MOUSE
NC score	0.949856 (rank : 39)	θ value	7.80994e-28 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R121, Q8VCV8	Gene names	Serpina10, Zpi
Domain Architecture	No domain graphic available
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

IPSP_HUMAN
NC score	0.947944 (rank : 40)	θ value	9.52487e-34 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P05154, Q07616, Q9UG30	Gene names	SERPINA5, PCI, PLANH3, PROCI
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Acrosomal serine protease inhibitor).

ZPI_HUMAN
NC score	0.946205 (rank : 41)	θ value	6.84181e-24 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK55, Q6UWX9, Q86U20	Gene names	SERPINA10, ZPI
Domain Architecture
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

SPA12_HUMAN
NC score	0.946089 (rank : 42)	θ value	1.57e-36 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IW75	Gene names	SERPINA12
Domain Architecture	No domain graphic available
Description	Serpin A12 precursor (Visceral adipose-specific serpin) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (OL-64).

AACT_HUMAN
NC score	0.946067 (rank : 43)	θ value	1.85459e-37 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P01011, Q13703, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UNU9	Gene names	SERPINA3, AACT
Domain Architecture
Description	Alpha-1-antichymotrypsin precursor (ACT) [Contains: Alpha-1- antichymotrypsin His-Pro-less].

SPA9_HUMAN
NC score	0.945290 (rank : 44)	θ value	2.05049e-36 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86WD7, Q6UWP9, Q86WD6, Q86YP6, Q86YP7	Gene names	SERPINA9, GCET1, SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor (Germinal center B-cell expressed transcript 1 protein).

SPA3C_MOUSE
NC score	0.944242 (rank : 45)	θ value	7.27602e-42 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	78	Shared Neighborhood Hits	75
SwissProt Accessions	P29621	Gene names	Serpina3c, Klkbp
Domain Architecture
Description	Serine protease inhibitor A3C precursor (Kallikrein-binding protein) (KBP) (Serpin A3C).

THBG_HUMAN
NC score	0.942808 (rank : 46)	θ value	3.05695e-40 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P05543	Gene names	SERPINA7, TBG
Domain Architecture
Description	Thyroxine-binding globulin precursor (T4-binding globulin) (Serpin A7).

CBG_HUMAN
NC score	0.942391 (rank : 47)	θ value	2.05525e-28 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P08185, Q7Z2Q9	Gene names	SERPINA6, CBG
Domain Architecture
Description	Corticosteroid-binding globulin precursor (CBG) (Transcortin) (Serpin A6).

THBG_MOUSE
NC score	0.942196 (rank : 48)	θ value	5.584e-34 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	75
SwissProt Accessions	P61939	Gene names	Serpina7, Tbg
Domain Architecture	No domain graphic available
Description	Thyroxine-binding globulin precursor (T4-binding globulin) (Serpin A7).

A2AP_HUMAN
NC score	0.941274 (rank : 49)	θ value	3.28125e-26 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P08697	Gene names	SERPINF2, AAP, PLI
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

SPA3K_MOUSE
NC score	0.940948 (rank : 50)	θ value	1.05066e-40 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P07759, Q91W80, Q91X80	Gene names	Serpina3k, Mcm2, Spi2
Domain Architecture
Description	Serine protease inhibitor A3K precursor (Contrapsin) (Serpin A3K).

IPSP_MOUSE
NC score	0.940395 (rank : 51)	θ value	1.98606e-31 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P70458	Gene names	Serpina5, Pci
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3).

A1AT_HUMAN
NC score	0.940137 (rank : 52)	θ value	8.61488e-35 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P01009, Q13672, Q5U0M1, Q96BF9, Q96ES1, Q9P1P0	Gene names	SERPINA1, AAT, PI
Domain Architecture
Description	Alpha-1-antitrypsin precursor (Alpha-1 protease inhibitor) (Alpha-1- antiproteinase).

SPA3M_MOUSE
NC score	0.939950 (rank : 53)	θ value	6.81017e-40 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	Q03734, Q62260	Gene names	Serpina3m
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3M precursor (Serpin A3M).

