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Network neighborhood for query Sequence : PRAM3_HUMAN

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PRAM3_HUMAN
SwissProt Accessions	Q5TYW8	Gene names	PRAMEF3
Domain Architecture	No domain graphic available
Description	PRAME family member 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRAM3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TYW8	Gene names	PRAMEF3
Domain Architecture	No domain graphic available
Description	PRAME family member 3.

PRAM1_HUMAN
θ value	3.6091e-158 (rank : 2)	NC score	0.993082 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O95521, Q9UQP2	Gene names	PRAMEF1
Domain Architecture	No domain graphic available
Description	PRAME family member 1.

PRAM2_HUMAN
θ value	1.20145e-153 (rank : 3)	NC score	0.992698 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	O60811	Gene names	PRAMEF2
Domain Architecture	No domain graphic available
Description	PRAME family member 2.

PRA12_HUMAN
θ value	1.99421e-132 (rank : 4)	NC score	0.987126 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

PRAM8_HUMAN
θ value	9.92011e-124 (rank : 5)	NC score	0.985907 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

PRAM7_HUMAN
θ value	6.43005e-123 (rank : 6)	NC score	0.985565 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM9_HUMAN
θ value	1.53401e-116 (rank : 7)	NC score	0.982371 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWM5	Gene names	PRAMEF9
Domain Architecture	No domain graphic available
Description	PRAME family member 9.

PRAM5_HUMAN
θ value	4.4633e-116 (rank : 8)	NC score	0.982131 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TYX0	Gene names	PRAMEF5
Domain Architecture	No domain graphic available
Description	PRAME family member 5.

PRAM6_HUMAN
θ value	5.82922e-116 (rank : 9)	NC score	0.982167 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VXH4	Gene names	PRAMEF6
Domain Architecture	No domain graphic available
Description	PRAME family member 6.

PRAM4_HUMAN
θ value	1.8752e-114 (rank : 10)	NC score	0.982259 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	O60810, Q5LJB5	Gene names	PRAMEF4
Domain Architecture	No domain graphic available
Description	PRAME family member 4.

MAPE_HUMAN
θ value	6.06035e-97 (rank : 11)	NC score	0.982246 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

LRC14_HUMAN
θ value	1.02001e-27 (rank : 12)	NC score	0.887696 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

LRC40_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.020588 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	311	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC40_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.020674 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

NALP5_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.097129 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	560	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NAL12_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.023252 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP2_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.024354 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

MAOX_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.008264 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P06801	Gene names	Me1, Mod-1, Mod1
Domain Architecture
Description	NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) (Malic enzyme 1).

AT2B3_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.002925 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q16720, Q12995, Q16858	Gene names	ATP2B3
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 3 (EC 3.6.3.8) (PMCA3) (Plasma membrane calcium pump isoform 3) (Plasma membrane calcium ATPase isoform 3).

INT1_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.009069 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

LRC3B_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.005312 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	215	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.005311 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	215	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

PZRN3_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.001897 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	461	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LRC31_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.073968 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	139	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NALP1_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.060668 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	138	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.071466 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

Hits sorted by NC score

PRAM3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TYW8	Gene names	PRAMEF3
Domain Architecture	No domain graphic available
Description	PRAME family member 3.

PRAM1_HUMAN
NC score	0.993082 (rank : 2)	θ value	3.6091e-158 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O95521, Q9UQP2	Gene names	PRAMEF1
Domain Architecture	No domain graphic available
Description	PRAME family member 1.

PRAM2_HUMAN
NC score	0.992698 (rank : 3)	θ value	1.20145e-153 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	O60811	Gene names	PRAMEF2
Domain Architecture	No domain graphic available
Description	PRAME family member 2.

PRA12_HUMAN
NC score	0.987126 (rank : 4)	θ value	1.99421e-132 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

PRAM8_HUMAN
NC score	0.985907 (rank : 5)	θ value	9.92011e-124 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

PRAM7_HUMAN
NC score	0.985565 (rank : 6)	θ value	6.43005e-123 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM9_HUMAN
NC score	0.982371 (rank : 7)	θ value	1.53401e-116 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWM5	Gene names	PRAMEF9
Domain Architecture	No domain graphic available
Description	PRAME family member 9.

PRAM4_HUMAN
NC score	0.982259 (rank : 8)	θ value	1.8752e-114 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	O60810, Q5LJB5	Gene names	PRAMEF4
Domain Architecture	No domain graphic available
Description	PRAME family member 4.

MAPE_HUMAN
NC score	0.982246 (rank : 9)	θ value	6.06035e-97 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

PRAM6_HUMAN
NC score	0.982167 (rank : 10)	θ value	5.82922e-116 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VXH4	Gene names	PRAMEF6
Domain Architecture	No domain graphic available
Description	PRAME family member 6.

PRAM5_HUMAN
NC score	0.982131 (rank : 11)	θ value	4.4633e-116 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TYX0	Gene names	PRAMEF5
Domain Architecture	No domain graphic available
Description	PRAME family member 5.

LRC14_HUMAN
NC score	0.887696 (rank : 12)	θ value	1.02001e-27 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

NALP5_MOUSE
NC score	0.097129 (rank : 13)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	560	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

LRC31_HUMAN
NC score	0.073968 (rank : 14)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	139	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NALP5_HUMAN
NC score	0.071466 (rank : 15)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP1_HUMAN
NC score	0.060668 (rank : 16)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	138	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP2_HUMAN
NC score	0.024354 (rank : 17)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL12_HUMAN
NC score	0.023252 (rank : 18)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

LRC40_HUMAN
NC score	0.020674 (rank : 19)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC40_MOUSE
NC score	0.020588 (rank : 20)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	311	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

INT1_HUMAN
NC score	0.009069 (rank : 21)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

MAOX_MOUSE
NC score	0.008264 (rank : 22)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P06801	Gene names	Me1, Mod-1, Mod1
Domain Architecture
Description	NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) (Malic enzyme 1).

LRC3B_HUMAN
NC score	0.005312 (rank : 23)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	215	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
NC score	0.005311 (rank : 24)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	215	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

AT2B3_HUMAN
NC score	0.002925 (rank : 25)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q16720, Q12995, Q16858	Gene names	ATP2B3
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 3 (EC 3.6.3.8) (PMCA3) (Plasma membrane calcium pump isoform 3) (Plasma membrane calcium ATPase isoform 3).

PZRN3_HUMAN
NC score	0.001897 (rank : 26)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	461	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).