Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SIA7B_HUMAN

For an explanation of this page, click here

SIA7B_HUMAN
SwissProt Accessions	Q9UJ37, Q12971	Gene names	ST6GALNAC2, SIAT7B, STHM
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (Sialyltransferase 7B) (SThM).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SIA7B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJ37, Q12971	Gene names	ST6GALNAC2, SIAT7B, STHM
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (Sialyltransferase 7B) (SThM).

SIA7B_MOUSE
θ value	9.49765e-159 (rank : 2)	NC score	0.994777 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	P70277, Q3UWG0, Q9DC24	Gene names	St6galnac2, Siat7, Siat7b
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase) (Sialyltransferase 7B).

SIA7A_MOUSE
θ value	1.31681e-67 (rank : 3)	NC score	0.926470 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SIA7A_HUMAN
θ value	6.53529e-67 (rank : 4)	NC score	0.922032 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SIA4B_HUMAN
θ value	5.99374e-20 (rank : 5)	NC score	0.810393 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q16842, O00654	Gene names	ST3GAL2, SIAT4B
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalA.2) (SIAT4-B) (ST3Gal II).

SIA4B_MOUSE
θ value	6.62687e-19 (rank : 6)	NC score	0.808606 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q11204	Gene names	St3gal2, Siat4b, Siat5
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalA.2) (SIAT4-B) (ST3Gal II).

SIA4A_HUMAN
θ value	1.92812e-18 (rank : 7)	NC score	0.818062 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q11201, O60677, Q9UN51	Gene names	ST3GAL1, SIAT4, SIAT4A
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I) (SIATFL).

SIA4A_MOUSE
θ value	3.63628e-17 (rank : 8)	NC score	0.812914 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	P54751, Q11202	Gene names	St3gal1, Siat4, Siat4a
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I).

SIAT6_MOUSE
θ value	1.52774e-15 (rank : 9)	NC score	0.771514 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P97325	Gene names	St3gal3, Siat3, Siat6
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3- sialyltransferase (EC 2.4.99.6) (N-acetyllactosaminide alpha-2,3- sialyltransferase) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (ST3N) (ST3GalIII) (Sialyltransferase 6).

SIAT6_HUMAN
θ value	5.8054e-15 (rank : 10)	NC score	0.766871 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q11203, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58	Gene names	ST3GAL3, SIAT6
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3- sialyltransferase (EC 2.4.99.6) (N-acetyllactosaminide alpha-2,3- sialyltransferase) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (ST3N) (ST3GalIII) (Sialyltransferase 6).

SIA4C_HUMAN
θ value	7.09661e-13 (rank : 11)	NC score	0.759632 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q11206, O60497, Q96QQ9	Gene names	ST3GAL4, SIAT4C, STZ
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4).

SIA10_MOUSE
θ value	1.58096e-12 (rank : 12)	NC score	0.742270 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VIB3, Q3TRN3, Q80UR7, Q9WVG2	Gene names	St3gal6, Siat10
Domain Architecture
Description	Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP- NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (Sialyltransferase 10).

SIA8E_HUMAN
θ value	2.0648e-12 (rank : 13)	NC score	0.687798 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	O15466	Gene names	ST8SIA5, SIAT8E
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

SIA8C_HUMAN
θ value	3.52202e-12 (rank : 14)	NC score	0.730377 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	O43173, Q9NS41	Gene names	ST8SIA3, SIAT8C
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIA4C_MOUSE
θ value	7.84624e-12 (rank : 15)	NC score	0.755470 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q91Y74	Gene names	St3gal4, Siat4c
Domain Architecture	No domain graphic available
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (SIAT4-C).

SIAT9_HUMAN
θ value	1.02475e-11 (rank : 16)	NC score	0.738312 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UNP4, O94902, Q53QU1	Gene names	ST3GAL5, SIAT9
Domain Architecture
Description	Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9) (CMP- NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (Sialyltransferase 9).

SIA8F_HUMAN
θ value	1.74796e-11 (rank : 17)	NC score	0.674277 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P61647	Gene names	ST8SIA6, SIAT8F
Domain Architecture	No domain graphic available
Description	Alpha-2,8-sialyltransferase 8F (EC 2.4.99.-) (ST8Sia VI).

SIAT9_MOUSE
θ value	2.98157e-11 (rank : 18)	NC score	0.746560 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	O88829	Gene names	St3gal5, Siat9
Domain Architecture
Description	Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9) (CMP- NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (Sialyltransferase 9).

SIA8F_MOUSE
θ value	3.89403e-11 (rank : 19)	NC score	0.688626 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K4T1	Gene names	St8sia6, Siat8f
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8F (EC 2.4.99.-) (ST8Sia VI).

