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Network neighborhood for query Sequence : PPAC2_MOUSE

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PPAC2_MOUSE
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PPAC2_MOUSE
θ value	5.43074e-130 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC2_HUMAN
θ value	1.29861e-115 (rank : 2)	NC score	0.998073 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY26, Q5JVJ6, Q8NCK9	Gene names	PPAPDC2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC3_MOUSE
θ value	2.7521e-57 (rank : 3)	NC score	0.952751 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PPAC3_HUMAN
θ value	8.85319e-56 (rank : 4)	NC score	0.955266 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBV4, Q5T6P0, Q96SS7, Q9BRC3	Gene names	PPAPDC3, C9orf67
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

SGPP1_MOUSE
θ value	0.00390308 (rank : 5)	NC score	0.202636 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI99	Gene names	Sgpp1, Spp1, Spph1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (SPP) (mSPP1).

SGPP1_HUMAN
θ value	0.00665767 (rank : 6)	NC score	0.196495 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BX95, Q9H189	Gene names	SGPP1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (Spp1) (hSPPase1).

CAC1B_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.024065 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

LPP3_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.095610 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	O14495, Q96GW0, Q99782	Gene names	PPAP2B, LPP3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP).

CAC1B_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.023740 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

LPP3_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.073883 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JY8, Q3TVM4, Q3TXR7, Q8BTB7	Gene names	Ppap2b, Lpp3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta).

TYPH_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.028702 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N42	Gene names	Ecgf1
Domain Architecture
Description	Thymidine phosphorylase (EC 2.4.2.4) (TdRPase) (TP).

SGPP2_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.070273 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWX5, Q8N8Q6	Gene names	SGPP2
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 2 (EC 3.1.3.-) (Sphingosine-1- phosphatase 2) (SPPase2) (Spp2) (hSPP2).

SGPP2_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.066809 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q810K3	Gene names	Sgpp2
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 2 (EC 3.1.3.-) (Sphingosine-1- phosphatase 2) (SPPase2) (Spp2).

Hits sorted by NC score

PPAC2_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.43074e-130 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4F2	Gene names	Ppapdc2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC2_HUMAN
NC score	0.998073 (rank : 2)	θ value	1.29861e-115 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IY26, Q5JVJ6, Q8NCK9	Gene names	PPAPDC2
Domain Architecture	No domain graphic available
Description	Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2).

PPAC3_HUMAN
NC score	0.955266 (rank : 3)	θ value	8.85319e-56 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NBV4, Q5T6P0, Q96SS7, Q9BRC3	Gene names	PPAPDC3, C9orf67
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

PPAC3_MOUSE
NC score	0.952751 (rank : 4)	θ value	2.7521e-57 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB2	Gene names	Ppapdc3
Domain Architecture	No domain graphic available
Description	Probable lipid phosphate phosphatase PPAPDC3 (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 3).

SGPP1_MOUSE
NC score	0.202636 (rank : 5)	θ value	0.00390308 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI99	Gene names	Sgpp1, Spp1, Spph1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (SPP) (mSPP1).

SGPP1_HUMAN
NC score	0.196495 (rank : 6)	θ value	0.00665767 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BX95, Q9H189	Gene names	SGPP1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (Spp1) (hSPPase1).

LPP3_HUMAN
NC score	0.095610 (rank : 7)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	O14495, Q96GW0, Q99782	Gene names	PPAP2B, LPP3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP).

LPP3_MOUSE
NC score	0.073883 (rank : 8)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JY8, Q3TVM4, Q3TXR7, Q8BTB7	Gene names	Ppap2b, Lpp3
Domain Architecture
Description	Lipid phosphate phosphohydrolase 3 (EC 3.1.3.4) (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP- 2b) (PAP2-beta).

SGPP2_HUMAN
NC score	0.070273 (rank : 9)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWX5, Q8N8Q6	Gene names	SGPP2
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 2 (EC 3.1.3.-) (Sphingosine-1- phosphatase 2) (SPPase2) (Spp2) (hSPP2).

SGPP2_MOUSE
NC score	0.066809 (rank : 10)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q810K3	Gene names	Sgpp2
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 2 (EC 3.1.3.-) (Sphingosine-1- phosphatase 2) (SPPase2) (Spp2).

TYPH_MOUSE
NC score	0.028702 (rank : 11)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N42	Gene names	Ecgf1
Domain Architecture
Description	Thymidine phosphorylase (EC 2.4.2.4) (TdRPase) (TP).

CAC1B_MOUSE
NC score	0.024065 (rank : 12)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_HUMAN
NC score	0.023740 (rank : 13)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).