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Network neighborhood for query Sequence : SOSD1_HUMAN

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SOSD1_HUMAN
SwissProt Accessions	Q6X4U4, Q96HJ7, Q9Y3U3	Gene names	SOSTDC1, USAG1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SOSD1_HUMAN
θ value	1.58377e-121 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q6X4U4, Q96HJ7, Q9Y3U3	Gene names	SOSTDC1, USAG1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1).

SOSD1_MOUSE
θ value	5.82922e-116 (rank : 2)	NC score	0.998860 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQN4, Q8CF09	Gene names	Sostdc1, Sostl, Usag1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1) (Sclerostin-like protein).

SOST_HUMAN
θ value	1.6813e-30 (rank : 3)	NC score	0.862638 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQB4	Gene names	SOST
Domain Architecture
Description	Sclerostin precursor.

SOST_MOUSE
θ value	5.40856e-29 (rank : 4)	NC score	0.851027 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P68, Q9D3L7	Gene names	Sost
Domain Architecture
Description	Sclerostin precursor.

CYR61_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.093978 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	0.0961366 (rank : 6)	NC score	0.090631 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

MUC2_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.029115 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	906	Shared Neighborhood Hits	7
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

VWF_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.031761 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

AP2B_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.033918 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.033883 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

WISP1_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.061238 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

PDE11_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.010878 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

WISP3_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.061711 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

WISP1_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.056935 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

Hits sorted by NC score

SOSD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.58377e-121 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q6X4U4, Q96HJ7, Q9Y3U3	Gene names	SOSTDC1, USAG1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1).

SOSD1_MOUSE
NC score	0.998860 (rank : 2)	θ value	5.82922e-116 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQN4, Q8CF09	Gene names	Sostdc1, Sostl, Usag1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1) (Sclerostin-like protein).

SOST_HUMAN
NC score	0.862638 (rank : 3)	θ value	1.6813e-30 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQB4	Gene names	SOST
Domain Architecture
Description	Sclerostin precursor.

SOST_MOUSE
NC score	0.851027 (rank : 4)	θ value	5.40856e-29 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P68, Q9D3L7	Gene names	Sost
Domain Architecture
Description	Sclerostin precursor.

CYR61_HUMAN
NC score	0.093978 (rank : 5)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
NC score	0.090631 (rank : 6)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

WISP3_HUMAN
NC score	0.061711 (rank : 7)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

WISP1_HUMAN
NC score	0.061238 (rank : 8)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
NC score	0.056935 (rank : 9)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

AP2B_HUMAN
NC score	0.033918 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
NC score	0.033883 (rank : 11)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

VWF_MOUSE
NC score	0.031761 (rank : 12)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC2_HUMAN
NC score	0.029115 (rank : 13)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	906	Shared Neighborhood Hits	7
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PDE11_HUMAN
NC score	0.010878 (rank : 14)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).