SIA8D_HUMAN
θ value	6.64225e-11 (rank : 20)	NC score	0.706031 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q92187, Q92693	Gene names	ST8SIA4, PST, PST1, SIAT8D
Domain Architecture
Description	CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase- 1).

SIA8E_MOUSE
θ value	8.67504e-11 (rank : 21)	NC score	0.681357 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	P70126, P70127, P70128	Gene names	St8sia5, Siat8e, St8siav
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

SIA8C_MOUSE
θ value	1.133e-10 (rank : 22)	NC score	0.721733 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q64689	Gene names	St8sia3, Siat8c
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIA8D_MOUSE
θ value	1.47974e-10 (rank : 23)	NC score	0.703369 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q64692	Gene names	St8sia4, Pst, Siat8d
Domain Architecture
Description	CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase- 1).

SIAT1_MOUSE
θ value	4.30538e-10 (rank : 24)	NC score	0.712781 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q64685	Gene names	St6gal1, Siat1
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase (EC 2.4.99.1) (Beta-galactoside alpha-2,6-sialyltransferase) (Alpha 2,6-ST) (Sialyltransferase 1) (ST6Gal I).

SIA10_HUMAN
θ value	7.34386e-10 (rank : 25)	NC score	0.731233 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y274	Gene names	ST3GAL6, SIAT10
Domain Architecture
Description	Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP- NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (Sialyltransferase 10).

SIA8B_MOUSE
θ value	2.79066e-09 (rank : 26)	NC score	0.699722 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O35696	Gene names	St8sia2, Siat8b, Stx
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (ST8Sia II) (Sialyltransferase X) (STX) (Polysialic acid synthase).

SIAT1_HUMAN
θ value	3.64472e-09 (rank : 27)	NC score	0.705330 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	P15907	Gene names	ST6GAL1, SIAT1
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase (EC 2.4.99.1) (Beta-galactoside alpha-2,6-sialyltransferase) (Alpha 2,6-ST) (Sialyltransferase 1) (ST6Gal I) (B-cell antigen CD75).

SIA8B_HUMAN
θ value	8.11959e-09 (rank : 28)	NC score	0.693418 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q92186, Q4VAZ0, Q92470, Q92746	Gene names	ST8SIA2, SIAT8B, STX
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (ST8Sia II) (Sialyltransferase X) (STX).

SIA8A_HUMAN
θ value	1.99992e-07 (rank : 29)	NC score	0.653557 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q92185, Q93064	Gene names	ST8SIA1, SIAT8, SIAT8A
Domain Architecture
Description	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Alpha-2,8- sialyltransferase 8A) (ST8Sia I).

SIA8A_MOUSE
θ value	9.92553e-07 (rank : 30)	NC score	0.646486 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q64687	Gene names	St8sia1, Siat8, Siat8a
Domain Architecture
Description	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Alpha-2,8- sialyltransferase 8A) (ST8Sia I).

SIA7E_HUMAN
θ value	1.69304e-06 (rank : 31)	NC score	0.604517 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BVH7	Gene names	ST6GALNAC5, SIAT7E
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (GD1 alpha synthase) (Sialyltransferase 7E).

SIA7D_HUMAN
θ value	6.43352e-06 (rank : 32)	NC score	0.599270 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4F1, Q9NWU6, Q9UKU1, Q9ULB9, Q9Y3G3, Q9Y3G4	Gene names	ST6GALNAC4, SIAT3C, SIAT7D
Domain Architecture
Description	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl- galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc- alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (Sialyltransferase 7D) (Sialyltransferase 3C).

SIA7D_MOUSE
θ value	1.09739e-05 (rank : 33)	NC score	0.603401 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R2B6, O88725, Q9JHP0, Q9QUP9, Q9R2B5	Gene names	St6galnac4, Siat7d
Domain Architecture
Description	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl- galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc- alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (Sialyltransferase 7D).

SIA7E_MOUSE
θ value	3.19293e-05 (rank : 34)	NC score	0.579372 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYJ1, Q9R0K6	Gene names	St6galnac5, Siat7e
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (GD1 alpha synthase) (Sialyltransferase 7E).

SIA7C_MOUSE
θ value	0.000121331 (rank : 35)	NC score	0.553999 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WUV2, Q9JHP5	Gene names	St6galnac3, Siat7c
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (Sialyltransferase 7C) (STY).

SIA7C_HUMAN
θ value	0.000270298 (rank : 36)	NC score	0.548887 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDV1, Q6UX29, Q8N259	Gene names	ST6GALNAC3, SIAT7C
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (Sialyltransferase 7C) (STY).

