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Network neighborhood for query Sequence : RHPN2_MOUSE

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RHPN2_MOUSE
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHPN2_HUMAN
θ value	0 (rank : 1)	NC score	0.988081 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RHPN1_HUMAN
θ value	1.33764e-128 (rank : 3)	NC score	0.881688 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	2.97994e-128 (rank : 4)	NC score	0.855143 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PTN23_MOUSE
θ value	1.08979e-29 (rank : 5)	NC score	0.353918 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	726	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN23_HUMAN
θ value	1.57365e-28 (rank : 6)	NC score	0.351084 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PDC6I_HUMAN
θ value	5.60996e-18 (rank : 7)	NC score	0.579057 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	1.63225e-17 (rank : 8)	NC score	0.580689 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

SYNP2_MOUSE
θ value	0.00509761 (rank : 9)	NC score	0.182065 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	252	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYNP2_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.171117 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ARHGB_HUMAN
θ value	0.0148317 (rank : 11)	NC score	0.137151 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	375	Shared Neighborhood Hits	41
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LIN7C_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.162796 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.0148317 (rank : 13)	NC score	0.162796 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SDCB1_HUMAN
θ value	0.0193708 (rank : 14)	NC score	0.137029 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	150	Shared Neighborhood Hits	34
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.135120 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB2_MOUSE
θ value	0.0736092 (rank : 16)	NC score	0.117978 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

LIN7A_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.154749 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.0961366 (rank : 18)	NC score	0.154673 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.152946 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

SM1L2_HUMAN
θ value	0.0961366 (rank : 20)	NC score	0.025426 (rank : 123)
Query Neighborhood Hits	60	Target Neighborhood Hits	1019	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

LIN7B_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.151511 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PDZ11_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.158397 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SYP2L_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.129410 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	400	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ARHGC_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.111197 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	351	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GRIP1_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.121622 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

NXF5_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.034326 (rank : 121)
Query Neighborhood Hits	60	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1B4, Q9H1B0, Q9H1B1, Q9H1B2, Q9H1B3	Gene names	NXF5, TAPL1
Domain Architecture	No domain graphic available
Description	Nuclear RNA export factor 5 (TAP-like protein 1) (TAPL-1).

PDZ11_MOUSE
θ value	0.21417 (rank : 27)	NC score	0.154311 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PP2CG_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.044201 (rank : 119)
Query Neighborhood Hits	60	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PP2CG_MOUSE
θ value	0.279714 (rank : 29)	NC score	0.042832 (rank : 120)
Query Neighborhood Hits	60	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

RGS12_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.113719 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	43
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

GRIP1_MOUSE
θ value	0.365318 (rank : 31)	NC score	0.119258 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

PARD3_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.099257 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	30
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDLI7_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.090338 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	547	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

ARHGC_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.105196 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LNX2_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.081060 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	389	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PARD3_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.093443 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD1_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.122691 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LDB3_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.084648 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	497	Shared Neighborhood Hits	37
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.086990 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	510	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PKN3_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.007655 (rank : 131)
Query Neighborhood Hits	60	Target Neighborhood Hits	1009	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

LNX2_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.078716 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	407	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PDLI7_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.086129 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

WHRN_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.128702 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SDCB2_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.115304 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

PKN3_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.007694 (rank : 130)
Query Neighborhood Hits	60	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ADIP_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.027314 (rank : 122)
Query Neighborhood Hits	60	Target Neighborhood Hits	470	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

LNX1_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.062067 (rank : 95)
Query Neighborhood Hits	60	Target Neighborhood Hits	379	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

GPSM2_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.022575 (rank : 125)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

WHRN_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.115937 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ADIP_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.024999 (rank : 124)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

ASPP1_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.011439 (rank : 129)
Query Neighborhood Hits	60	Target Neighborhood Hits	956	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GPSM2_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.020522 (rank : 126)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

K1333_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.014160 (rank : 127)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PDLI5_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.077542 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	322	Shared Neighborhood Hits	35
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.076119 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

ASPP1_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.011605 (rank : 128)
Query Neighborhood Hits	60	Target Neighborhood Hits	1244	Shared Neighborhood Hits	7
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MPDZ_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.080825 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NHRF2_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.123280 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.123683 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD2_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.087137 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	772	Shared Neighborhood Hits	41
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DLG1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.059258 (rank : 101)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.058734 (rank : 103)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	37
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.057063 (rank : 106)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.057551 (rank : 105)
Query Neighborhood Hits	60	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.056866 (rank : 107)
Query Neighborhood Hits	60	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.057575 (rank : 104)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.059763 (rank : 100)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.060021 (rank : 99)
Query Neighborhood Hits	60	Target Neighborhood Hits	282	Shared Neighborhood Hits	42
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GOPC_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.091991 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	377	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.093483 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GRASP_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.066773 (rank : 90)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.065599 (rank : 91)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRIP2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.098025 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

