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Network neighborhood for query Sequence : PUS3_HUMAN

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PUS3_HUMAN
SwissProt Accessions	Q9BZE2, Q96D17, Q96J23, Q96NB4	Gene names	PUS3
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase 3 (EC 5.4.99.-) (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUS3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZE2, Q96D17, Q96J23, Q96NB4	Gene names	PUS3
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase 3 (EC 5.4.99.-) (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3).

PUS3_MOUSE
θ value	0 (rank : 2)	NC score	0.991654 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI38, Q8BVA6, Q8K0Y3	Gene names	Pus3
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase 3 (EC 5.4.99.-) (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3).

TRUA_HUMAN
θ value	2.88119e-14 (rank : 3)	NC score	0.566505 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y606, Q8WYT2, Q9BU44	Gene names	PUS1
Domain Architecture
Description	tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I).

TRUA_MOUSE
θ value	8.38298e-14 (rank : 4)	NC score	0.555284 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WU56, Q8C250, Q8VDQ3	Gene names	Pus1
Domain Architecture
Description	tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I).

PUSL1_HUMAN
θ value	9.59137e-10 (rank : 5)	NC score	0.543243 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N0Z8	Gene names	PUSL1
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase-like 1 (EC 5.4.99.-) (tRNA-uridine isomerase-like 1) (tRNA pseudouridylate synthase-like 1).

TMF1_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.017307 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	987	Shared Neighborhood Hits	5
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

VAPB_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.039641 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

ETV6_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.024807 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.024833 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

INGR1_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.031107 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

LETM1_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.029529 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

TTLL4_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.019115 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

GCC1_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.014735 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	887	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

VAPB_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.034951 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

CK5P2_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.010048 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1151	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

EP300_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.010691 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GCC1_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.014907 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	777	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

LETM1_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.030090 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

NNP1_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.020991 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

PDK1L_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.003803 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.003773 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

Hits sorted by NC score

PUS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZE2, Q96D17, Q96J23, Q96NB4	Gene names	PUS3
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase 3 (EC 5.4.99.-) (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3).

PUS3_MOUSE
NC score	0.991654 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI38, Q8BVA6, Q8K0Y3	Gene names	Pus3
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase 3 (EC 5.4.99.-) (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3).

TRUA_HUMAN
NC score	0.566505 (rank : 3)	θ value	2.88119e-14 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y606, Q8WYT2, Q9BU44	Gene names	PUS1
Domain Architecture
Description	tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I).

TRUA_MOUSE
NC score	0.555284 (rank : 4)	θ value	8.38298e-14 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WU56, Q8C250, Q8VDQ3	Gene names	Pus1
Domain Architecture
Description	tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I).

PUSL1_HUMAN
NC score	0.543243 (rank : 5)	θ value	9.59137e-10 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N0Z8	Gene names	PUSL1
Domain Architecture	No domain graphic available
Description	tRNA pseudouridine synthase-like 1 (EC 5.4.99.-) (tRNA-uridine isomerase-like 1) (tRNA pseudouridylate synthase-like 1).

VAPB_MOUSE
NC score	0.039641 (rank : 6)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

VAPB_HUMAN
NC score	0.034951 (rank : 7)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

INGR1_MOUSE
NC score	0.031107 (rank : 8)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

LETM1_MOUSE
NC score	0.030090 (rank : 9)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LETM1_HUMAN
NC score	0.029529 (rank : 10)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

ETV6_MOUSE
NC score	0.024833 (rank : 11)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_HUMAN
NC score	0.024807 (rank : 12)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

NNP1_MOUSE
NC score	0.020991 (rank : 13)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

TTLL4_MOUSE
NC score	0.019115 (rank : 14)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

TMF1_HUMAN
NC score	0.017307 (rank : 15)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	987	Shared Neighborhood Hits	5
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

GCC1_MOUSE
NC score	0.014907 (rank : 16)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	777	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_HUMAN
NC score	0.014735 (rank : 17)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	887	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

EP300_HUMAN
NC score	0.010691 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CK5P2_MOUSE
NC score	0.010048 (rank : 19)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1151	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

PDK1L_HUMAN
NC score	0.003803 (rank : 20)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_MOUSE
NC score	0.003773 (rank : 21)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	821	Shared Neighborhood Hits	4
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).