IRK4_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.005449 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

IRK4_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.005452 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

Hits sorted by NC score

SIA7B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJ37, Q12971	Gene names	ST6GALNAC2, SIAT7B, STHM
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (Sialyltransferase 7B) (SThM).

SIA7B_MOUSE
NC score	0.994777 (rank : 2)	θ value	9.49765e-159 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	P70277, Q3UWG0, Q9DC24	Gene names	St6galnac2, Siat7, Siat7b
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase II) (ST6GalNAc II) (Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase) (Sialyltransferase 7B).

SIA7A_MOUSE
NC score	0.926470 (rank : 3)	θ value	1.31681e-67 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SIA7A_HUMAN
NC score	0.922032 (rank : 4)	θ value	6.53529e-67 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	177	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SIA4A_HUMAN
NC score	0.818062 (rank : 5)	θ value	1.92812e-18 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q11201, O60677, Q9UN51	Gene names	ST3GAL1, SIAT4, SIAT4A
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I) (SIATFL).

SIA4A_MOUSE
NC score	0.812914 (rank : 6)	θ value	3.63628e-17 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	P54751, Q11202	Gene names	St3gal1, Siat4, Siat4a
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I).

SIA4B_HUMAN
NC score	0.810393 (rank : 7)	θ value	5.99374e-20 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q16842, O00654	Gene names	ST3GAL2, SIAT4B
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalA.2) (SIAT4-B) (ST3Gal II).

SIA4B_MOUSE
NC score	0.808606 (rank : 8)	θ value	6.62687e-19 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q11204	Gene names	St3gal2, Siat4b, Siat5
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-ST) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3GalA.2) (SIAT4-B) (ST3Gal II).

SIAT6_MOUSE
NC score	0.771514 (rank : 9)	θ value	1.52774e-15 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P97325	Gene names	St3gal3, Siat3, Siat6
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3- sialyltransferase (EC 2.4.99.6) (N-acetyllactosaminide alpha-2,3- sialyltransferase) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (ST3N) (ST3GalIII) (Sialyltransferase 6).

SIAT6_HUMAN
NC score	0.766871 (rank : 10)	θ value	5.8054e-15 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q11203, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58	Gene names	ST3GAL3, SIAT6
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3- sialyltransferase (EC 2.4.99.6) (N-acetyllactosaminide alpha-2,3- sialyltransferase) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (ST3N) (ST3GalIII) (Sialyltransferase 6).

SIA4C_HUMAN
NC score	0.759632 (rank : 11)	θ value	7.09661e-13 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q11206, O60497, Q96QQ9	Gene names	ST3GAL4, SIAT4C, STZ
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4).

SIA4C_MOUSE
NC score	0.755470 (rank : 12)	θ value	7.84624e-12 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q91Y74	Gene names	St3gal4, Siat4c
Domain Architecture	No domain graphic available
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (SIAT4-C).

SIAT9_MOUSE
NC score	0.746560 (rank : 13)	θ value	2.98157e-11 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	O88829	Gene names	St3gal5, Siat9
Domain Architecture
Description	Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9) (CMP- NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (Sialyltransferase 9).

SIA10_MOUSE
NC score	0.742270 (rank : 14)	θ value	1.58096e-12 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VIB3, Q3TRN3, Q80UR7, Q9WVG2	Gene names	St3gal6, Siat10
Domain Architecture
Description	Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP- NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (Sialyltransferase 10).

SIAT9_HUMAN
NC score	0.738312 (rank : 15)	θ value	1.02475e-11 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UNP4, O94902, Q53QU1	Gene names	ST3GAL5, SIAT9
Domain Architecture
Description	Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9) (CMP- NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (Sialyltransferase 9).

SIA10_HUMAN
NC score	0.731233 (rank : 16)	θ value	7.34386e-10 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y274	Gene names	ST3GAL6, SIAT10
Domain Architecture
Description	Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP- NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (Sialyltransferase 10).

SIA8C_HUMAN
NC score	0.730377 (rank : 17)	θ value	3.52202e-12 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	O43173, Q9NS41	Gene names	ST8SIA3, SIAT8C
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIA8C_MOUSE
NC score	0.721733 (rank : 18)	θ value	1.133e-10 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q64689	Gene names	St8sia3, Siat8c
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIAT1_MOUSE
NC score	0.712781 (rank : 19)	θ value	4.30538e-10 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q64685	Gene names	St6gal1, Siat1
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase (EC 2.4.99.1) (Beta-galactoside alpha-2,6-sialyltransferase) (Alpha 2,6-ST) (Sialyltransferase 1) (ST6Gal I).