IL16_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.055166 (rank : 110)
Query Neighborhood Hits	60	Target Neighborhood Hits	207	Shared Neighborhood Hits	32
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.050148 (rank : 118)
Query Neighborhood Hits	60	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

INADL_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.083332 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.079370 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

K1849_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.054508 (rank : 111)
Query Neighborhood Hits	60	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LAP4_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.051920 (rank : 114)
Query Neighborhood Hits	60	Target Neighborhood Hits	608	Shared Neighborhood Hits	41
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.050731 (rank : 116)
Query Neighborhood Hits	60	Target Neighborhood Hits	590	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LNX1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.056548 (rank : 108)
Query Neighborhood Hits	60	Target Neighborhood Hits	377	Shared Neighborhood Hits	33
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.074932 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.075096 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.076464 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	373	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.082705 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	370	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MPDZ_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.080695 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	298	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NHERF_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.111034 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.111222 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PAR3L_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.084238 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDLI1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.077056 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.080986 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.084597 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.091534 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI3_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.075385 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.075853 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	31
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.068131 (rank : 88)
Query Neighborhood Hits	60	Target Neighborhood Hits	245	Shared Neighborhood Hits	33
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.067609 (rank : 89)
Query Neighborhood Hits	60	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDZD1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.106738 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.093189 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.091258 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD7_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.091101 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PSCBP_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.050282 (rank : 117)
Query Neighborhood Hits	60	Target Neighborhood Hits	123	Shared Neighborhood Hits	33
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.053711 (rank : 113)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PTN13_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.072778 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.074169 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	426	Shared Neighborhood Hits	42
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN3_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.064688 (rank : 92)
Query Neighborhood Hits	60	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.062089 (rank : 94)
Query Neighborhood Hits	60	Target Neighborhood Hits	303	Shared Neighborhood Hits	38
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RGS3_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.063741 (rank : 93)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.060312 (rank : 97)
Query Neighborhood Hits	60	Target Neighborhood Hits	1621	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RPGF2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059177 (rank : 102)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPGF6_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.073646 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SHAN2_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.060254 (rank : 98)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.053971 (rank : 112)
Query Neighborhood Hits	60	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNTA1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.070632 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.068932 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	170	Shared Neighborhood Hits	37
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.071080 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.070857 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTB2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.084053 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.084653 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.090937 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.091726 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.077648 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.061174 (rank : 96)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	41
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.104976 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SYP2L_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.106072 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TX1B3_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.068824 (rank : 86)
Query Neighborhood Hits	60	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.068814 (rank : 87)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

USH1C_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.101534 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	327	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.099535 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	557	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZO2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.051259 (rank : 115)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.055655 (rank : 109)
Query Neighborhood Hits	60	Target Neighborhood Hits	224	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

Hits sorted by NC score

RHPN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RHPN2_HUMAN
NC score	0.988081 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN1_HUMAN
NC score	0.881688 (rank : 3)	θ value	1.33764e-128 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
NC score	0.855143 (rank : 4)	θ value	2.97994e-128 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PDC6I_MOUSE
NC score	0.580689 (rank : 5)	θ value	1.63225e-17 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDC6I_HUMAN
NC score	0.579057 (rank : 6)	θ value	5.60996e-18 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PTN23_MOUSE
NC score	0.353918 (rank : 7)	θ value	1.08979e-29 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	726	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN23_HUMAN
NC score	0.351084 (rank : 8)	θ value	1.57365e-28 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SYNP2_MOUSE
NC score	0.182065 (rank : 9)	θ value	0.00509761 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	252	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYNP2_HUMAN
NC score	0.171117 (rank : 10)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

LIN7C_HUMAN
NC score	0.162796 (rank : 11)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.162796 (rank : 12)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PDZ11_HUMAN
NC score	0.158397 (rank : 13)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7A_HUMAN
NC score	0.154749 (rank : 14)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.154673 (rank : 15)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

PDZ11_MOUSE
NC score	0.154311 (rank : 16)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	154	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LIN7B_HUMAN
NC score	0.152946 (rank : 17)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.151511 (rank : 18)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

ARHGB_HUMAN
NC score	0.137151 (rank : 19)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	375	Shared Neighborhood Hits	41
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SDCB1_HUMAN
NC score	0.137029 (rank : 20)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	150	Shared Neighborhood Hits	34
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
NC score	0.135120 (rank : 21)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SYP2L_HUMAN
NC score	0.129410 (rank : 22)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	400	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

