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Network neighborhood for query Sequence : PTTG1_HUMAN

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PTTG1_HUMAN
SwissProt Accessions	O95997	Gene names	PTTG1, EAP1, PTTG, TUTR1
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1) (Tumor-transforming protein 1) (Esp1-associated protein) (hPTTG).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTTG1_HUMAN
θ value	1.03134e-104 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O95997	Gene names	PTTG1, EAP1, PTTG, TUTR1
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1) (Tumor-transforming protein 1) (Esp1-associated protein) (hPTTG).

PTTG1_MOUSE
θ value	9.0981e-77 (rank : 2)	NC score	0.979175 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQJ7, O88887, Q9Z2E6	Gene names	Pttg1, Pttg
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1).

TCF20_HUMAN
θ value	0.47712 (rank : 3)	NC score	0.081668 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

HRX_HUMAN
θ value	0.813845 (rank : 4)	NC score	0.041712 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	825	Shared Neighborhood Hits	6
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TCF20_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.075949 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ANC5_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.063643 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ANC5_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.063502 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

CS021_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.033341 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

DEK_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.027561 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TCOF_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.027684 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TAF3_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.018501 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TXND2_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.016923 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	793	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

PTTG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.03134e-104 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O95997	Gene names	PTTG1, EAP1, PTTG, TUTR1
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1) (Tumor-transforming protein 1) (Esp1-associated protein) (hPTTG).

PTTG1_MOUSE
NC score	0.979175 (rank : 2)	θ value	9.0981e-77 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQJ7, O88887, Q9Z2E6	Gene names	Pttg1, Pttg
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1).

TCF20_HUMAN
NC score	0.081668 (rank : 3)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
NC score	0.075949 (rank : 4)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ANC5_HUMAN
NC score	0.063643 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ANC5_MOUSE
NC score	0.063502 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

HRX_HUMAN
NC score	0.041712 (rank : 7)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	825	Shared Neighborhood Hits	6
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CS021_HUMAN
NC score	0.033341 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

TCOF_HUMAN
NC score	0.027684 (rank : 9)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

DEK_MOUSE
NC score	0.027561 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TAF3_MOUSE
NC score	0.018501 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TXND2_HUMAN
NC score	0.016923 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	793	Shared Neighborhood Hits	7
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).