SIA8D_HUMAN
NC score	0.706031 (rank : 20)	θ value	6.64225e-11 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q92187, Q92693	Gene names	ST8SIA4, PST, PST1, SIAT8D
Domain Architecture
Description	CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase- 1).

SIAT1_HUMAN
NC score	0.705330 (rank : 21)	θ value	3.64472e-09 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	P15907	Gene names	ST6GAL1, SIAT1
Domain Architecture
Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase (EC 2.4.99.1) (Beta-galactoside alpha-2,6-sialyltransferase) (Alpha 2,6-ST) (Sialyltransferase 1) (ST6Gal I) (B-cell antigen CD75).

SIA8D_MOUSE
NC score	0.703369 (rank : 22)	θ value	1.47974e-10 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q64692	Gene names	St8sia4, Pst, Siat8d
Domain Architecture
Description	CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase- 1).

SIA8B_MOUSE
NC score	0.699722 (rank : 23)	θ value	2.79066e-09 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O35696	Gene names	St8sia2, Siat8b, Stx
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (ST8Sia II) (Sialyltransferase X) (STX) (Polysialic acid synthase).

SIA8B_HUMAN
NC score	0.693418 (rank : 24)	θ value	8.11959e-09 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q92186, Q4VAZ0, Q92470, Q92746	Gene names	ST8SIA2, SIAT8B, STX
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (ST8Sia II) (Sialyltransferase X) (STX).

SIA8F_MOUSE
NC score	0.688626 (rank : 25)	θ value	3.89403e-11 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K4T1	Gene names	St8sia6, Siat8f
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8F (EC 2.4.99.-) (ST8Sia VI).

SIA8E_HUMAN
NC score	0.687798 (rank : 26)	θ value	2.0648e-12 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	O15466	Gene names	ST8SIA5, SIAT8E
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

SIA8E_MOUSE
NC score	0.681357 (rank : 27)	θ value	8.67504e-11 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	P70126, P70127, P70128	Gene names	St8sia5, Siat8e, St8siav
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

SIA8F_HUMAN
NC score	0.674277 (rank : 28)	θ value	1.74796e-11 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P61647	Gene names	ST8SIA6, SIAT8F
Domain Architecture	No domain graphic available
Description	Alpha-2,8-sialyltransferase 8F (EC 2.4.99.-) (ST8Sia VI).

SIA8A_HUMAN
NC score	0.653557 (rank : 29)	θ value	1.99992e-07 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q92185, Q93064	Gene names	ST8SIA1, SIAT8, SIAT8A
Domain Architecture
Description	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Alpha-2,8- sialyltransferase 8A) (ST8Sia I).

SIA8A_MOUSE
NC score	0.646486 (rank : 30)	θ value	9.92553e-07 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q64687	Gene names	St8sia1, Siat8, Siat8a
Domain Architecture
Description	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Alpha-2,8- sialyltransferase 8A) (ST8Sia I).

SIA7E_HUMAN
NC score	0.604517 (rank : 31)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BVH7	Gene names	ST6GALNAC5, SIAT7E
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (GD1 alpha synthase) (Sialyltransferase 7E).

SIA7D_MOUSE
NC score	0.603401 (rank : 32)	θ value	1.09739e-05 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R2B6, O88725, Q9JHP0, Q9QUP9, Q9R2B5	Gene names	St6galnac4, Siat7d
Domain Architecture
Description	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl- galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc- alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (Sialyltransferase 7D).

SIA7D_HUMAN
NC score	0.599270 (rank : 33)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4F1, Q9NWU6, Q9UKU1, Q9ULB9, Q9Y3G3, Q9Y3G4	Gene names	ST6GALNAC4, SIAT3C, SIAT7D
Domain Architecture
Description	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl- galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc- alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (Sialyltransferase 7D) (Sialyltransferase 3C).

SIA7E_MOUSE
NC score	0.579372 (rank : 34)	θ value	3.19293e-05 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYJ1, Q9R0K6	Gene names	St6galnac5, Siat7e
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (GD1 alpha synthase) (Sialyltransferase 7E).

SIA7C_MOUSE
NC score	0.553999 (rank : 35)	θ value	0.000121331 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WUV2, Q9JHP5	Gene names	St6galnac3, Siat7c
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (Sialyltransferase 7C) (STY).

SIA7C_HUMAN
NC score	0.548887 (rank : 36)	θ value	0.000270298 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDV1, Q6UX29, Q8N259	Gene names	ST6GALNAC3, SIAT7C
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (Sialyltransferase 7C) (STY).

IRK4_MOUSE
NC score	0.005452 (rank : 37)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

IRK4_HUMAN
NC score	0.005449 (rank : 38)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).