A2AP_MOUSE
NC score	0.939566 (rank : 54)	θ value	2.12685e-25 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q61247	Gene names	Serpinf2, Pli
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

SPA3B_MOUSE
NC score	0.939362 (rank : 55)	θ value	3.61944e-33 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BYY9	Gene names	Serpina3b
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3B precursor (Serpin A3B).

SPA3F_MOUSE
NC score	0.938260 (rank : 56)	θ value	2.86122e-38 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	Q80X76	Gene names	Serpina3f
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3F (Serpin A3F).

SPA3N_MOUSE
NC score	0.937542 (rank : 57)	θ value	1.20211e-36 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).

SPA3G_MOUSE
NC score	0.936371 (rank : 58)	θ value	2.96089e-35 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	Q5I2A0, Q6PG99	Gene names	Serpina3g, Spi2A
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3G (Serine protease inhibitor 2A) (Serpin A3G) (Serpin 2A).

A1AT4_MOUSE
NC score	0.936358 (rank : 59)	θ value	1.24399e-33 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	75
SwissProt Accessions	Q00897	Gene names	Serpina1d, Dom4, Spi1-4
Domain Architecture
Description	Alpha-1-antitrypsin 1-4 precursor (Serine protease inhibitor 1-4) (Alpha-1 protease inhibitor 4).

SPA11_HUMAN
NC score	0.934954 (rank : 60)	θ value	7.30988e-26 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q86U17	Gene names	SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A11 precursor.

A1AT1_MOUSE
NC score	0.934872 (rank : 61)	θ value	3.61944e-33 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	P07758, Q80YB8, Q8JZV6, Q91XB8	Gene names	Serpina1a, Dom1, Spi1-1
Domain Architecture
Description	Alpha-1-antitrypsin 1-1 precursor (Serine protease inhibitor 1-1) (Alpha-1 protease inhibitor 1) (Alpha-1-antiproteinase) (AAT).

PEDF_MOUSE
NC score	0.934180 (rank : 62)	θ value	3.87602e-27 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	P97298, O70629, O88691	Gene names	Serpinf1, Pedf, Sdf3
Domain Architecture
Description	Pigment epithelium-derived factor precursor (PEDF) (Serpin-F1) (Stromal cell-derived factor 3) (SDF-3) (Caspin).

SPA3A_MOUSE
NC score	0.933955 (rank : 63)	θ value	1.52067e-31 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P4P1, Q9D490	Gene names	Serpina3a
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3A precursor (Serpin A3A).

A1AT5_MOUSE
NC score	0.933873 (rank : 64)	θ value	8.91499e-32 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q00898	Gene names	Serpina1e, Dom5, Spi1-5
Domain Architecture
Description	Alpha-1-antitrypsin 1-5 precursor (Serine protease inhibitor 1-5) (Alpha-1 protease inhibitor 5).

KAIN_HUMAN
NC score	0.933395 (rank : 65)	θ value	5.23862e-24 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P29622, Q53XB5, Q86TR9, Q96BZ5	Gene names	SERPINA4, KST, PI4
Domain Architecture
Description	Kallistatin precursor (Serpin A4) (Kallikrein inhibitor) (Protease inhibitor 4).

SPA11_MOUSE
NC score	0.932115 (rank : 66)	θ value	5.97985e-28 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CIE0	Gene names	Serpina11
Domain Architecture	No domain graphic available
Description	Serpin A11 precursor.

A1AT2_MOUSE
NC score	0.931846 (rank : 67)	θ value	1.6247e-33 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	P22599, Q61283, Q80ZH5, Q8VC20	Gene names	Serpina1b, Aat2, Dom2, Spi1-2
Domain Architecture
Description	Alpha-1-antitrypsin 1-2 precursor (Serine protease inhibitor 1-2) (Alpha-1 protease inhibitor 2) (Alpha-1-antiproteinase) (AAT).

A1AT6_MOUSE
NC score	0.930732 (rank : 68)	θ value	1.0531e-32 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P81105, Q91V74, Q91WH5, Q91XC1	Gene names	Spi1-6, Dom6
Domain Architecture	No domain graphic available
Description	Alpha-1-antitrypsin 1-6 precursor (Serine protease inhibitor 1-6) (Alpha-1 protease inhibitor 6).