WHRN_MOUSE
NC score	0.128702 (rank : 23)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

NHRF2_MOUSE
NC score	0.123683 (rank : 24)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NHRF2_HUMAN
NC score	0.123280 (rank : 25)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZD1_HUMAN
NC score	0.122691 (rank : 26)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

GRIP1_HUMAN
NC score	0.121622 (rank : 27)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.119258 (rank : 28)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

SDCB2_MOUSE
NC score	0.117978 (rank : 29)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

WHRN_HUMAN
NC score	0.115937 (rank : 30)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

SDCB2_HUMAN
NC score	0.115304 (rank : 31)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

RGS12_HUMAN
NC score	0.113719 (rank : 32)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	43
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

NHERF_MOUSE
NC score	0.111222 (rank : 33)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	60	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ARHGC_HUMAN
NC score	0.111197 (rank : 34)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	351	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

NHERF_HUMAN
NC score	0.111034 (rank : 35)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	60	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_MOUSE
NC score	0.106738 (rank : 36)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SYP2L_MOUSE
NC score	0.106072 (rank : 37)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ARHGC_MOUSE
NC score	0.105196 (rank : 38)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SYJ2B_HUMAN
NC score	0.104976 (rank : 39)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	60	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

USH1C_HUMAN
NC score	0.101534 (rank : 40)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	60	Target Neighborhood Hits	327	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.099535 (rank : 41)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	60	Target Neighborhood Hits	557	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PARD3_MOUSE
NC score	0.099257 (rank : 42)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	30
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

GRIP2_HUMAN
NC score	0.098025 (rank : 43)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	256	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

GOPC_MOUSE
NC score	0.093483 (rank : 44)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PARD3_HUMAN
NC score	0.093443 (rank : 45)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD3_HUMAN
NC score	0.093189 (rank : 46)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

GOPC_HUMAN
NC score	0.091991 (rank : 47)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	377	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTG1_MOUSE
NC score	0.091726 (rank : 48)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	60	Target Neighborhood Hits	179	Shared Neighborhood Hits	40
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDLI2_MOUSE
NC score	0.091534 (rank : 49)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	60	Target Neighborhood Hits	220	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDZD3_MOUSE
NC score	0.091258 (rank : 50)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	60	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD7_HUMAN
NC score	0.091101 (rank : 51)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SNTG1_HUMAN
NC score	0.090937 (rank : 52)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDLI7_HUMAN
NC score	0.090338 (rank : 53)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	547	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD2_HUMAN
NC score	0.087137 (rank : 54)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	772	Shared Neighborhood Hits	41
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LDB3_MOUSE
NC score	0.086990 (rank : 55)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	510	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI7_MOUSE
NC score	0.086129 (rank : 56)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SNTB2_MOUSE
NC score	0.084653 (rank : 57)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	60	Target Neighborhood Hits	181	Shared Neighborhood Hits	41
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LDB3_HUMAN
NC score	0.084648 (rank : 58)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	497	Shared Neighborhood Hits	37
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDLI2_HUMAN
NC score	0.084597 (rank : 59)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	60	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PAR3L_HUMAN
NC score	0.084238 (rank : 60)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	60	Target Neighborhood Hits	297	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

SNTB2_HUMAN
NC score	0.084053 (rank : 61)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	60	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

INADL_HUMAN
NC score	0.083332 (rank : 62)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MAGI2_MOUSE
NC score	0.082705 (rank : 63)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	370	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LNX2_HUMAN
NC score	0.081060 (rank : 64)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	389	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PDLI1_MOUSE
NC score	0.080986 (rank : 65)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	60	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

MPDZ_HUMAN
NC score	0.080825 (rank : 66)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
NC score	0.080695 (rank : 67)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	60	Target Neighborhood Hits	298	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_MOUSE
NC score	0.079370 (rank : 68)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LNX2_MOUSE
NC score	0.078716 (rank : 69)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	407	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

SNTG2_HUMAN
NC score	0.077648 (rank : 70)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	60	Target Neighborhood Hits	191	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDLI5_HUMAN
NC score	0.077542 (rank : 71)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	322	Shared Neighborhood Hits	35
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI1_HUMAN
NC score	0.077056 (rank : 72)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

MAGI2_HUMAN
NC score	0.076464 (rank : 73)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	373	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PDLI5_MOUSE
NC score	0.076119 (rank : 74)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI3_MOUSE
NC score	0.075853 (rank : 75)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	31
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_HUMAN
NC score	0.075385 (rank : 76)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	60	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

