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Network neighborhood for query Sequence : RPO3D_HUMAN

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RPO3D_HUMAN
SwissProt Accessions	P05423, Q6FI28, Q9BPV7, Q9BPZ1, Q9BXB3	Gene names	POLR3D, BN51, BN51T
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4) (RPC53) (Protein BN51).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RPO3D_HUMAN
θ value	3.0341e-181 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P05423, Q6FI28, Q9BPV7, Q9BPZ1, Q9BXB3	Gene names	POLR3D, BN51, BN51T
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4) (RPC53) (Protein BN51).

RPO3D_MOUSE
θ value	1.66873e-171 (rank : 2)	NC score	0.995370 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD1, Q9CZ02	Gene names	Polr3d, Bn51t
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4).

NAF1_HUMAN
θ value	0.0563607 (rank : 3)	NC score	0.057219 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	937	Shared Neighborhood Hits	3
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

STAR8_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.041156 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	216	Shared Neighborhood Hits	3
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

GCF_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.057569 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

NEB2_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.024623 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	883	Shared Neighborhood Hits	4
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.024310 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TERT_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.027543 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

IPO4_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.019981 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

LTBP2_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.008542 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	617	Shared Neighborhood Hits	3
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SUZ12_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.019988 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q15022, Q96BD9	Gene names	SUZ12, CHET9, JJAZ1, KIAA0160
Domain Architecture	No domain graphic available
Description	Polycomb protein SUZ12 (Suppressor of zeste 12 protein homolog) (Joined to JAZF1 protein) (Chromatin precipitated E2F target 9 protein) (ChET 9 protein).

PKCB1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.011151 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	488	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

Hits sorted by NC score

RPO3D_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.0341e-181 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P05423, Q6FI28, Q9BPV7, Q9BPZ1, Q9BXB3	Gene names	POLR3D, BN51, BN51T
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4) (RPC53) (Protein BN51).

RPO3D_MOUSE
NC score	0.995370 (rank : 2)	θ value	1.66873e-171 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD1, Q9CZ02	Gene names	Polr3d, Bn51t
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4).

GCF_HUMAN
NC score	0.057569 (rank : 3)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P16383, O95032	Gene names	TCF9, C2orf3
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9).

NAF1_HUMAN
NC score	0.057219 (rank : 4)	θ value	0.0563607 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	937	Shared Neighborhood Hits	3
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

STAR8_HUMAN
NC score	0.041156 (rank : 5)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	216	Shared Neighborhood Hits	3
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

TERT_HUMAN
NC score	0.027543 (rank : 6)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O14746, O14783, Q2XS35, Q8N6C3	Gene names	TERT, EST2, TCS1, TRT
Domain Architecture	No domain graphic available
Description	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit) (HEST2) (Telomerase-associated protein 2) (TP2).

NEB2_HUMAN
NC score	0.024623 (rank : 7)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	883	Shared Neighborhood Hits	4
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.024310 (rank : 8)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SUZ12_HUMAN
NC score	0.019988 (rank : 9)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q15022, Q96BD9	Gene names	SUZ12, CHET9, JJAZ1, KIAA0160
Domain Architecture	No domain graphic available
Description	Polycomb protein SUZ12 (Suppressor of zeste 12 protein homolog) (Joined to JAZF1 protein) (Chromatin precipitated E2F target 9 protein) (ChET 9 protein).

IPO4_HUMAN
NC score	0.019981 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

PKCB1_HUMAN
NC score	0.011151 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	488	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

LTBP2_MOUSE
NC score	0.008542 (rank : 12)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	617	Shared Neighborhood Hits	3
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).