CBG_MOUSE
NC score	0.930479 (rank : 69)	θ value	1.47289e-26 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q06770	Gene names	Serpina6, Cbg
Domain Architecture
Description	Corticosteroid-binding globulin precursor (CBG) (Transcortin) (Serpin A6).

A1AT3_MOUSE
NC score	0.930205 (rank : 70)	θ value	1.16434e-31 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q00896	Gene names	Serpina1c, Dom3, Spi1-3
Domain Architecture
Description	Alpha-1-antitrypsin 1-3 precursor (Serine protease inhibitor 1-3) (Alpha-1 protease inhibitor 3).

PEDF_HUMAN
NC score	0.930131 (rank : 71)	θ value	1.73987e-27 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	P36955, Q13236, Q96CT1, Q96R01, Q9BWA4	Gene names	SERPINF1, PEDF
Domain Architecture
Description	Pigment epithelium-derived factor precursor (PEDF) (Serpin-F1) (EPC- 1).

A1ATR_HUMAN
NC score	0.921945 (rank : 72)	θ value	1.2077e-20 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	82	Shared Neighborhood Hits	75
SwissProt Accessions	P20848	Gene names	SERPINA2, ARGS, ATR, PIL
Domain Architecture
Description	Alpha-1-antitrypsin-related protein precursor.

IC1_HUMAN
NC score	0.915414 (rank : 73)	θ value	1.42992e-13 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	99	Shared Neighborhood Hits	75
SwissProt Accessions	P05155, Q547W3, Q59EI5, Q96FE0	Gene names	SERPING1, C1IN, C1NH
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

IC1_MOUSE
NC score	0.904048 (rank : 74)	θ value	1.9326e-10 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	164	Shared Neighborhood Hits	76
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

SPA13_HUMAN
NC score	0.837175 (rank : 75)	θ value	1.43324e-05 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXR4	Gene names	SERPINA13
Domain Architecture	No domain graphic available
Description	Serpin A13 precursor.

ANGT_HUMAN
NC score	0.733388 (rank : 76)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P01019, Q16358, Q16359, Q96F91	Gene names	AGT, SERPINA8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

ANGT_MOUSE
NC score	0.685074 (rank : 77)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	P11859	Gene names	Agt, Serpina8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

P210L_HUMAN
NC score	0.012583 (rank : 78)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

IL18_HUMAN
NC score	0.010518 (rank : 79)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q14116, O75599	Gene names	IL18, IGIF, IL1F4
Domain Architecture
Description	Interleukin-18 precursor (IL-18) (Interferon-gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma) (Iboctadekin).

MAP9_HUMAN
NC score	0.006788 (rank : 80)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CDCP1_MOUSE
NC score	0.005999 (rank : 81)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

RBCC1_MOUSE
NC score	0.005328 (rank : 82)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	1048	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

LIPB1_HUMAN
NC score	0.002694 (rank : 83)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	640	Shared Neighborhood Hits	10
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

RBCC1_HUMAN
NC score	0.001906 (rank : 84)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	1023	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SMC4_MOUSE
NC score	0.001002 (rank : 85)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	830	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

GOGA4_HUMAN
NC score	-0.001005 (rank : 86)	θ value	0.0193708 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	2034	Shared Neighborhood Hits	11
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HECD1_HUMAN
NC score	-0.002122 (rank : 87)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	371	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR26_HUMAN
NC score	-0.003318 (rank : 88)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	1614	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MRCKA_HUMAN
NC score	-0.006224 (rank : 89)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	1999	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

LIMK2_HUMAN
NC score	-0.006544 (rank : 90)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	986	Shared Neighborhood Hits	6
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIMK2_MOUSE
NC score	-0.006652 (rank : 91)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	998	Shared Neighborhood Hits	6
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MRCKB_MOUSE
NC score	-0.006893 (rank : 92)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	2180	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_HUMAN
NC score	-0.007475 (rank : 93)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	2239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).