MAGI1_MOUSE
NC score	0.075096 (rank : 77)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.074932 (rank : 78)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PTN13_MOUSE
NC score	0.074169 (rank : 79)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	60	Target Neighborhood Hits	426	Shared Neighborhood Hits	42
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RPGF6_HUMAN
NC score	0.073646 (rank : 80)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	60	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PTN13_HUMAN
NC score	0.072778 (rank : 81)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	60	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SNTB1_HUMAN
NC score	0.071080 (rank : 82)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	60	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.070857 (rank : 83)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	60	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTA1_HUMAN
NC score	0.070632 (rank : 84)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	60	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
NC score	0.068932 (rank : 85)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	60	Target Neighborhood Hits	170	Shared Neighborhood Hits	37
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

TX1B3_HUMAN
NC score	0.068824 (rank : 86)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	60	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.068814 (rank : 87)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDLI4_HUMAN
NC score	0.068131 (rank : 88)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	60	Target Neighborhood Hits	245	Shared Neighborhood Hits	33
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
NC score	0.067609 (rank : 89)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	60	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GRASP_HUMAN
NC score	0.066773 (rank : 90)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.065599 (rank : 91)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PTN3_HUMAN
NC score	0.064688 (rank : 92)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	60	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RGS3_HUMAN
NC score	0.063741 (rank : 93)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PTN4_HUMAN
NC score	0.062089 (rank : 94)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	60	Target Neighborhood Hits	303	Shared Neighborhood Hits	38
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

LNX1_HUMAN
NC score	0.062067 (rank : 95)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	379	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

SNTG2_MOUSE
NC score	0.061174 (rank : 96)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	41
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

RGS3_MOUSE
NC score	0.060312 (rank : 97)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	60	Target Neighborhood Hits	1621	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SHAN2_HUMAN
NC score	0.060254 (rank : 98)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

DLG4_MOUSE
NC score	0.060021 (rank : 99)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	282	Shared Neighborhood Hits	42
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.059763 (rank : 100)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	42
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_HUMAN
NC score	0.059258 (rank : 101)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

RPGF2_HUMAN
NC score	0.059177 (rank : 102)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

DLG1_MOUSE
NC score	0.058734 (rank : 103)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	37
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_MOUSE
NC score	0.057575 (rank : 104)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG2_MOUSE
NC score	0.057551 (rank : 105)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
NC score	0.057063 (rank : 106)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
NC score	0.056866 (rank : 107)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

LNX1_MOUSE
NC score	0.056548 (rank : 108)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	377	Shared Neighborhood Hits	33
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

ZO3_MOUSE
NC score	0.055655 (rank : 109)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	60	Target Neighborhood Hits	224	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

IL16_HUMAN
NC score	0.055166 (rank : 110)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	207	Shared Neighborhood Hits	32
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

K1849_MOUSE
NC score	0.054508 (rank : 111)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	335	Shared Neighborhood Hits	31
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SHAN2_MOUSE
NC score	0.053971 (rank : 112)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	60	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PSCBP_MOUSE
NC score	0.053711 (rank : 113)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

LAP4_HUMAN
NC score	0.051920 (rank : 114)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	608	Shared Neighborhood Hits	41
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

ZO2_HUMAN
NC score	0.051259 (rank : 115)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LAP4_MOUSE
NC score	0.050731 (rank : 116)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	590	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PSCBP_HUMAN
NC score	0.050282 (rank : 117)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	60	Target Neighborhood Hits	123	Shared Neighborhood Hits	33
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

IL16_MOUSE
NC score	0.050148 (rank : 118)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PP2CG_HUMAN
NC score	0.044201 (rank : 119)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PP2CG_MOUSE
NC score	0.042832 (rank : 120)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

NXF5_HUMAN
NC score	0.034326 (rank : 121)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1B4, Q9H1B0, Q9H1B1, Q9H1B2, Q9H1B3	Gene names	NXF5, TAPL1
Domain Architecture	No domain graphic available
Description	Nuclear RNA export factor 5 (TAP-like protein 1) (TAPL-1).

ADIP_HUMAN
NC score	0.027314 (rank : 122)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	470	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

SM1L2_HUMAN
NC score	0.025426 (rank : 123)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	1019	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

ADIP_MOUSE
NC score	0.024999 (rank : 124)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

GPSM2_HUMAN
NC score	0.022575 (rank : 125)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

GPSM2_MOUSE
NC score	0.020522 (rank : 126)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

K1333_HUMAN
NC score	0.014160 (rank : 127)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

ASPP1_MOUSE
NC score	0.011605 (rank : 128)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	1244	Shared Neighborhood Hits	7
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
NC score	0.011439 (rank : 129)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	956	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PKN3_HUMAN
NC score	0.007694 (rank : 130)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PKN3_MOUSE
NC score	0.007655 (rank : 131)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	1009	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).