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Network neighborhood for query Sequence : RPF53_HUMAN

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RPF53_HUMAN
SwissProt Accessions	Q9GZS1, Q5VZT3, Q8NBA9, Q96L20	Gene names	PRAF1, PAF53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RPF53_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZS1, Q5VZT3, Q8NBA9, Q96L20	Gene names	PRAF1, PAF53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

RPF53_MOUSE
θ value	1.97121e-172 (rank : 2)	NC score	0.987246 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K202, Q62034, Q8BQG9	Gene names	Praf1, Paf53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

GRIP2_HUMAN
θ value	1.81305 (rank : 3)	NC score	0.020212 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

HOOK3_MOUSE
θ value	1.81305 (rank : 4)	NC score	0.011184 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	1007	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

RTN4_HUMAN
θ value	3.0926 (rank : 5)	NC score	0.021094 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CRSP2_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.028473 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

PDE4C_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.010534 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

SYTL1_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.012831 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

MYO15_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.007151 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TACC3_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.013446 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	607	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

PTN11_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.008975 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.008976 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

Hits sorted by NC score

RPF53_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZS1, Q5VZT3, Q8NBA9, Q96L20	Gene names	PRAF1, PAF53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

RPF53_MOUSE
NC score	0.987246 (rank : 2)	θ value	1.97121e-172 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K202, Q62034, Q8BQG9	Gene names	Praf1, Paf53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

CRSP2_HUMAN
NC score	0.028473 (rank : 3)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

RTN4_HUMAN
NC score	0.021094 (rank : 4)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

GRIP2_HUMAN
NC score	0.020212 (rank : 5)	θ value	1.81305 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

TACC3_MOUSE
NC score	0.013446 (rank : 6)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	607	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

SYTL1_MOUSE
NC score	0.012831 (rank : 7)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

HOOK3_MOUSE
NC score	0.011184 (rank : 8)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	1007	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

PDE4C_MOUSE
NC score	0.010534 (rank : 9)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

PTN11_MOUSE
NC score	0.008976 (rank : 10)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.008975 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

MYO15_MOUSE
NC score	0.007151 (rank : 12)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).